| Organism name | Pinus taeda |
|---|---|
| Genus | Pinus |
| Family | Pinaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Pinus taeda |
|---|---|
| Linked NCBI taxonomy ID | 3352 |
| Linked level | species |
| Family in NCBI taxonomy | Pinaceae |
|---|---|
| ID | 3318 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | Spermatophyta |
|---|---|
| ID | 58024 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00009076
|
Procyanidin B5
/ Epicatechin-(4beta-6)-epicatechin |
CHEMBL506487
CHEMBL502984 CHEMBL451115 |
No. 16 | No. 19 |
|
|||
|
C00009074
|
Procyanidin B7
/ Catechin-(4beta->6)-catechin |
CHEMBL506487
CHEMBL502984 CHEMBL451115 |
No. 16 | No. 19 |
|
|||
|
C00009089
|
Arecatannin B1
|
CHEMBL592329
|
2 / 3 / 4 | No. 29 | No. 19 |
|
||
|
C00009097
|
Arecatamnin A1
/ [Epicatechin-(4beta->8)]2-catechin |
CHEMBL290632
|
13 / 5 / 6 | No. 29 | No. 19 |
|
||
|
C00009098
|
Procyanidin C1
/ [Epicatechin-(4beta->8)]2-epicatechin |
CHEMBL290632
|
13 / 5 / 6 | No. 29 | No. 19 |
|
||
|
C00009086
|
Epicatechin-(4beta->6)-epicatechin-(4beta->8)-catechin
|
CHEMBL592228
|
2 / 3 / 4 | No. 29 | No. 19 |
|
||
|
C00023770
|
Sitosterol
/ Stigmasta-5,22-dien-3beta-ol / (24R)24-Ethylcholesta-5,22-dien-3beta-ol |
CHEMBL221542
CHEMBL1398443 CHEMBL1875388 |
17 / 19 / 12 | No. 53 | No. 11 |
|
||
|
C00003444
|
miropinic acid
/ Isopimaric acid / isodextropimaric acid |
CHEMBL512164
|
C115138
|
3 / 1 / 1 | No. 208 | No. 48 |
|
|
|
C00002897
|
Pinosylvin
/ Pinosylvine / 3,5-Dihydroxystilbene |
CHEMBL101506
CHEMBL2203685 |
1 / 0 / 1 | No. 295 | No. 13 |
|
||
|
C00002898
|
Pinosylvin methyl ether
/ 3-Hydroxy-5-methoxystilbene |
CHEMBL186366
|
18 / 39 / 57 | No. 295 | No. 13 |
|
||
|
C00042455
|
Dehydroabietic acid
|
CHEMBL12850
|
C013913
|
No. 323 | No. 41 |
|
||
|
C00015883
|
Stilbene
|
CHEMBL113028
CHEMBL393702 |
2 / 2 / 2 | No. 3909 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P08253 | 72 kDa type IV collagenase | M10A | C00009086 C00009089 C00009097 C00009098 | 1 / 3 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00009086 C00009089 C00009097 C00009098 | 2 / 2 |
| P41743 | Protein kinase C iota type | Iota | C00009097 C00009098 | 0 / 0 |
| P24723 | Protein kinase C eta type | Eta | C00009097 C00009098 | 1 / 0 |
| P05771 | Protein kinase C beta type | Alpha | C00009097 C00009098 | 0 / 0 |
| P05129 | Protein kinase C gamma type | Alpha | C00009097 C00009098 | 1 / 1 |
| Q05655 | Protein kinase C delta type | Delta | C00009097 C00009098 | 0 / 0 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00015883 C00023770 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00009097 C00009098 | 0 / 0 |
| O94806 | Serine/threonine-protein kinase D3 | Pkd | C00009097 C00009098 | 0 / 0 |
| Q02156 | Protein kinase C epsilon type | Eta | C00009097 C00009098 | 0 / 0 |
| Q04759 | Protein kinase C theta type | Delta | C00009097 C00009098 | 0 / 1 |
| Q05513 | Protein kinase C zeta type | Iota | C00009097 C00009098 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002898 C00023770 | 0 / 1 |
| Q15139 | Serine/threonine-protein kinase D1 | Pkd | C00009097 C00009098 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00023770 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002898 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00003444 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00002898 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00002898 | 4 / 2 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00023770 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00002898 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00002898 | 7 / 3 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00002898 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00023770 | 4 / 2 |
| P14679 | Tyrosinase | Oxidoreductase | C00023770 | 4 / 2 |
| P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | GABA-A alpha | C00003444 | 1 / 1 |
| P47870 | Gamma-aminobutyric acid receptor subunit beta-2 | GABA-A beta | C00003444 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002898 | 3 / 3 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002898 | 2 / 2 |
| P03372 | Estrogen receptor | NR3A1 | C00023770 | 1 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00023770 | 1 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00023770 | 0 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00002898 | 4 / 3 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00002897 | 0 / 1 |
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00023770 | 1 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002898 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00023770 | 1 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002898 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00002898 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002898 | 1 / 2 |
| P08183 | Multidrug resistance protein 1 | drug | C00023770 | 1 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00023770 | 3 / 2 |
| P37840 | Alpha-synuclein | Unclassified protein | C00002898 | 4 / 2 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00023770 | 0 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00002898 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00023770 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00015883 | 2 / 2 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00023770 | 2 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00002898 | 4 / 1 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002898 | 7 / 37 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00023770 | 1 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #218030 | Apparent mineralocorticoid excess; ame |
P80365
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #611136 | Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 |
P14867
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P04637
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #167000 | Ovarian cancer |
P38398
|
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #605361 | Spinocerebellar ataxia 14; sca14 |
P05129
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601367 | Stroke, ischemic |
P00734
P24723 |
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P08253 (related) P14780 (related) |
| H00027 | Ovarian cancer |
P04637
(related)
P38398 (related) |
| H00028 | Choriocarcinoma |
P04637
(related)
P08253 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
P38398 (related) |
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
P14679 (marker) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00063 | Spinocerebellar ataxia (SCA) |
P05129
(related)
Q9NUW8 (related) |
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00808 | Idiopathic generalized epilepsies (IGEs) |
P14867
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00408 | Type I diabetes mellitus |
Q04759
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|