Species

KNApSAcK Entry

Organism name Phoebe formosana
Genus Phoebe
Family Lauraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Phoebe formosana
Linked NCBI taxonomy ID 128687
Linked level species

Family

Family in NCBI taxonomy Lauraceae
ID 3433

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (10)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00027409 External link 512 Laurotetanin
/ Laurotetanine
/ (+)-Laurotetanine
CHEMBL464098
C008256
No. 20 No. 4
C00027433 External link 512 Laurolitsine
/ (+)-Norboldine
/ (+)-Laurolitsine
CHEMBL487388
C109133
No. 20 No. 4
C00027440 External link 512 Norjuziphine
/ (-)-Norjusiphine
/ (-)-Norjuziphine
CHEMBL462757
No. 253 No. 4
C00025924 External link 512 Juziphine
/ Yuziphine
/ (+)-Juziphine
CHEMBL462956
No. 253 No. 4
C00007211 External link 512 Helioxanthin
CHEMBL436474
No. 285 No. 21
C00027423 External link 512 N-Formylanonaine
/ (-)-N-Formylanonaine
CHEMBL1170090
1 / 4 / 2 No. 553
C00027408 External link 512 Laurodionine
No. 800
C00002683 External link 512 Vanillin
CHEMBL13883
18 / 8 / 9 No. 1003
C00050316 External link 512 (E)-Gadain
CHEMBL395263
CHEMBL459851
7 / 10 / 5 No. 1029 No. 21
C00002657 External link 512 p-Formylphenol
/ 4-Hydroxybenzaldehyde
/ p-Hydroxybenzaldehyde
CHEMBL14193
C011483
3 / 2 / 2 No. 2076

Human Protein / Gene in interactions

26 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P51649 Succinate-semialdehyde dehydrogenase, mitochondrial Oxidoreductase C00002657 C00002683 1 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002683 C00050316 0 / 0
P80404 4-aminobutyrate aminotransferase, mitochondrial Transferase C00002657 C00002683 1 / 1
P14679 Tyrosinase Oxidoreductase C00027423 4 / 2
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00002683 0 / 0
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00002683 0 / 0
Q9HAW7 UDP-glucuronosyltransferase 1-7 Enzyme C00002683 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002683 0 / 0
P14902 Indoleamine 2,3-dioxygenase 1 Enzyme C00002657 0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme C00002683 0 / 0
O00519 Fatty-acid amide hydrolase 1 Enzyme C00002683 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00050316 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00050316 7 / 3
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00002683 0 / 0
P78527 DNA-dependent protein kinase catalytic subunit Atypical serine/threonine protein kinase PIKK subfamily C00002683 0 / 0
Q96RI1 Bile acid receptor NR1H4 C00002683 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002683 2 / 2
Q9Y4X1 UDP-glucuronosyltransferase 2A1 Enzyme C00002683 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00050316 0 / 0
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00002683 0 / 0
Q99700 Ataxin-2 Unclassified protein C00050316 1 / 1
P10275 Androgen receptor NR3C4 C00002683 3 / 4
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00002683 1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00050316 1 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002683 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00050316 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (22)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#119900 Digital clubbing, isolated congenital P15428
#613163 Gaba-transaminase deficiency P80404
#137800 Glioma susceptibility 1; glm1 O75874
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#271980 Succinic semialdehyde dehydrogenase deficiency; ssadhd P51649

KEGG DISEASE (15)

KEGG name UniProt
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00835 Succinic semialdehyde dehydrogenase (SSADH) deficiency P51649 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H01257 GABA-transaminase deficiency P80404 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)