Papaver caucasicum
Species
KNApSAcK Entry
| Organism name | Papaver caucasicum |
|---|---|
| Genus | Papaver |
| Family | Papaveraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Papaver |
|---|---|
| Linked NCBI taxonomy ID | 3468 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Papaveraceae |
|---|---|
| ID | 3465 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Metabolite list (13)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00027576
|
Nuciferine
/ D-(-)-Nuciferine |
CHEMBL464529
|
C008692
|
0 / 1 | No. 20 | No. 4 |
|
|
|
C00027441
|
Nornuciferine
/ Sanjoinine Ia / Daechualkaloid E |
CHEMBL36496
CHEMBL325416 CHEMBL1164391 |
1 / 0 / 0 | No. 20 | No. 4 |
|
||
|
C00001801
|
Amurensine
|
No. 37 | No. 4 |
|
||||
|
C00001878
|
Liriodenine
/ Oxoushinsunine / Spermatheridine |
CHEMBL37736
|
C026980
|
5 / 3 / 1 | No. 74 |
|
||
|
C00025935
|
Lysicamine
/ Oxonuciferine |
CHEMBL510090
|
C069090
|
No. 74 |
|
|||
|
C00025458
|
Papaverrubine B
/ O-Methylporphyroxine |
No. 305 |
|
|||||
|
C00025457
|
Papaverrubin A
/ Papaverrubine A / N-Demethylisorheadine |
No. 305 |
|
|||||
|
C00025459
|
Papaverrubine C
/ Epiporphyroxine / 14-Epiporphyroxine |
No. 305 |
|
|||||
|
C00025461
|
Papaverrubine E
|
No. 305 |
|
|||||
|
C00025460
|
Porphyroxine
/ Papaverrubine D |
No. 305 |
|
|||||
|
C00001810
|
Armepavine
/ (-)-Armepavine / (R)-(-)-Armepavine |
CHEMBL451722
CHEMBL1186477 CHEMBL1186510 |
7 / 5 / 3 | No. 345 | No. 4 |
|
||
|
C00001916
|
Salutaridine
/ (+)-Salutaridine |
CHEMBL402782
CHEMBL404097 |
C009270
|
3 / 4 / 2 | No. 426 | No. 4 |
|
|
|
C00001886
|
Mecambrine
/ (-)-Fugapavine / (-)-Mecambrine |
No. 688 |
|
Human Protein / Gene in interactions
15 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q14761 | Protein tyrosine phosphatase receptor type C-associated protein | Enzyme | C00001878 C00027441 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00001810 | 2 / 0 |
| P32297 | Neuronal acetylcholine receptor subunit alpha-3 | CHRN alpha | C00001878 | 1 / 0 |
| P17787 | Neuronal acetylcholine receptor subunit beta-2 | CHRN beta | C00001878 | 1 / 1 |
| P43681 | Neuronal acetylcholine receptor subunit alpha-4 | CHRN alpha | C00001878 | 1 / 1 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00001916 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001810 | 0 / 0 |
| P30926 | Neuronal acetylcholine receptor subunit beta-4 | CHRN beta | C00001878 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00001916 | 4 / 2 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001810 | 3 / 3 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00001916 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001810 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001810 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001810 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001810 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (12)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #600513 | Epilepsy, nocturnal frontal lobe, 1; enfl1 |
P43681
|
| #605375 | Epilepsy, nocturnal frontal lobe, 3; enfl3 |
P17787
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #612052 | Smoking as a quantitative trait locus 3; sqtl3 |
P32297
|
| #601367 | Stroke, ischemic |
P00734
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
KEGG DISEASE (6)
| KEGG | name | UniProt |
|---|---|---|
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00807 | Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) |
P17787
(related)
P43681 (related) |
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|