Dorstenia turbinata

• Index
• Plant Species
• Metabolite list (8)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Dorstenia turbinata
Genus	Dorstenia
Family	Moraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Dorstenia turbinata
Linked NCBI taxonomy ID	984821
Linked level	species

Family

Family in NCBI taxonomy	Moraceae
ID	3487

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (8)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00007072	Kanzonol C / 2',4',4-Trihydroxy-3'-prenylchalcone	CHEMBL1644933				No. 190	No. 13
C00035164	Turbinatocoumarin					No. 399	No. 25
C00035023	5-Methoxy-3-(3-methyl-2,3-dihydroxybutyl)psoralen / (-)-5-Methoxy-3-(3-methyl-2,3-dihydroxybutyl)-psoralen					No. 579	No. 25
C00029531	Vanillic aldehyde / 4-Hydroxy-3-methoxybenzaldehyde	CHEMBL13883	C100058	18 / 8 / 9	33 / 1	No. 1003
C00002503	Umbelliferon / Umbelliferone / 7-Hydroxycoumarin	CHEMBL51628	C031477	39 / 33 / 32	9 / 0	No. 1030	No. 25
C00000297	Psoralen	CHEMBL164660	D005363	12 / 6 / 6	0 / 5	No. 1282	No. 25
C00019918	Smyrindiol / Smirindiol / (+)-3'-Hydroxymarmesin / (2'S,3'R)-3'-Hydroxymarmesin / (+)-(2S',3'R)-3-Hydroxymarmesin					No. 1336	No. 25
C00035022	4-Methoxyphenol	CHEMBL544		3 / 1 / 0		No. 2352

Human Protein / Gene in interactions

61 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00002503 C00029531 C00035022	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002503 C00029531	2 / 2
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00002503 C00029531	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000297 C00002503	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002503 C00029531	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002503 C00029531	1 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000297 C00002503	3 / 3
P56817	Beta-secretase 1	A1A	C00000297 C00002503	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00000297 C00002503	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002503 C00029531	0 / 0
Q00796	Sorbitol dehydrogenase	Enzyme	C00002503	0 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00002503	1 / 1
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00029531	0 / 0
P51649	Succinate-semialdehyde dehydrogenase, mitochondrial	Oxidoreductase	C00029531	1 / 1
P00918	Carbonic anhydrase 2	Lyase	C00002503	1 / 2
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00029531	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000297	0 / 1
Q9HAW7	UDP-glucuronosyltransferase 1-7	Enzyme	C00029531	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00000297	0 / 0
P04406	Glyceraldehyde-3-phosphate dehydrogenase	Enzyme	C00002503	0 / 0
P28845	Corticosteroid 11-beta-dehydrogenase isozyme 1	Enzyme	C00002503	1 / 1
O43570	Carbonic anhydrase 12	Lyase	C00002503	1 / 2
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00000297	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002503	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002503	0 / 0
O75496	Geminin	Unclassified protein	C00002503	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00029531	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00002503	0 / 0
P18405	3-oxo-5-alpha-steroid 4-dehydrogenase 1	Oxidoreductase	C00002503	0 / 0
P15121	Aldose reductase	Enzyme	C00002503	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00002503	0 / 0
O00519	Fatty-acid amide hydrolase 1	Enzyme	C00029531	0 / 0
P29466	Caspase-1	C14	C00002503	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00002503	4 / 2
P80404	4-aminobutyrate aminotransferase, mitochondrial	Transferase	C00029531	1 / 1
P06280	Alpha-galactosidase A	Enzyme	C00002503	1 / 1
Q96RI1	Bile acid receptor	NR1H4	C00029531	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002503	1 / 1
Q16790	Carbonic anhydrase 9	Lyase	C00002503	0 / 1
P04062	Glucosylceramidase	Enzyme	C00002503	6 / 4
P78527	DNA-dependent protein kinase catalytic subunit	Atypical serine/threonine protein kinase PIKK subfamily	C00029531	0 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00035022	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00002503	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00002503	0 / 3
P22303	Acetylcholinesterase	Hydrolase	C00002503	1 / 0
P20813	Cytochrome P450 2B6	Cytochrome P450 2B6	C00000297	1 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00000297	0 / 0
P55210	Caspase-7	C14	C00002503	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000297	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000297	0 / 1
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00002503	5 / 1
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00029531	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00029531	0 / 0
P10275	Androgen receptor	NR3C4	C00029531	3 / 4
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00002503	1 / 1
Q99700	Ataxin-2	Unclassified protein	C00002503	1 / 1
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00002503	3 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00035022	1 / 0
O00255	Menin	Unclassified protein	C00002503	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002503	1 / 2
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000297	1 / 0

42 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00002503
8574	AKR7A2, AFAR, AFAR1, AFB1-AR1, AKR7	aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (EC:1.1.1.n11)	C00002503
581	BAX, BCL2L4	BCL2-associated X protein	C00002503
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00002503
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00002503
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00002503
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00002503
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00002503
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00002503
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00029531
759	CA1, CA-I, CAB, Car1	carbonic anhydrase I (EC:4.2.1.1)	C00029531
760	CA2, CA-II, CAC, CAII, Car2	carbonic anhydrase II (EC:4.2.1.1)	C00029531
1196	CLK2, hCLK2	CDC-like kinase 2 (EC:2.7.12.1)	C00029531
1490	CTGF, CCN2, HCS24, IGFBP8, NOV2	connective tissue growth factor	C00029531
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00029531
54541	DDIT4, Dig2, REDD-1, REDD1	DNA-damage-inducible transcript 4	C00029531
1789	DNMT3B, ICF, ICF1, M.HsaIIIB	DNA (cytosine-5-)-methyltransferase 3 beta (EC:2.1.1.37)	C00029531
1848	DUSP6, HH19, MKP3, PYST1	dual specificity phosphatase 6 (EC:3.1.3.16 3.1.3.48)	C00029531
2263	FGFR2, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25	fibroblast growth factor receptor 2 (EC:2.7.10.1)	C00029531
2535	FZD2, Fz2, fz-2, fzE2, hFz2	frizzled family receptor 2	C00029531
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00029531
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00029531
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00029531
3251	HPRT1, HGPRT, HPRT	hypoxanthine phosphoribosyltransferase 1 (EC:2.4.2.8)	C00029531
3304	HSPA1B, HSP70-1B, HSP70-2	heat shock 70kDa protein 1B	C00029531
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00029531
3638	INSIG1, CL-6, CL6	insulin induced gene 1	C00029531
3727	JUND, AP-1	jun D proto-oncogene	C00029531
5605	MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2	mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)	C00029531
57787	MARK4, MARK4L, MARK4S, MARKL1, MARKL1L, PAR-1D	MAP/microtubule affinity-regulating kinase 4 (EC:2.7.11.1)	C00029531
4502	MT2A, MT2	metallothionein 2A	C00029531
5514	PPP1R10, CAT53, FB19, PNUTS, PP1R10, R111, p99	protein phosphatase 1, regulatory subunit 10	C00029531
11046	SLC35D2, HFRC1, SQV7L, UGTrel8, hfrc	solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2	C00029531
23657	SLC7A11, CCBR1, xCT	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	C00029531
7041	TGFB1I1, ARA55, HIC-5, HIC5, TSC-5	transforming growth factor beta 1 induced transcript 1	C00029531
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00029531
10626	TRIM16, EBBP	tripartite motif containing 16	C00029531
7360	UGP2, UDPG, UDPGP, UDPGP2, UGP1, UGPP1, UGPP2, pHC379	UDP-glucose pyrophosphorylase 2 (EC:2.7.7.9)	C00029531
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00029531
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00029531
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00029531
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00029531

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions