Drymaria diandra
Species
KNApSAcK Entry
| Organism name | Drymaria diandra |
|---|---|
| Genus | Drymaria |
| Family | Caryophyllaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Drymaria cordata |
|---|---|
| Linked NCBI taxonomy ID | 191453 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Caryophyllaceae |
|---|---|
| ID | 3568 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Metabolite list (7)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00043451
|
Diandraflavone
/ (+)-Diandraflavone |
CHEMBL457156
|
No. 1 | No. 15 |
|
|||
|
C00001059
|
Isovitexin
/ Saponaretin / Homovitexin / 6-C-beta-D-Glucopyranosylapigenin / 6-beta-D-Glucopyranosyl-4',5,7-trihydroxyflavone / 6-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL465360
CHEMBL1601394 |
C049772
|
28 / 20 / 19 | No. 22 | No. 15 |
|
|
|
C00006100
|
Torosaflavone A
|
No. 22 | No. 15 |
|
||||
|
C00043472
|
Drymaritin
|
No. 438 |
|
|||||
|
C00000856
|
4-Hydroxybenzoic acid
/ p-Hydroxybenzoic acid |
CHEMBL441343
|
C038193
|
21 / 7 / 16 | 2 / 1 | No. 817 | No. 81 |
|
|
C00002657
|
p-Formylphenol
/ 4-Hydroxybenzaldehyde / p-Hydroxybenzaldehyde |
CHEMBL14193
|
C011483
|
3 / 2 / 2 | No. 2076 |
|
||
|
C00043715
|
Methyl 5-hydroxy-4-oxopentanoate
|
No. 8281 |
|
Human Protein / Gene in interactions
50 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P51649 | Succinate-semialdehyde dehydrogenase, mitochondrial | Oxidoreductase | C00000856 C00002657 | 1 / 1 |
| P80404 | 4-aminobutyrate aminotransferase, mitochondrial | Transferase | C00000856 C00002657 | 1 / 1 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00001059 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00001059 | 1 / 1 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000856 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000856 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00000856 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00001059 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001059 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000856 | 1 / 2 |
| Q9UQ49 | Sialidase-3 | Enzyme | C00000856 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001059 | 1 / 0 |
| Q9HAW7 | UDP-glucuronosyltransferase 1-7 | Enzyme | C00000856 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000856 | 1 / 8 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00000856 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000856 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001059 | 0 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00001059 | 2 / 2 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00000856 | 1 / 2 |
| P14902 | Indoleamine 2,3-dioxygenase 1 | Enzyme | C00002657 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00001059 | 0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00000856 | 0 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00000856 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00001059 | 7 / 3 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00001059 | 1 / 1 |
| P06746 | DNA polymerase beta | Enzyme | C00001059 | 0 / 0 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00000856 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00000856 | 0 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001059 | 0 / 0 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00000856 | 0 / 0 |
| P51580 | Thiopurine S-methyltransferase | Enzyme | C00000856 | 1 / 1 |
| P30989 | Neurotensin receptor type 1 | Neurotensin receptor | C00001059 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001059 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001059 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001059 | 0 / 0 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00000856 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001059 | 0 / 0 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00000856 | 0 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00000856 | 1 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001059 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001059 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00001059 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001059 | 1 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00001059 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00001059 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001059 | 1 / 2 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001059 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001059 | 1 / 4 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001059 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00001059 | 2 / 1 |
2 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 3952 | LEP, LEPD, OB, OBS | leptin |
C00000856
|
| 6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00000856
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (27)
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #114500 | Colorectal cancer; crc |
Q14191
|
| #613163 | Gaba-transaminase deficiency |
P80404
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #211980 | Lung cancer |
P00533
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #271980 | Succinic semialdehyde dehydrogenase deficiency; ssadhd |
P51649
|
| #610460 | Thiopurine s-methyltransferase deficiency |
P51580
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (35)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
|
| H00018 | Gastric cancer |
P00533
(related)
|
| H00022 | Bladder cancer |
P00533
(related)
|
| H00028 | Choriocarcinoma |
P00533
(related)
|
| H00030 | Cervical cancer |
P00533
(related)
|
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H00964 | Thiopurine S-methyltransferase deficiency (TPMT deficiency) |
P51580
(related)
|
| H00835 | Succinic semialdehyde dehydrogenase (SSADH) deficiency |
P51649
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H01257 | GABA-transaminase deficiency |
P80404
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|