Species

KNApSAcK Entry

Organism name Tecomella undulata
Genus Tecomella
Family Bignoniaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Tecomella undulata
Linked NCBI taxonomy ID 680229
Linked level species

Family

Family in NCBI taxonomy Bignoniaceae
ID 24079

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00013595 External link 512 Eupatrin
/ Anisomelin
/ Fastigenin
/ Cirsilineol
/ 5,4'-Dihydroxy-6,7,3'-trimethoxyflavone
CHEMBL487213
C057618
No. 3 No. 15
C00002864 External link 512 Tectoquinone
/ 2-Methylanthraquinone
/ 2-Methylanthracene-9,10-dione
CHEMBL21745
C073955
2 / 2 / 1 No. 41 No. 62
C00029479 External link 512 Veratric acid
/ 3,4-dimethoxybenzoic acid
CHEMBL118903
C009333
10 / 6 / 6 No. 1073
C00037896 External link 512 Tectol
CHEMBL461704
C053744
No. 2127
C00037011 External link 512 Dehydro-alpha-lapachone
CHEMBL272253
C029244
1 / 0 / 0 No. 2274
C00002835 External link 512 Lapachol
CHEMBL15193
C008252
13 / 20 / 50 No. 4183 No. 80
C00010721 External link 512 Undulatin
No. 5630
C00010571 External link 512 Tecoside
No. 6062

Human Protein / Gene in interactions

26 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P04637 Cellular tumor antigen p53 Transcription Factor C00002835 7 / 37
Q16637 Survival motor neuron protein Unclassified protein C00002835 4 / 1
P08246 Neutrophil elastase S1A C00002864 2 / 1
P43166 Carbonic anhydrase 7 Lyase C00029479 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00029479 1 / 2
Q9HC97 G-protein coupled receptor 35 Kynurenic acid receptor C00002835 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00002835 2 / 3
P23280 Carbonic anhydrase 6 Lyase C00029479 0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00029479 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002835 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00029479 1 / 2
P14902 Indoleamine 2,3-dioxygenase 1 Enzyme C00037011 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00029479 2 / 0
P00915 Carbonic anhydrase 1 Lyase C00029479 0 / 0
P08311 Cathepsin G S1A C00002864 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00002835 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00029479 0 / 1
P51580 Thiopurine S-methyltransferase Enzyme C00029479 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002835 0 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00002835 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00002835 4 / 3
Q04760 Lactoylglutathione lyase Enzyme C00002835 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00029479 1 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002835 0 / 0
O00255 Menin Unclassified protein C00002835 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00002835 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (28)

OMIM preferred title UniProt
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#114500 Colorectal cancer; crc P84022
#162800 Cyclic neutropenia P08246
#133239 Esophageal cancer P04637
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#143860 Hyperchlorhidrosis, isolated O43570
#145000 Hyperparathyroidism 1; hrpt1 O00255
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#211980 Lung cancer P04637
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#600852 Retinitis pigmentosa 17; rp17 P22748
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#610460 Thiopurine s-methyltransferase deficiency P51580
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (56)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00100 Neutropenic disorders P08246 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H00964 Thiopurine S-methyltransferase deficiency (TPMT deficiency) P51580 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)