Murraya paniculata
Species
KNApSAcK Entry
| Organism name | Murraya paniculata |
|---|---|
| Genus | Murraya |
| Family | Rutaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Murraya paniculata |
|---|---|
| Linked NCBI taxonomy ID | 43711 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Rutaceae |
|---|---|
| ID | 23513 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (35)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00013340
|
5,3',5'-Trihydroxy-6,7,4'-trimethoxyflavone
/ 2-(3,5-Dihydroxy-4-methoxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-1-benzopyran-4-one |
No. 3 | No. 15 |
|
||||
|
C00003918
|
5,7,3',4',5'-Pentamethoxyflavone
/ Tricetin 5,7,3',4',5'-pentamethyl ether / 5,7-Dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL2074901
|
1 / 1 / 0 | No. 8 | No. 15 |
|
||
|
C00003936
|
Demethylnobiletin
/ 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxy-4H-1-benzopyran-4-one |
CHEMBL75978
|
21 / 22 / 16 | No. 8 | No. 15 |
|
||
|
C00003947
|
5,3'-Dihydroxy-6,7,4',5'-tetramethoxyflavone
/ 5-Hydroxy-2-(3-hydroxy-4,5-dimethoxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one |
No. 8 | No. 15 |
|
||||
|
C00003949
|
Umuhengerin
/ 5-Hydroxy-6,7,3',4',5'-pentamethoxyflavone / 5-Hydroxy-6,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL485823
|
C057913
|
No. 8 | No. 15 |
|
||
|
C00003962
|
Bannamurpanisin
|
No. 8 | No. 15 |
|
||||
|
C00003970
|
Gardenin E
/ 3',5,5'-Trihydroxy-4',6,7,8-tetramethoxyflavone / 2-(3,5-Dihydroxy-4-methoxyphenyl)-5-hydroxy-6,7,8-trimethoxy-4H-1-benzopyran-4-one |
No. 8 | No. 15 |
|
||||
|
C00003972
|
Gardenin C
/ 3',5-Dihydroxy-4',5',6,7,8-pentamethoxyflavon / 5-Hydroxy-2-(3-hydroxy-4,5-dimethoxyphenyl)-6,7,8-trimethoxy-4H-1-benzopyran-4-one |
No. 8 | No. 15 |
|
||||
|
C00003976
|
Gardenin A
/ 5-Hydroxy-3',4',5',6,7,8-hexamethoxyflavone / 5-Hydroxy-6,7,8-trimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL77705
|
21 / 18 / 8 | No. 8 | No. 15 |
|
||
|
C00004082
|
5,6,7,3',4',5'-Hexamethoxyflavone
/ 5,6,7-Trimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL370963
|
1 / 1 / 0 | No. 8 | No. 15 |
|
||
|
C00004744
|
Gossypetin 3,7,8,3',4'-pentamethyl ether
/ 5-Hydroxy-3,7,8,3',4'-pentamethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,7,8-trimethoxy-4H-1-benzopyran-4-one |
CHEMBL479326
|
No. 8 | No. 15 |
|
|||
|
C00013381
|
8-Hydroxy-3,5,7,3',4',5'-hexamethoxyflavone
/ 8-Hydroxy-3,5,7-trimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one |
No. 8 | No. 15 |
|
||||
|
C00004778
|
Hexamethylmyricetin
/ Hexa-O-methylmyricitin / Myricetin hexamethyl ether / 3,5,7,3',4',5'-Hexamethoxyflavone / 3,5,7-Trimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL357089
|
1 / 0 / 0 | No. 8 | No. 15 |
|
||
|
C00004835
|
4'-Hydroxy-3,5,6,7,3',5'-hexamethoxyflavone
|
No. 8 | No. 15 |
|
||||
|
C00004836
|
5-Hydroxy-3,6,7,3',4',5'-hexamethoxyflavone
/ 5-Hydroxy-3,6,7-trimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-Benzopyran-4-one |
No. 8 | No. 15 |
|
||||
|
C00004837
|
3,5,6,7,3',4',5'-Heptamethoxyflavone
/ 3,5,6,7-Tetramethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one |
No. 8 | No. 15 |
|
||||
|
C00004847
|
Hibiscetin heptamethyl ether
|
No. 8 | No. 15 |
|
||||
|
C00013382
|
5-Hydroxy-3,3',4',5',7,8-hexamethoxyflavone
/ 5-Hydroxy-3,7,8-trimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one |
No. 8 | No. 15 |
|
||||
|
C00013373
|
3-Hydroxy-5,7,3',4',5'-pentamethoxyflavone
/ 3-Hydroxy-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one |
No. 8 | No. 15 |
|
||||
|
C00004745
|
Gossypetin hexamethyl ether
/ 3,5,7,8,3',4'-Hexamethoxyflavone / 2-(3,4-Dimethoxyphenyl)-3,5,7,8-tetramethoxy-4H-1-benzopyran-4-one |
No. 8 | No. 15 |
|
||||
|
C00019970
|
Murrayacarpin B
|
No. 364 | No. 25 |
|
||||
|
C00019812
|
Chloculol
|
No. 1039 |
|
|||||
|
C00019966
|
Murracarpin
|
No. 1039 |
|
|||||
|
C00037493
|
Meranzin hydrate
/ (-)-Meranzin hydrate |
CHEMBL433093
|
2 / 0 / 0 | No. 1726 |
|
|||
|
C00019969
|
Murrayacarpin A
|
No. 1814 |
|
|||||
|
C00019968
|
Murralonginol isovalerate
|
No. 1945 |
|
|||||
|
C00019994
|
Paniculonol isovalerate
|
No. 1945 |
|
|||||
|
C00019936
|
Isomurralonginol isovalerate
|
No. 1945 |
|
|||||
|
C00026590
|
Paniculidine C
|
No. 2298 |
|
|||||
|
C00026589
|
Paniculidine B
|
No. 2298 |
|
|||||
|
C00019967
|
Murraculatin
|
No. 3868 |
|
|||||
|
C00019987
|
Omphalocarpin
|
No. 3868 |
|
|||||
|
C00019974
|
Murrayanone
|
No. 4290 |
|
|||||
|
C00000490
|
Yuehchukene
|
C047409
|
No. 5887 |
|
||||
|
C00029074
|
Tamynine
|
No. 7142 |
|
Human Protein / Gene in interactions
29 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q9BVA1 | Tubulin beta-2B chain | Structural | C00003936 C00003976 | 1 / 0 |
| Q9BUF5 | Tubulin beta-6 chain | Structural | C00003936 C00003976 | 0 / 0 |
| Q9BQE3 | Tubulin alpha-1C chain | Unclassified protein | C00003936 C00003976 | 0 / 0 |
| Q6PEY2 | Tubulin alpha-3E chain | Unclassified protein | C00003936 C00003976 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00003918 C00004082 | 1 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003936 C00003976 | 0 / 0 |
| Q13885 | Tubulin beta-2A chain | Structural | C00003936 C00003976 | 0 / 0 |
| P68363 | Tubulin alpha-1B chain | Unclassified protein | C00003936 C00003976 | 0 / 0 |
| Q13509 | Tubulin beta-3 chain | Structural | C00003936 C00003976 | 2 / 1 |
| P68371 | Tubulin beta-4B chain | Structural | C00003936 C00003976 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003936 C00003976 | 0 / 1 |
| Q71U36 | Tubulin alpha-1A chain | Structural | C00003936 C00003976 | 1 / 1 |
| P07437 | Tubulin beta chain | Structural | C00003936 C00003976 | 0 / 0 |
| Q3ZCM7 | Tubulin beta-8 chain | Structural | C00003936 C00003976 | 0 / 0 |
| P04350 | Tubulin beta-4A chain | Structural | C00003936 C00003976 | 2 / 0 |
| P68366 | Tubulin alpha-4A chain | Structural | C00003936 C00003976 | 0 / 0 |
| Q9H4B7 | Tubulin beta-1 chain | Structural | C00003936 C00003976 | 1 / 0 |
| Q13748 | Tubulin alpha-3C/D chain | Structural | C00003936 C00003976 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00037493 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003976 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00003936 | 4 / 3 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00003976 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00003936 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00037493 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00003976 | 7 / 3 |
| P37840 | Alpha-synuclein | Unclassified protein | C00003976 | 4 / 2 |
| P02545 | Prelamin-A/C | Unclassified protein | C00003936 | 11 / 10 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00003936 | 0 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00004778 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (34)
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #614039 | Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 |
Q13509
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #128101 | Dystonia 4, torsion, autosomal dominant; dyt4 |
P04350
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #600638 | Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a |
Q13509
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #612438 | Leukodystrophy, hypomyelinating, 6; hld6 |
P04350
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #611603 | Lissencephaly 3; lis3 |
Q71U36
|
| #613112 | Macrothrombocytopenia, autosomal dominant, tubb1-related |
Q9H4B7
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #610031 | Polymicrogyria, symmetric or asymmetric; pmgysa |
Q9BVA1
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
KEGG DISEASE (21)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00838 | Congenital fibrosis of the extraocular muscles (CFEOM) |
Q13509
(related)
|
| H00268 | Lissencephaly (LIS) |
Q71U36
(related)
|