Vaccinium macrocarpon
Species
KNApSAcK Entry
| Organism name | Vaccinium macrocarpon |
|---|---|
| Genus | Vaccinium |
| Family | Ericaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Vaccinium macrocarpon |
|---|---|
| Linked NCBI taxonomy ID | 13750 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Ericaceae |
|---|---|
| ID | 4345 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (7)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00006679
|
Peonidin 3-arabinoside
|
No. 2 | No. 15 |
|
||||
|
C00006680
|
Peonidin galactoside
/ Peonidin 3-galactoside / Peonidin 3-O-beta-D-galactopyranoside |
CHEMBL1784263
|
No. 2 | No. 15 |
|
|||
|
C00003558
|
Ursolic acid
|
CHEMBL297810
CHEMBL56048 CHEMBL300594 CHEMBL169 CHEMBL176234 CHEMBL491715 CHEMBL1316667 CHEMBL1555307 CHEMBL1593360 CHEMBL1979720 |
C005466
|
47 / 26 / 33 | 15 / 12 | No. 13 | No. 51 |
|
|
C00009077
|
Procyanidin B2
/ Epicathechin-(4beta->8)-epicathechin |
CHEMBL38714
CHEMBL81753 CHEMBL504937 CHEMBL501490 CHEMBL447373 CHEMBL1253314 CHEMBL1590914 |
C479580
|
20 / 7 / 8 | 10 / 0 | No. 16 | No. 19 |
|
|
C00003776
|
Lutein
/ (all-E)-Lutein / all-trans-(+)-Xanthophyll / (3R,3'R,6'R)-beta,epsilon-Carotene-3,3'-diol |
CHEMBL173929
CHEMBL172477 CHEMBL1559643 CHEMBL1979448 |
D014975
|
4 / 2 / 3 | 7 / 2 | No. 26 | No. 59 |
|
|
C00000956
|
(-)-Epicatechin
|
CHEMBL80941
CHEMBL311498 CHEMBL129482 CHEMBL200715 CHEMBL206452 CHEMBL583912 |
85 / 58 / 54 | No. 52 | No. 14 |
|
||
|
C00000934
|
zeta-Carotene
|
No. 97 | No. 59 |
|
Human Protein / Gene in interactions
119 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000956 C00003558 C00009077 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000956 C00003558 C00009077 | 0 / 1 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000956 C00003558 C00003776 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000956 C00003558 C00009077 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000956 C00003558 C00009077 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000956 C00003558 C00009077 | 0 / 1 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000956 C00003558 | 1 / 2 |
| P05129 | Protein kinase C gamma type | Alpha | C00000956 C00009077 | 1 / 1 |
| P06746 | DNA polymerase beta | Enzyme | C00000956 C00003558 | 0 / 0 |
| Q05655 | Protein kinase C delta type | Delta | C00000956 C00009077 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00000956 C00009077 | 0 / 0 |
| O94806 | Serine/threonine-protein kinase D3 | Pkd | C00000956 C00009077 | 0 / 0 |
| Q02156 | Protein kinase C epsilon type | Eta | C00000956 C00009077 | 0 / 0 |
| Q04759 | Protein kinase C theta type | Delta | C00000956 C00009077 | 0 / 1 |
| Q05513 | Protein kinase C zeta type | Iota | C00000956 C00009077 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000956 C00003558 | 0 / 3 |
| O00255 | Menin | Unclassified protein | C00000956 C00003558 | 2 / 5 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000956 C00003776 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00000956 C00003558 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000956 C00003558 | 0 / 0 |
| P05771 | Protein kinase C beta type | Alpha | C00000956 C00009077 | 0 / 0 |
| P24723 | Protein kinase C eta type | Eta | C00000956 C00009077 | 1 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00000956 C00009077 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00000956 C00003558 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000956 C00009077 | 3 / 3 |
| P41743 | Protein kinase C iota type | Iota | C00000956 C00009077 | 0 / 0 |
| P18433 | Receptor-type tyrosine-protein phosphatase alpha | Receptor tyrosine-protein phosphatase | C00003558 C00009077 | 0 / 0 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000956 C00003558 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000956 C00003558 | 0 / 0 |
| Q15139 | Serine/threonine-protein kinase D1 | Pkd | C00000956 C00009077 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00000956 C00003776 | 2 / 3 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00000956 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00000956 | 1 / 2 |
| P10586 | Receptor-type tyrosine-protein phosphatase F | Receptor tyrosine-protein phosphatase | C00003558 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00000956 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00000956 | 0 / 0 |
| Q9Y3R4 | Sialidase-2 | Enzyme | C00000956 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000956 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000956 | 0 / 0 |
| P28845 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | Enzyme | C00003558 | 1 / 1 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00000956 | 1 / 2 |
| Q9UQL6 | Histone deacetylase 5 | Hydrolase | C00003558 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00000956 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00003558 | 0 / 0 |
| P07998 | Ribonuclease pancreatic | Enzyme | C00000956 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000956 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00003776 | 0 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00000956 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00003558 | 0 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00000956 | 0 / 0 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00003558 | 0 / 0 |
| P07711 | Cathepsin L1 | C1A | C00000956 | 0 / 0 |
| Q04206 | Transcription factor p65 | Transcription Factor | C00003558 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00000956 | 1 / 1 |
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00000956 | 0 / 0 |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00000956 | 3 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00003558 | 0 / 0 |
| P49327 | Fatty acid synthase | Transferase | C00000956 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00000956 | 4 / 2 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00003558 | 2 / 2 |
| P04745 | Alpha-amylase 1 | Enzyme | C00000956 | 0 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00003558 | 0 / 0 |
| O15379 | Histone deacetylase 3 | Hydrolase | C00003558 | 0 / 0 |
| P02768 | Serum albumin | Secreted protein | C00000956 | 0 / 0 |
| P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00000956 | 2 / 3 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000956 | 0 / 0 |
| P10696 | Alkaline phosphatase, placental-like | Enzyme | C00000956 | 0 / 1 |
| P56817 | Beta-secretase 1 | A1A | C00000956 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000956 | 1 / 2 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00000956 | 0 / 1 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00003558 | 3 / 1 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000956 | 2 / 2 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00000956 | 5 / 2 |
| P00374 | Dihydrofolate reductase | Oxidoreductase | C00000956 | 1 / 1 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00000956 | 0 / 0 |
| P56524 | Histone deacetylase 4 | Hydrolase | C00003558 | 1 / 1 |
| P23467 | Receptor-type tyrosine-protein phosphatase beta | Receptor tyrosine-protein phosphatase | C00009077 | 0 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000956 | 1 / 1 |
| P30305 | M-phase inducer phosphatase 2 | Ser_Thr_Tyr | C00003558 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000956 | 3 / 2 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00003558 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00003558 | 11 / 10 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000956 | 0 / 0 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00000956 | 1 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00003558 | 0 / 0 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00000956 | 5 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000956 | 4 / 3 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00003558 | 0 / 0 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00000956 | 0 / 0 |
| P17706 | Tyrosine-protein phosphatase non-receptor type 2 | Tyr | C00003558 | 0 / 1 |
| Q9UBN7 | Histone deacetylase 6 | Hydrolase | C00003558 | 0 / 0 |
| P29350 | Tyrosine-protein phosphatase non-receptor type 6 | Tyr | C00003558 | 0 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00000956 | 1 / 1 |
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00003558 | 1 / 1 |
| P10415 | Apoptosis regulator Bcl-2 | Other cytosolic protein | C00000956 | 0 / 7 |
| P23469 | Receptor-type tyrosine-protein phosphatase epsilon | Receptor tyrosine-protein phosphatase | C00003558 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00000956 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000956 | 0 / 0 |
| Q8TDU6 | G-protein coupled bile acid receptor 1 | Steroid-like ligand receptor | C00003558 | 0 / 0 |
| P24666 | Low molecular weight phosphotyrosine protein phosphatase | Tyr | C00003558 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000956 | 1 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00003558 | 1 / 0 |
| P28907 | ADP-ribosyl cyclase 1 | Enzyme | C00000956 | 0 / 1 |
| Q8N1Q1 | Carbonic anhydrase 13 | Lyase | C00000956 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00003558 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00003558 | 1 / 4 |
| Q13547 | Histone deacetylase 1 | Hydrolase | C00003558 | 0 / 0 |
| P52209 | 6-phosphogluconate dehydrogenase, decarboxylating | Enzyme | C00000956 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00000956 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000956 | 0 / 0 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000956 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00000956 | 1 / 1 |
| Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00000956 | 3 / 0 |
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00003558 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00000956 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00000956 | 4 / 1 |
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00000956 | 3 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00003558 | 0 / 0 |
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00000956 | 0 / 0 |
26 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00003558
C00003776
C00009077
|
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00003558
C00009077
|
| 7153 | TOP2A, TOP2, TP2A | topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) |
C00003558
C00009077
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00003558
C00003776
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00003558
C00009077
|
| 7150 | TOP1, TOPI | topoisomerase (DNA) I (EC:5.99.1.2) |
C00003558
|
| 9131 | AIFM1, AIF, CMTX4, COWCK, COXPD6, PDCD8 | apoptosis-inducing factor, mitochondrion-associated, 1 |
C00003558
|
| 1557 | CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19 | cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00003558
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00003558
|
| 4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) |
C00003558
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00003558
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00003558
|
| 7040 | TGFB1, CED, DPD1, LAP, TGFB, TGFbeta | transforming growth factor, beta 1 |
C00003558
|
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00003558
|
| 578 | BAK1, BAK, BAK-LIKE, BCL2L7, CDN1 | BCL2-antagonist/killer 1 |
C00003558
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00009077
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00009077
|
| 2932 | GSK3B | glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) |
C00009077
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00009077
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00009077
|
| 4240 | MFGE8, BA46, EDIL1, HMFG, HsT19888, MFG-E8, MFGM, OAcGD3S, SED1, SPAG10, hP47 | milk fat globule-EGF factor 8 protein |
C00009077
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00003776
|
| 847 | CAT | catalase (EC:1.11.1.6) |
C00003776
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00003776
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00003776
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00003776
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (79)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #218030 | Apparent mineralocorticoid excess; ame |
P80365
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #600807 | Asthma, susceptibility to |
Q13093
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #600430 | Brachydactyly-mental retardation syndrome; bdmr |
P56524
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #604931 | Cortisone reductase deficiency 1; cortrd1 |
P28845
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #114550 | Hepatocellular carcinoma |
P08581
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #146300 | Hypophosphatasia, adult |
P05186
|
| #241510 | Hypophosphatasia, childhood |
P05186
|
| #241500 | Hypophosphatasia, infantile |
P05186
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #147050 | Ige responsiveness, atopic; iger |
Q13093
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613839 | Megaloblastic anemia due to dihydrofolate reductase deficiency |
P00374
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #605074 | Renal cell carcinoma, papillary, 1; rccp1 |
P08581
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #605361 | Spinocerebellar ataxia 14; sca14 |
P05129
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601367 | Stroke, ischemic |
P00734
P24723 |
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (72)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
P08581 (related) Q16790 (marker) |
| H01197 | Dihydrofolate reductase (DHFR) deficiency |
P00374
(related)
|
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
P05129
(related)
Q9NUW8 (related) |
| H00213 | Hypophosphatasia |
P05186
(related)
|
| H00018 | Gastric cancer |
P08581
(related)
P10415 (related) |
| H00046 | Cholangiocarcinoma |
P08581
(related)
P35354 (related) |
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P10415
(related)
P28907 (marker) |
| H00013 | Small cell lung cancer |
P10415
(related)
|
| H00028 | Choriocarcinoma |
P10415
(related)
|
| H00030 | Cervical cancer |
P10415
(related)
|
| H00041 | Kaposi's sarcoma |
P10415
(related)
|
| H00054 | Nasopharyngeal cancer |
P10415
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00023 | Testicular cancer |
P10696
(marker)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P11511
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00408 | Type I diabetes mellitus |
P17706
(related)
Q04759 (related) |
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01111 | Cortisone reductase deficiency (CRD) |
P28845
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H00561 | Brachydacytly-mental retardation syndrome and Smith-Magenis syndrome |
P56524
(related)
|
| H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
Diseases related to CTD interactions
14 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D001284 | Atrophy |
C00003558
|
| D006528 | Carcinoma, Hepatocellular |
C00003558
|
| D002471 | Cell Transformation, Neoplastic |
C00003558
|
| D003921 | Diabetes Mellitus, Experimental |
C00003558
|
| D006943 | Hyperglycemia |
C00003558
|
| D006949 | Hyperlipidemias |
C00003558
|
| D006965 | Hyperplasia |
C00003558
|
| D007249 | Inflammation |
C00003558
|
| D008103 | Liver Cirrhosis |
C00003558
|
| D017202 | Myocardial Ischemia |
C00003558
|
| D009369 | Neoplasms |
C00003558
|
| D012878 | Skin Neoplasms |
C00003558
|
| D007939 | Leukemia L1210 |
C00003776
|
| D014605 | Uveitis |
C00003776
|