| Organism name | Pinellia pedatisecta |
|---|---|
| Genus | Pinellia |
| Family | Araceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Pinellia pedatisecta |
|---|---|
| Linked NCBI taxonomy ID | 199222 |
| Linked level | species |
| Family in NCBI taxonomy | Araceae |
|---|---|
| ID | 4454 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | Liliopsida |
|---|---|
| ID | 4447 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00003672
|
Sitosterol
/ beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol |
CHEMBL221542
CHEMBL1398443 CHEMBL1875388 |
17 / 19 / 12 | No. 53 | No. 11 |
|
||
|
C00001233
|
Palmitic acid
|
CHEMBL82293
|
D019308
|
16 / 8 / 8 | 35 / 1 | No. 184 | No. 68 |
|
|
C00026537
|
Norharman
/ Carbazoline / beta-Carboline / 2-Azacarbazole / 2,9-Diazafluorene |
CHEMBL275224
|
C010262
|
50 / 17 / 8 | 8 / 1 | No. 1889 | No. 4 |
|
|
C00001513
|
Uracil
|
CHEMBL566
|
D014498
|
2 / 1 / 1 | 1 / 8 | No. 3873 |
|
|
|
C00028811
|
Pedatisectine D
|
No. 6135 |
|
|||||
|
C00000209
|
Vitamin B
/ Nicotinamide |
CHEMBL1140
|
D009536
|
96 / 36 / 31 | 24 / 28 | No. 8036 | No. 1 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| O75496 | Geminin | Unclassified protein | C00000209 C00001233 C00001513 C00026537 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00000209 C00001233 C00003672 | 1 / 1 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00000209 C00001233 | 0 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000209 C00003672 | 1 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000209 C00003672 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000209 C00003672 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000209 C00003672 | 0 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000209 C00003672 | 0 / 1 |
| P08183 | Multidrug resistance protein 1 | drug | C00001233 C00003672 | 1 / 0 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00001233 C00003672 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00000209 C00026537 | 0 / 0 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00001233 | 0 / 0 |
| P15090 | Fatty acid-binding protein, adipocyte | Other cytosolic protein | C00001233 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00003672 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00000209 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00000209 | 0 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00000209 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00000209 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00000209 | 2 / 2 |
| O14965 | Aurora kinase A | Aur | C00026537 | 0 / 0 |
| P05413 | Fatty acid-binding protein, heart | Other cytosolic protein | C00001233 | 0 / 0 |
| P08246 | Neutrophil elastase | S1A | C00000209 | 2 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00003672 | 3 / 2 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000209 | 1 / 2 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00000209 | 0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00000209 | 1 / 1 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00000209 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00000209 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00000209 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00000209 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00000209 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00000209 | 0 / 0 |
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00026537 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00000209 | 2 / 2 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00000209 | 0 / 0 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00026537 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00000209 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00000209 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000209 | 0 / 3 |
| Q00535 | Cyclin-dependent kinase 5 | Cdk5 | C00026537 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000209 | 1 / 8 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00001233 | 0 / 0 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00000209 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000209 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00000209 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00000209 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00000209 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00000209 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00000209 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00000209 | 1 / 1 |
| O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | Other serine/threonine protein kinase | C00026537 | 0 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00000209 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00000209 | 1 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00026537 | 0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00000209 | 0 / 0 |
| Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | Enzyme | C00000209 | 0 / 0 |
| P14902 | Indoleamine 2,3-dioxygenase 1 | Enzyme | C00026537 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00000209 | 0 / 0 |
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00026537 | 0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00000209 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00000209 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00000209 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00000209 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00000209 | 1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00000209 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00000209 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00000209 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00000209 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00000209 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00000209 | 1 / 0 |
| P12104 | Fatty acid-binding protein, intestinal | Other cytosolic protein | C00001233 | 0 / 0 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00003672 | 0 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00000209 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00000209 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00000209 | 1 / 0 |
| P09874 | Poly [ADP-ribose] polymerase 1 | Enzyme | C00000209 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00000209 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00000209 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00026537 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00001233 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00003672 | 4 / 2 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00000209 | 0 / 0 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00000209 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00000209 | 0 / 0 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00001233 | 2 / 2 |
| P14679 | Tyrosinase | Oxidoreductase | C00003672 | 4 / 2 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00000209 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00000209 | 2 / 0 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00000209 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00000209 | 1 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00000209 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00000209 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00000209 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00000209 | 0 / 0 |
| O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha | Other serine/threonine protein kinase | C00026537 | 1 / 1 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00001233 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00000209 | 1 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000209 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00000209 | 2 / 1 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003672 | 2 / 0 |
| Q01469 | Fatty acid-binding protein, epidermal | Other cytosolic protein | C00001233 | 0 / 0 |
| Q9NTG7 | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | Enzyme | C00000209 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00026537 | 2 / 2 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00026537 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00000209 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00026537 | 4 / 1 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00000209 | 1 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00000209 | 1 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00000209 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00000209 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00000209 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00000209 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00000209 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00000209 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00000209 | 0 / 0 |
| O60603 | Toll-like receptor 2 | Membrane receptor | C00001233 | 1 / 1 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00003672 | 0 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00000209 | 0 / 0 |
| Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | Enzyme | C00000209 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00026537 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00001233 | 3 / 4 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00000209 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00000209 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00000209 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00000209 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00000209 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00000209 | 1 / 1 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00000209 | 0 / 1 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00000209 | 0 / 0 |
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00003672 | 1 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00026537 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00026537 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00003672 | 1 / 1 |
| Q05513 | Protein kinase C zeta type | Iota | C00026537 | 0 / 0 |
| Q04759 | Protein kinase C theta type | Delta | C00026537 | 0 / 1 |
| Q02156 | Protein kinase C epsilon type | Eta | C00026537 | 0 / 0 |
| O94806 | Serine/threonine-protein kinase D3 | Pkd | C00026537 | 0 / 0 |
| Q05655 | Protein kinase C delta type | Delta | C00026537 | 0 / 0 |
| P05129 | Protein kinase C gamma type | Alpha | C00026537 | 1 / 1 |
| P05771 | Protein kinase C beta type | Alpha | C00026537 | 0 / 0 |
| P24723 | Protein kinase C eta type | Eta | C00026537 | 1 / 0 |
| P41743 | Protein kinase C iota type | Iota | C00026537 | 0 / 0 |
| Q15139 | Serine/threonine-protein kinase D1 | Pkd | C00026537 | 0 / 0 |
| Q9UN88 | Gamma-aminobutyric acid receptor subunit theta | GABA-A theta | C00026537 | 0 / 0 |
| P28472 | Gamma-aminobutyric acid receptor subunit beta-3 | GABA-A beta | C00026537 | 1 / 0 |
| P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | GABA-A alpha | C00026537 | 1 / 1 |
| P48169 | Gamma-aminobutyric acid receptor subunit alpha-4 | GABA-A alpha | C00026537 | 0 / 0 |
| O14764 | Gamma-aminobutyric acid receptor subunit delta | GABA-A delta | C00026537 | 1 / 1 |
| P31644 | Gamma-aminobutyric acid receptor subunit alpha-5 | GABA-A alpha | C00026537 | 0 / 0 |
| Q99928 | Gamma-aminobutyric acid receptor subunit gamma-3 | GABA-A gamma | C00026537 | 0 / 0 |
| P78334 | Gamma-aminobutyric acid receptor subunit epsilon | GABA-A epsilon | C00026537 | 0 / 0 |
| Q8N1C3 | Gamma-aminobutyric acid receptor subunit gamma-1 | GABA-A gamma | C00026537 | 0 / 0 |
| P34903 | Gamma-aminobutyric acid receptor subunit alpha-3 | GABA-A alpha | C00026537 | 0 / 0 |
| O00591 | Gamma-aminobutyric acid receptor subunit pi | GABA-A pi | C00026537 | 0 / 0 |
| P47870 | Gamma-aminobutyric acid receptor subunit beta-2 | GABA-A beta | C00026537 | 0 / 0 |
| P18507 | Gamma-aminobutyric acid receptor subunit gamma-2 | GABA-A gamma | C00026537 | 4 / 2 |
| P18505 | Gamma-aminobutyric acid receptor subunit beta-1 | GABA-A beta | C00026537 | 0 / 0 |
| Q16445 | Gamma-aminobutyric acid receptor subunit alpha-6 | GABA-A alpha | C00026537 | 0 / 0 |
| P47869 | Gamma-aminobutyric acid receptor subunit alpha-2 | GABA-A alpha | C00026537 | 1 / 0 |
| P22694 | cAMP-dependent protein kinase catalytic subunit beta | Pka | C00026537 | 0 / 0 |
| P17612 | cAMP-dependent protein kinase catalytic subunit alpha | Pka | C00026537 | 0 / 0 |
| P22612 | cAMP-dependent protein kinase catalytic subunit gamma | Pka | C00026537 | 0 / 0 |
| P68400 | Casein kinase II subunit alpha | Ck2 | C00026537 | 0 / 0 |
| P19784 | Casein kinase II subunit alpha' | Ck2 | C00026537 | 0 / 0 |
| P67870 | Casein kinase II subunit beta | REG serine/threonine protein kinase family | C00026537 | 0 / 0 |
| Q9NXA8 | NAD-dependent protein deacylase sirtuin-5, mitochondrial | Enzyme | C00000209 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00001513 | 1 / 1 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00000209
C00001233
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00000209
C00001513
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00000209
C00001233
|
| 10891 | PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
C00000209
C00001233
|
| 3630 | INS, IDDM2, ILPR, IRDN, MODY10 | insulin |
C00000209
C00001233
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00000209
C00001233
|
| 5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) |
C00001233
|
| 4129 | MAOB | monoamine oxidase B (EC:1.4.3.4) |
C00026537
|
| 31 | ACACA, ACAC, ACACAD, ACC, ACC1, ACCA | acetyl-CoA carboxylase alpha (EC:6.4.1.2 6.3.4.14) |
C00000209
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00026537
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00000209
|
| 6364 | CCL20, CKb4, LARC, MIP-3-alpha, MIP-3a, MIP3A, SCYA20, ST38 | chemokine (C-C motif) ligand 20 |
C00000209
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00000209
|
| 1978 | EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I | eukaryotic translation initiation factor 4E binding protein 1 |
C00000209
|
| 2152 | F3, CD142, TF, TFA | coagulation factor III (thromboplastin, tissue factor) |
C00000209
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00000209
|
| 3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00000209
|
| 1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) |
C00026537
|
| 1565 | CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 | cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) |
C00026537
|
| 389692 | MAFA, RIPE3b1, hMafA | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A |
C00000209
|
| 4193 | MDM2, ACTFS, HDMX, hdm2 | MDM2 oncogene, E3 ubiquitin protein ligase |
C00000209
|
| 2475 | MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1 | mechanistic target of rapamycin (serine/threonine kinase) (EC:2.7.11.1) |
C00000209
|
| 4967 | OGDH, AKGDH, E1k, OGDC | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (EC:1.2.4.2) |
C00000209
|
| 1555 | CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450 | cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1) |
C00026537
|
| 5562 | PRKAA1, AMPK, AMPKa1 | protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31) |
C00000209
|
| 5563 | PRKAA2, AMPK, AMPK2, AMPKa2, PRKAA | protein kinase, AMP-activated, alpha 2 catalytic subunit (EC:2.7.11.1 2.7.11.27 2.7.11.31) |
C00000209
|
| 6194 | RPS6, S6 | ribosomal protein S6 |
C00000209
|
| 23411 | SIRT1, SIR2L1 | sirtuin 1 |
C00000209
|
| 22933 | SIRT2, SIR2, SIR2L, SIR2L2 | sirtuin 2 (EC:3.5.1.-) |
C00000209
|
| 6720 | SREBF1, SREBP-1c, SREBP1, bHLHd1 | sterol regulatory element binding transcription factor 1 |
C00000209
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00026537
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00026537
|
| 9619 | ABCG1, ABC8, WHITE1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
C00001233
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00001233
|
| 213 | ALB, PRO0883, PRO0903, PRO1341 | albumin |
C00001233
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00001233
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00001233
|
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00001233
|
| 6348 | CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 | chemokine (C-C motif) ligand 3 |
C00001233
|
| 1374 | CPT1A, CPT1, CPT1-L, L-CPT1 | carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21) |
C00001233
|
| 1906 | EDN1, ET1, HDLCQ7, PPET1 | endothelin 1 |
C00001233
|
| 2876 | GPX1, GPXD, GSHPX1 | glutathione peroxidase 1 (EC:1.11.1.9) |
C00001233
|
| 3034 | HAL, HIS, HSTD | histidine ammonia-lyase (EC:4.3.1.3) |
C00001233
|
| 57817 | HAMP, HEPC, HFE2B, LEAP1, PLTR | hepcidin antimicrobial peptide |
C00001233
|
| 3481 | IGF2, C11orf43, IGF-II, PP9974 | insulin-like growth factor 2 (somatomedin A) |
C00001233
|
| 1432 | MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA | mitogen-activated protein kinase 14 (EC:2.7.11.24) |
C00001233
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00026537
|
| 5601 | MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK | mitogen-activated protein kinase 9 (EC:2.7.11.24) |
C00001233
|
| 4493 | MT1E, MT1, MTD | metallothionein 1E |
C00001233
|
| 4494 | MT1F, MT1 | metallothionein 1F |
C00001233
|
| 4496 | MT1H, MT-0, MT-1H, MT-IH, MT1 | metallothionein 1H |
C00001233
|
| 4501 | MT1X, MT-1l, MT1 | metallothionein 1X |
C00001233
|
| 4502 | MT2A, MT2 | metallothionein 2A |
C00001233
|
| 4843 | NOS2, HEP-NOS, INOS, NOS, NOS2A | nitric oxide synthase 2, inducible (EC:1.14.13.39) |
C00001233
|
| 3651 | PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1 | pancreatic and duodenal homeobox 1 |
C00001233
|
| 5465 | PPARA, NR1C1, PPAR, PPARalpha, hPPAR | peroxisome proliferator-activated receptor alpha |
C00001233
|
| 29893 | PSMC3IP, GT198, HOP2, HUMGT198A, ODG3, TBPIP | PSMC3 interacting protein |
C00001233
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00001233
|
| 5054 | SERPINE1, PAI, PAI-1, PAI1, PLANH1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
C00001233
|
| 6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) |
C00001233
|
| 23216 | TBC1D1, TBC, TBC1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
C00001233
|
| 7351 | UCP2, BMIQ4, SLC25A8, UCPH | uncoupling protein 2 (mitochondrial, proton carrier) |
C00001233
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 P47869 |
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #218030 | Apparent mineralocorticoid excess; ame |
P80365
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| #300615 | Brunner syndrome |
P21397
|
| #613630 | Cocoon syndrome |
O15111
|
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #607208 | Dravet syndrome |
P18507
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #607681 | Epilepsy, childhood absence, susceptibility to, 2; eca2 |
P18507
|
| #612269 | Epilepsy, childhood absence, susceptibility to, 5; eca5 |
P28472
|
| #613060 | Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 |
O14764
|
| #611136 | Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 |
P14867
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #604233 | Generalized epilepsy with febrile seizures plus, type 1; gefsp1 |
P18507
|
| #611277 | Generalized epilepsy with febrile seizures plus, type 3; gefsp3 |
P18507
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #137800 | Glioma susceptibility 1; glm1 |
P04626
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #246300 | Leprosy, susceptibility to, 3; lprs3 |
O60603
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #159900 | Myoclonic dystonia |
P14416
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #601665 | Obesity |
P32245
|
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #605361 | Spinocerebellar ataxia 14; sca14 |
P05129
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601367 | Stroke, ischemic |
P00734
P24723 |
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #112100 | Yt blood group antigen |
P22303
|
| KEGG | name | UniProt |
|---|---|---|
| H00783 | Febrile seizures |
O14764
(related)
P18507 (related) |
| H00882 | Cocoon syndrome |
O15111
(related)
|
| H00344 | Leprosy |
O60603
(related)
|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
P11511 (related) |
| H00019 | Pancreatic cancer |
P04626
(related)
|
| H00027 | Ovarian cancer |
P04626
(related)
|
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P35354 (related) |
| H00063 | Spinocerebellar ataxia (SCA) |
P05129
(related)
Q9NUW8 (related) |
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00025 | Penile cancer |
P14780
(related)
P35354 (related) |
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00808 | Idiopathic generalized epilepsies (IGEs) |
P14867
(related)
P18507 (related) |
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
|
| H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
| H00408 | Type I diabetes mellitus |
Q04759
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D007680 | Kidney Neoplasms |
C00000209
C00001513 |
| D007674 | Kidney Diseases |
C00000209
|
| D020520 | Brain Infarction |
C00000209
|
| D002545 | Brain Ischemia |
C00000209
|
| D002653 | Child Behavior Disorders |
C00000209
|
| D002972 | Cleft Palate |
C00000209
|
| D003921 | Diabetes Mellitus, Experimental |
C00000209
|
| D003924 | Diabetes Mellitus, Type 2 |
C00000209
|
| D056486 | Drug-Induced Liver Injury |
C00000209
|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
C00000209
|
| D006330 | Heart Defects, Congenital |
C00000209
|
| D006937 | Hypercholesterolemia |
C00000209
|
| D006943 | Hyperglycemia |
C00000209
|
| D006948 | Hyperkinesis |
C00000209
|
| D006951 | Hyperlipoproteinemias |
C00000209
|
| D006973 | Hypertension |
C00000209
|
| D015228 | Hypertriglyceridemia |
C00000209
|
| D052456 | Hypoalphalipoproteinemias |
C00000209
|
| D007516 | Adenoma, Islet Cell |
C00000209
|
| D019970 | Cocaine-Related Disorders |
C00026537
|
| D017880 | Limb Deformities, Congenital |
C00000209
|
| D009410 | Nerve Degeneration |
C00000209
|
| D019636 | Neurodegenerative Diseases |
C00000209
|
| D010190 | Pancreatic Neoplasms |
C00000209
|
| D010391 | Pemphigoid, Bullous |
C00000209
|
| D012393 | Rosacea |
C00000209
|
| D012640 | Seizures |
C00000209
|
| D020521 | Stroke |
C00000209
|
| D014657 | Vasculitis |
C00000209
|
| D006965 | Hyperplasia |
C00001513
|
| D009362 | Neoplasm Metastasis |
C00001513
|
| D020163 | Ornithine Carbamoyltransferase Deficiency Disease |
C00001513
|
| D010212 | Papilloma |
C00001513
|
| D011230 | Precancerous Conditions |
C00001513
|
| D014516 | Ureteral Neoplasms |
C00001513
|
| D001749 | Urinary Bladder Neoplasms |
C00001513
|
| D003072 | Cognition Disorders |
C00001233
|