Stephania pierii

• Index
• Plant Species
• Metabolite list (11)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Stephania pierii
Genus	Stephania
Family	Menispermaceae
Kingdom	Plantae

---

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Stephania
Linked NCBI taxonomy ID	147243
Linked level	genus

Family

Family in NCBI taxonomy	Menispermaceae
ID	3455

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	eudicotyledons
ID	71240

Metabolite list (11)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00028657	N-Demethylcycleanine					No. 10	No. 4
C00027728	2'-Norisotetrandrine					No. 10	No. 4
C00025260	2-Norberbamine / (+)-2-Norberbamine / 2-Demethylberbamine					No. 10	No. 4
C00025266	Isosinomenin A / Isotetrandrine / Isosinomenine A / O-Methylberbamine / (+)-Isotetrandrine / O,O-Dimethylobamegine / O,O'-Dimethylobamegine / O,O-Dimethylstepholine / O,O'-Dimethylstepholine					No. 10	No. 4
C00025310	Homoaromoline / (+)-Homoaromoline / (+)-Thalrugosamine	CHEMBL507220 CHEMBL503522 CHEMBL509855 CHEMBL1185978				No. 10	No. 4
C00025739	2-Norisotetrandrine	CHEMBL450175				No. 10	No. 4
C00025604	Cycleanine / (-)-Cycleanine	CHEMBL1711244 CHEMBL1983719	C037098	7 / 1 / 1		No. 10	No. 4
C00001872	Isocorydine / (+)-Isocorydine / L-(+)-Isocorydine / (S)-(+)-Isocorydine	CHEMBL489525 CHEMBL1376826		14 / 7 / 10		No. 20	No. 4
C00027522	Berbamunine / (+)-Berbamunine	CHEMBL1187468				No. 89	No. 4
C00025812	Coclaurine / (S)-Coclaurine / (-)-Coclaurine	CHEMBL256448 CHEMBL453291 CHEMBL446211	C004690	8 / 17 / 10		No. 253	No. 4
C00001910	Reticuline / (+)-Reticuline	CHEMBL235212 CHEMBL401501 CHEMBL464734	C003298	1 / 0 / 0		No. 345	No. 4

Human Protein / Gene in interactions

26 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00001872 C00025604 C00025812	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00001872 C00025812	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001872 C00025812	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00001910	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00025604	0 / 0
P24941	Cyclin-dependent kinase 2	Cdc2	C00001872	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00001872	0 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00001872	0 / 0
P14618	Pyruvate kinase PKM	Enzyme	C00025812	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00025604	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00025812	7 / 3
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001872	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00001872	3 / 3
P04062	Glucosylceramidase	Enzyme	C00025812	6 / 4
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001872	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001872	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00025604	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00025604	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00025812	4 / 3
Q99700	Ataxin-2	Unclassified protein	C00025604	1 / 1
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00025812	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00001872	1 / 0
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00025604	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00001872	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00001872	1 / 4
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001872	1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions