Species

KNApSAcK Entry

Organism name Agathis australis
Genus Agathis
Family Araucariaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Agathis australis
Linked NCBI taxonomy ID 58027
Linked level species

Family

Family in NCBI taxonomy Araucariaceae
ID 25664

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Spermatophyta
ID 58024

Metabolite list (11)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00006464 External link 512 Cupressuflavone tetramethyl ether
No. 34 No. 18
C00006453 External link 512 7,7''-Di-O-methylagathisflavone
No. 34 No. 18
C00006456 External link 512 Agathisflavone tetramethyl ether
No. 34 No. 18
C00006463 External link 512 Cupressuflavone 7,4',7''-trimethyl ether
No. 34 No. 18
C00023287 External link 512 Z-Communic acid
/ Elliotinoic acid
/ (Z)-Communic acid
/ cis-Communic acid
CHEMBL498097
CHEMBL1488779
CHEMBL1731589
13 / 14 / 8 No. 143
C00000893 External link 512 Sclarene
No. 165
C00034864 External link 512 Isopimara-7,15-dien-3beta-ol
/ (-)-Isopimara-7,15-dien-3beta-ol
CHEMBL225866
No. 208 No. 48
C00022709 External link 512 Agathalic acid
No. 228
C00041322 External link 512 Agathic acid
CHEMBL457162
C110795
No. 228
C00020130 External link 512 gamma-Muurolene
/ 1beta-Cadina-4,10(15)-diene
No. 283 No. 39
C00031571 External link 512 Agatharesinol
No. 922 No. 24

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00023287 0 / 0
P06746 DNA polymerase beta Enzyme C00023287 0 / 0
P39748 Flap endonuclease 1 Enzyme C00023287 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00023287 7 / 3
Q9Y253 DNA polymerase eta Enzyme C00023287 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00023287 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00023287 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00023287 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00023287 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00023287 4 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00023287 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00023287 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00023287 2 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#114500 Colorectal cancer; crc Q14191
#600274 Frontotemporal dementia; ftd P10636
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (8)

KEGG name UniProt
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)