| Organism name | Helianthus tuberosus |
|---|---|
| Genus | Helianthus |
| Family | Asteraceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Helianthus tuberosus |
|---|---|
| Linked NCBI taxonomy ID | 4233 |
| Linked level | species |
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00000235
|
Heliangine
|
CHEMBL483867
CHEMBL517148 CHEMBL463123 |
No. 94 | No. 38 |
|
|||
|
C00011866
|
Tagitinin E
|
C012565
|
No. 687 | No. 38 |
|
|||
|
C00000218
|
Jasmonic acid
/ trans-Jasmonic acid / 3-Oxo-2-(2Z-pentenyl)cyclotentylacetic acid |
CHEMBL445499
CHEMBL449572 |
C011006
|
4 / 1 / 0 | No. 707 | No. 70 |
|
|
|
C00002648
|
Gentisic acid
/ 2,5-Dihydroxybenzoic acid |
CHEMBL1461
|
C010925
|
15 / 6 / 8 | 2 / 1 | No. 817 | No. 81 |
|
|
C00000170
|
trans-Cinnamate
/ trans-Cinnamic acid |
CHEMBL27246
|
5 / 2 / 2 | No. 904 | No. 6 |
|
||
|
C00000580
|
trans-p-Coumaric acid
/ trans-p-Hydroxycinnamic acid |
CHEMBL66879
CHEMBL2336752 |
23 / 13 / 18 | No. 904 | No. 6 |
|
||
|
C00000091
|
trans-Zeatin
|
CHEMBL525239
|
D015026
|
2 / 3 / 2 | 0 / 1 | No. 2879 |
|
|
|
C00011637
|
Helianthol A
/ [R-(E)]-2-Methyl-6-(4-methyl-3-cyclohexen-1-yl)-4,6-heptadien-2-ol |
No. 3871 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000170 C00002648 | 0 / 0 |
| P17516 | Aldo-keto reductase family 1 member C4 | Enzyme | C00000218 C00000580 | 1 / 0 |
| P52895 | Aldo-keto reductase family 1 member C2 | Enzyme | C00000218 C00000580 | 1 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00000170 C00000580 | 1 / 1 |
| Q04828 | Aldo-keto reductase family 1 member C1 | Enzyme | C00000218 C00000580 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00000580 C00002648 | 0 / 1 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00000580 C00002648 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00000170 C00000580 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00000580 C00002648 | 0 / 0 |
| Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00000170 C00000580 | 0 / 0 |
| P42330 | Aldo-keto reductase family 1 member C3 | Enzyme | C00000218 C00000580 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000580 C00002648 | 1 / 2 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000580 C00002648 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00000580 C00002648 | 1 / 2 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000580 | 1 / 8 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00000580 | 0 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000170 | 1 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000091 | 3 / 2 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00002648 | 2 / 2 |
| P22894 | Neutrophil collagenase | M10A | C00002648 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000580 | 0 / 0 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000580 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00002648 | 0 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00002648 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00000580 | 4 / 2 |
| Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00000580 | 3 / 0 |
| P08253 | 72 kDa type IV collagenase | M10A | C00002648 | 1 / 3 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000580 | 0 / 3 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00002648 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002648 | 0 / 0 |
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00000580 | 0 / 0 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00000580 | 0 / 0 |
| P08254 | Stromelysin-1 | M10A | C00002648 | 1 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00000580 | 1 / 1 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00000091 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 2539 | G6PD, G6PD1 | glucose-6-phosphate dehydrogenase (EC:1.1.1.49) |
C00002648
|
| 6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00002648
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #614279 | 46,xy sex reversal 8; srxy8 |
P17516
P52895 |
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #600807 | Asthma, susceptibility to |
Q13093
|
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #147050 | Ige responsiveness, atopic; iger |
Q13093
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #211980 | Lung cancer |
P00533
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #278300 | Xanthinuria, type i |
P47989
|
| KEGG | name | UniProt |
|---|---|---|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
|
| H00022 | Bladder cancer |
P00533
(related)
|
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P08253 (related) |
| H00030 | Cervical cancer |
P00533
(related)
|
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00025 | Penile cancer |
P08253
(related)
P14780 (related) P35354 (related) |
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|