| Organism name | Fernandoa adenophylla |
|---|---|
| Genus | Fernandoa |
| Family | Bignoniaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Fernandoa |
|---|---|
| Linked NCBI taxonomy ID | 260310 |
| Linked level | genus |
| Family in NCBI taxonomy | Bignoniaceae |
|---|---|
| ID | 24079 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00004232
|
Hispidulin 7-glucuronide
/ Hispidulin 7-O-beta-glucuronide / (-)-Hispidulin 7-O-beta-glucuronide |
No. 2 | No. 15 |
|
||||
|
C00004144
|
Apigenin 7-glucuronide
/ Apigenin 7-O-beta-D-glucuronide / (-)-Apigenin 7-O-beta-D-glucuronide |
CHEMBL254213
CHEMBL1980748 |
No. 2 | No. 15 |
|
|||
|
C00004231
|
Hispidulin 7-glucoside
/ Hispidulin 7-O-beta-glucoside / (-)-Hispidulin 7-O-beta-glucoside / Hispidulin-7-O-beta-D-glucopyranoside |
CHEMBL480657
|
No. 2 | No. 15 |
|
|||
|
C00002783
|
Kusaginin
/ Acteoside / Verbascoside |
CHEMBL231853
CHEMBL444478 CHEMBL1364101 |
C058956
|
12 / 1 / 1 | 34 / 3 | No. 33 |
|
|
|
C00030516
|
Isoacteoside
/ Isoverbascoside |
CHEMBL504873
|
C064683
|
6 / 5 / 4 | No. 33 |
|
||
|
C00034597
|
Martynoside
|
CHEMBL234764
CHEMBL503531 CHEMBL2134071 |
1 / 7 / 3 | No. 33 |
|
|||
|
C00036501
|
O-Apiosylverbascoside
/ 2''-O-beta-Apiosylverbascoside |
No. 33 |
|
|||||
|
C00030657
|
Leucosceptoside A
|
CHEMBL450121
|
1 / 0 / 0 | No. 33 |
|
|||
|
C00031274
|
Salidroside
/ Rhodioloside / (-)-Rhodioloside / Tyrosol alpha-(beta-D-glucopyranoside) |
CHEMBL465208
CHEMBL1899113 |
C009172
|
3 / 0 / 0 | No. 45 | No. 72 |
|
|
|
C00036313
|
(+)-Lyoniresinol 3alpha-O-beta-glucopyranoside
/ (+)-Lyoniresinol 3alpha-O-beta-D-glucopyranoside |
CHEMBL464198
CHEMBL1159486 CHEMBL1159487 CHEMBL1813178 CHEMBL1813179 CHEMBL1813180 CHEMBL1813181 CHEMBL2332109 |
6 / 11 / 5 | No. 174 | No. 22 |
|
||
|
C00037137
|
Fernandoside
/ (+)-Fernandoside |
No. 1230 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P17252 | Protein kinase C alpha type | Alpha | C00002783 C00030657 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00002783 C00036313 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00002783 C00031274 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00034597 C00036313 | 7 / 3 |
| O75496 | Geminin | Unclassified protein | C00002783 C00031274 | 0 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00002783 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00036313 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00031274 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00002783 | 0 / 0 |
| P39900 | Macrophage metalloelastase | M10A | C00030516 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00030516 | 0 / 1 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00036313 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00030516 | 2 / 2 |
| Q99700 | Ataxin-2 | Unclassified protein | C00002783 | 1 / 1 |
| Q9P0U3 | Sentrin-specific protease 1 | Enzyme | C00036313 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00036313 | 4 / 2 |
| P45452 | Collagenase 3 | M10A | C00030516 | 1 / 1 |
| P08253 | 72 kDa type IV collagenase | M10A | C00030516 | 1 / 3 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002783 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00002783 | 0 / 0 |
| P08254 | Stromelysin-1 | M10A | C00030516 | 1 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00002783 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00002783 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00002783 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00002783
|
| 405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator |
C00002783
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00002783
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00002783
|
| 894 | CCND2, KIAK0002 | cyclin D2 |
C00002783
|
| 896 | CCND3 | cyclin D3 |
C00002783
|
| 898 | CCNE1, CCNE | cyclin E1 |
C00002783
|
| 1017 | CDK2, p33(CDK2) | cyclin-dependent kinase 2 (EC:2.7.11.22) |
C00002783
|
| 1019 | CDK4, CMM3, PSK-J3 | cyclin-dependent kinase 4 (EC:2.7.11.22) |
C00002783
|
| 1021 | CDK6, PLSTIRE | cyclin-dependent kinase 6 (EC:2.7.11.22) |
C00002783
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00002783
|
| 1027 | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
C00002783
|
| 3627 | CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 | chemokine (C-X-C motif) ligand 10 |
C00002783
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00002783
|
| 1869 | E2F1, E2F-1, RBAP1, RBBP3, RBP3 | E2F transcription factor 1 |
C00002783
|
| 1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00002783
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00002783
|
| 3458 | IFNG, IFG, IFI | interferon, gamma |
C00002783
|
| 3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00002783
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00002783
|
| 3689 | ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
C00002783
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00002783
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00002783
|
| 27035 | NOX1, GP91-2, MOX1, NOH-1, NOH1 | NADPH oxidase 1 |
C00002783
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00002783
|
| 5925 | RB1, OSRC, RB, p105-Rb, pRb, pp110 | retinoblastoma 1 |
C00002783
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002783
|
| 4087 | SMAD2, JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2 | SMAD family member 2 |
C00002783
|
| 4088 | SMAD3, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3 | SMAD family member 3 |
C00002783
|
| 6648 | SOD2, IPOB, MNSOD, MVCD6 | superoxide dismutase 2, mitochondrial (EC:1.15.1.1) |
C00002783
|
| 7039 | TGFA, TFGA | transforming growth factor, alpha |
C00002783
|
| 7040 | TGFB1, CED, DPD1, LAP, TGFB, TGFbeta | transforming growth factor, beta 1 |
C00002783
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00002783
|
| 7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 |
C00002783
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #602111 | Spondyloepimetaphyseal dysplasia, missouri type |
P45452
|
| #601367 | Stroke, ischemic |
P00734
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| KEGG | name | UniProt |
|---|---|---|
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00028 | Choriocarcinoma |
P03956
(related)
P08253 (related) |
| H00025 | Penile cancer |
P08253
(related)
P14780 (related) |
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
P45452 (related) |
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|