Species

KNApSAcK Entry

Organism name Delonix regia
Genus Delonix
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Delonix regia
Linked NCBI taxonomy ID 72433
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00006639 External link 512 Pelargonidin 3-rutinoside
No. 1 No. 15
C00002374 External link 512 Chrysanthemin
/ Cyanidin 3-O-glucoside
CHEMBL257839
CHEMBL1197952
C114438
1 / 0 / 1 No. 2 No. 15
C00000931 External link 512 Zeaxanthin
/ all-trans-Zeaxanthin
CHEMBL1357855
CHEMBL2359248
C005881
4 / 2 / 3 1 / 0 No. 26 No. 59
C00001343 External link 512 L-Azetidine 2-carboxylic acid
CHEMBL33592
CHEMBL1165239
CHEMBL1599178
C089382
8 / 14 / 15 No. 1523 No. 1
C00001200 External link 512 Pyruvic acid
CHEMBL1162144
D019289
5 / 2 / 2 10 / 4 No. 2782
C00001161 External link 512 Erythritol
/ meso-Erythritol
CHEMBL349605
CHEMBL402812
D004896
3 / 5 / 5 No. 2923
C00001186 External link 512 Glyoxylic acid
CHEMBL1162545
C031150
1 / 0 / 0 0 / 1 No. 7855

Human Protein / Gene in interactions

21 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O15427 Monocarboxylate transporter 4 Unclassified protein C00001186 C00001200 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001343 0 / 0
P02545 Prelamin-A/C Unclassified protein C00001343 11 / 10
P37840 Alpha-synuclein Unclassified protein C00001161 4 / 2
P00918 Carbonic anhydrase 2 Lyase C00001161 1 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001343 0 / 1
P54132 Bloom syndrome protein Enzyme C00001343 1 / 2
P11473 Vitamin D3 receptor NR1I1 C00000931 2 / 3
O75496 Geminin Unclassified protein C00000931 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00000931 0 / 0
P28907 ADP-ribosyl cyclase 1 Enzyme C00002374 0 / 1
Q16790 Carbonic anhydrase 9 Lyase C00001161 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001343 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001343 0 / 1
Q7Z2H8 Proton-coupled amino acid transporter 1 Unclassified protein C00001343 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00000931 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001343 1 / 0
Q92959 Solute carrier organic anion transporter family member 2A1 Unclassified protein C00001200 1 / 0
O60669 Monocarboxylate transporter 2 Unclassified protein C00001200 0 / 0
Q05BR4 SLC16A10 protein Unclassified protein C00001200 0 / 0
Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO Unclassified protein C00001200 1 / 2

11 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
2950 GSTP1, DFN7, FAEES3, GST3, GSTP, PI glutathione S-transferase pi 1 (EC:2.5.1.18) C00000931
31 ACACA, ACAC, ACACAD, ACC, ACC1, ACCA acetyl-CoA carboxylase alpha (EC:6.4.1.2 6.3.4.14) C00001200
1487 CTBP1, BARS C-terminal binding protein 1 C00001200
1488 CTBP2 C-terminal binding protein 2 C00001200
1586 CYP17A1, CPT7, CYP17, P450C17, S17AH cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30) C00001200
14103 C00001200
2516 NR5A1, AD4BP, ELP, FTZ1, FTZF1, POF7, SF-1, SF1, SPGF8, SRXY3 nuclear receptor subfamily 5, group A, member 1 C00001200
10891 PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha C00001200
23411 SIRT1, SIR2L1 sirtuin 1 C00001200
6566 SLC16A1, HHF7, MCT, MCT1 solute carrier family 16 (monocarboxylate transporter), member 1 C00001200
6647 SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer superoxide dismutase 1, soluble (EC:1.15.1.1) C00001200

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (23)

OMIM preferred title UniProt
#210900 Bloom syndrome; blm P54132
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#127750 Dementia, lewy body; dlb P37840
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#612938 Growth retardation, developmental delay, coarse facies, and early death; gdfd Q9C0B1
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#614441 Hypertrophic osteoarthropathy, primary, autosomal recessive, 2; phoar2 Q92959
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#275210 Restrictive dermopathy, lethal P02545
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (26)

KEGG name UniProt
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00005 Chronic lymphocytic leukemia (CLL) P28907 (marker)
H01171 Poor drug metabolism (PM) P33261 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00021 Renal cell carcinoma Q16790 (marker)
H00409 Type II diabetes mellitus Q9C0B1 (related)
H00926 Growth retardation, developmental delay, coarse facies, and early death Q9C0B1 (related)

Diseases related to CTD interactions

5 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D007669 Kidney Calculi C00001186
D006943 Hyperglycemia C00001200
D028361 Mitochondrial Diseases C00001200
D009135 Muscular Diseases C00001200
D009336 Necrosis C00001200