Annona reticulata

• Index
• Plant Species
• Natural Activity
• Metabolite list (25)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Annona reticulata
Genus	Annona
Family	Annonaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Annona reticulata
Linked NCBI taxonomy ID	301862
Linked level	species

Family

Family in NCBI taxonomy	Annonaceae
ID	22140

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Magnoliophyta
ID	3398

Natural Activity

List (13)

Species	Activity
Annona reticulata L.	Anthelmintic
Annona reticulata L.	Anticancer
Annona reticulata L.	Antiinflammatory
Annona reticulata L.	Antineoplastic
Annona reticulata L.	Antitumor
Annona reticulata L.	Astringent
Annona reticulata L.	Cytotoxic
Annona reticulata L.	Insecticide
Annona reticulata L.	Pediculicide
Annona reticulata L.	Poison
Annona reticulata L.	Purgative
Annona reticulata L.	Tonic
Annona reticulata L.	Vermifuge

Metabolite list (25)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001302	Bullatacinone	CHEMBL28898 CHEMBL349802 CHEMBL448053 CHEMBL500765 CHEMBL1967501 CHEMBL1981927	C061021			No. 6	No. 70
C00001323	Squamocin	CHEMBL41177 CHEMBL502366 CHEMBL453405 CHEMBL452936	C059660			No. 6	No. 70
C00049020	trans-Murisolinone					No. 6	No. 70
C00049019	trans-Isomurisolenin					No. 6	No. 70
C00048967	cis-Murisolinone					No. 6	No. 70
C00048966	cis-Isomurisolenin					No. 6	No. 70
C00048965	cis-Bullatacinone	CHEMBL28898 CHEMBL349802 CHEMBL448053 CHEMBL500765 CHEMBL1967501 CHEMBL1981927				No. 6	No. 70
C00048955	Annoreticuin-9-one	CHEMBL447923 CHEMBL505178 CHEMBL503350 CHEMBL449247				No. 6	No. 70
C00044198	Isoannoreticuin	CHEMBL451459				No. 6	No. 70
C00044048	10-Hydroxy-asimicin / (+)-10-Hydroxy-asimicin	CHEMBL443639 CHEMBL509800 CHEMBL447889 CHEMBL443955 CHEMBL2007510				No. 6	No. 70
C00038662	Bullatacin / (+)-Bullatacin	CHEMBL13710 CHEMBL61332 CHEMBL68179 CHEMBL142918 CHEMBL453675 CHEMBL503360 CHEMBL453496 CHEMBL454744 CHEMBL501110 CHEMBL451402 CHEMBL506914 CHEMBL446085 CHEMBL509939 CHEMBL508255 CHEMBL499188 CHEMBL1996175 CHEMBL1999460 CHEMBL2007355				No. 6	No. 70
C00027153	Norcorydine / (+)-Norcorydine	CHEMBL494053				No. 20	No. 4
C00001861	Glaucine / S-(+)-Glaucine / O,O-Dimethylisoboldine	CHEMBL36536 CHEMBL228082		14 / 8 / 6		No. 20	No. 4
C00025827	Corydine / Glaucentrin / (+)-Corydine / Glaucentrine	CHEMBL489524 CHEMBL2002847	C067341	1 / 0 / 0		No. 20	No. 4
C00001928	Xylopine / (-)-Xylopine	CHEMBL227689 CHEMBL452201	C062700			No. 20	No. 4
C00025231	Asimilobine / (-)-Asimilobine	CHEMBL389271 CHEMBL469423	C054614	1 / 1 / 0		No. 20	No. 4
C00001807	Anonaine / (-)-Anonaine / (R)-Annonaine	CHEMBL401798	C098138	1 / 0 / 0		No. 20	No. 4
C00025319	Oxoxylopin / Oxoxylopine / Lanuginosine	CHEMBL389400		1 / 4 / 2		No. 74
C00025995	Oxonantenine	CHEMBL1270949				No. 74
C00001878	Liriodenine / Oxoushinsunine / Spermatheridine	CHEMBL37736	C026980	5 / 3 / 1		No. 74
C00001910	Reticuline / (+)-Reticuline	CHEMBL235212 CHEMBL401501 CHEMBL464734	C003298	1 / 0 / 0		No. 345	No. 4
C00044145	Dieporeticanin 1					No. 421
C00044146	Dieporeticanin 2					No. 421
C00044147	Dieporeticenin					No. 421
C00044294	Reticulatamone					No. 3105

Human Protein / Gene in interactions

22 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q14761	Protein tyrosine phosphatase receptor type C-associated protein	Enzyme	C00001807 C00001861 C00001878	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00001861	0 / 0
P24941	Cyclin-dependent kinase 2	Cdc2	C00025827	0 / 0
P30926	Neuronal acetylcholine receptor subunit beta-4	CHRN beta	C00001878	0 / 0
P32297	Neuronal acetylcholine receptor subunit alpha-3	CHRN alpha	C00001878	1 / 0
P17787	Neuronal acetylcholine receptor subunit beta-2	CHRN beta	C00001878	1 / 1
P43681	Neuronal acetylcholine receptor subunit alpha-4	CHRN alpha	C00001878	1 / 1
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00001861	1 / 0
Q9BQF6	Sentrin-specific protease 7	Enzyme	C00001861	0 / 0
Q9GZR1	Sentrin-specific protease 6	Enzyme	C00001861	0 / 0
Q96LD8	Sentrin-specific protease 8	Enzyme	C00001861	0 / 0
P42574	Caspase-3	C14	C00001861	0 / 0
O75496	Geminin	Unclassified protein	C00001861	0 / 0
P00734	Prothrombin	S1A	C00025319	4 / 2
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00001861	3 / 3
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001861	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00025231	1 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00001910	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00001861	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00001861	4 / 3
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00001861	0 / 0
P43351	DNA repair protein RAD52 homolog	Unclassified protein	C00001861	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions