GenomeNet

Database: Pfam
Entry: PH_8
LinkDB: PH_8
Original site: PH_8 
#=GF ID   PH_8
#=GF AC   PF15409.6
#=GF DE   Pleckstrin homology domain
#=GF AU   Wood V;0000-0001-6330-7526
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Jackhmmer:O13944
#=GF GA   30.00 30.00;
#=GF TC   30.00 30.00;
#=GF NC   29.90 29.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Pleckstrin_homology_domain
#=GF RN   [1]
#=GF RM   7985225
#=GF RT   PH domain: the first anniversary. 
#=GF RA   Gibson TJ, Hyvonen M, Musacchio A, Saraste M, Birney E; 
#=GF RL   Trends Biochem Sci 1994;19:349-353.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This Pleckstrin homology domain is found in some fungal species.
#=GF SQ   1163
#=GS W5N787_LEPOC/76-165         AC W5N787.1
#=GS A0A1V4JQT8_PATFA/57-146     AC A0A1V4JQT8.1
#=GS A0A2K5HMM8_COLAP/70-159     AC A0A2K5HMM8.1
#=GS A0A0V0S3L1_9BILA/213-301    AC A0A0V0S3L1.1
#=GS A0A151P5M2_ALLMI/59-148     AC A0A151P5M2.1
#=GS G7E574_MIXOS/12-97          AC G7E574.1
#=GS H2TAY0_TAKRU/27-109         AC H2TAY0.1
#=GS A0A226MKM8_CALSU/70-159     AC A0A226MKM8.1
#=GS A0A139WE79_TRICA/113-202    AC A0A139WE79.1
#=GS A0A1W5CRW4_9LECA/653-741    AC A0A1W5CRW4.1
#=GS A0A1L8FW03_XENLA/119-208    AC A0A1L8FW03.1
#=GS A0A0D1Z588_9EURO/225-313    AC A0A0D1Z588.1
#=GS A0A2K5M3I0_CERAT/52-141     AC A0A2K5M3I0.1
#=GS A0A286X8R1_CAVPO/91-180     AC A0A286X8R1.1
#=GS F6TXN7_HORSE/79-170         AC F6TXN7.1
#=GS A0A2I4C4H6_9TELE/78-167     AC A0A2I4C4H6.1
#=GS A0A151MQK0_ALLMI/55-144     AC A0A151MQK0.1
#=GS A0A2I2U6Z4_FELCA/91-180     AC A0A2I2U6Z4.1
#=GS A0A099ZN96_TINGU/26-115     AC A0A099ZN96.1
#=GS A0A284RB33_9AGAR/34-120     AC A0A284RB33.1
#=GS A0A1D5R8B0_MACMU/91-180     AC A0A1D5R8B0.1
#=GS L8X2J1_THACA/460-544        AC L8X2J1.1
#=GS A0A2D0PWR7_ICTPU/61-150     AC A0A2D0PWR7.1
#=GS A0A287D5A5_ICTTR/91-180     AC A0A287D5A5.1
#=GS G1T287_RABIT/75-166         AC G1T287.1
#=GS A0A2K5MY11_CERAT/79-170     AC A0A2K5MY11.1
#=GS A0A1S3R879_SALSA/79-168     AC A0A1S3R879.1
#=GS A0A2K5IAZ4_COLAP/56-145     AC A0A2K5IAZ4.1
#=GS U7PLX6_SPOS1/273-361        AC U7PLX6.1
#=GS A0A0C3HEH8_9PEZI/224-312    AC A0A0C3HEH8.1
#=GS A0A2K5HMK4_COLAP/91-180     AC A0A2K5HMK4.1
#=GS E9ESZ7_METRA/218-306        AC E9ESZ7.1
#=GS R4XF63_TAPDE/93-181         AC R4XF63.1
#=GS A0A2I3HB68_NOMLE/91-180     AC A0A2I3HB68.1
#=GS M4ASR9_XIPMA/71-160         AC M4ASR9.1
#=GS H1VVI1_COLHI/216-304        AC H1VVI1.1
#=GS A0A1B8GJ43_9PEZI/229-317    AC A0A1B8GJ43.1
#=GS G3P0F6_GASAC/91-180         AC G3P0F6.1
#=GS M2YZV4_PSEFD/210-298        AC M2YZV4.1
#=GS A0A2D0PWP7_ICTPU/62-151     AC A0A2D0PWP7.1
#=GS A0A0H5C476_CYBJA/173-261    AC A0A0H5C476.1
#=GS W6YPV7_COCCA/221-309        AC W6YPV7.1
#=GS A0A2H3J125_WOLCO/25-110     AC A0A2H3J125.1
#=GS A0A2D0PYF5_ICTPU/62-151     AC A0A2D0PYF5.1
#=GS E7KPC9_YEASL/226-313        AC E7KPC9.1
#=GS H2V672_TAKRU/1-88           AC H2V672.1
#=GS I3L7E7_PIG/91-180           AC I3L7E7.2
#=GS A0A1S3S6H5_SALSA/80-169     AC A0A1S3S6H5.1
#=GS A0A094J637_9PEZI/229-317    AC A0A094J637.1
#=GS G9MJ47_HYPVG/216-304        AC G9MJ47.1
#=GS A0A0G2DS64_9PEZI/232-320    AC A0A0G2DS64.1
#=GS N1PVJ5_DOTSN/237-325        AC N1PVJ5.1
#=GS A0A1D5Q6X0_MACMU/91-180     AC A0A1D5Q6X0.1
#=GS A0A194QCA1_PAPXU/101-186    AC A0A194QCA1.1
#=GS A0A2I3LIP0_PAPAN/56-145     AC A0A2I3LIP0.1
#=GS I1CQC2_RHIO9/1-77           AC I1CQC2.1
#=GS A0A0F0ILU6_ASPPU/1521-1609  AC A0A0F0ILU6.1
#=GS S7MNJ4_MYOBR/52-141         AC S7MNJ4.1
#=GS F0XGR0_GROCL/1111-1199      AC F0XGR0.1
#=GS F1ST95_PIG/56-145           AC F1ST95.3
#=GS M7PGY1_PNEMU/174-262        AC M7PGY1.1
#=GS D3YTT6_MOUSE/55-144         AC D3YTT6.1
#=GS A0A2I3RFA8_PANTR/79-170     AC A0A2I3RFA8.1
#=GS A0A0C9Y2G0_9AGAR/6-92       AC A0A0C9Y2G0.1
#=GS H2V670_TAKRU/59-148         AC H2V670.1
#=GS A0A1U7SAF3_ALLSI/55-144     AC A0A1U7SAF3.1
#=GS A0A2K5NDB6_CERAT/91-180     AC A0A2K5NDB6.1
#=GS H0VQR5_CAVPO/37-121         AC H0VQR5.2
#=GS OSH3_YEAST/226-313          AC P38713.1
#=GS OSH3_YEAST/226-313          DR PDB; 4IAP B; 1237-1313;
#=GS OSH3_YEAST/226-313          DR PDB; 4IAP A; 1237-1313;
#=GS A0A093J918_DRYPU/26-115     AC A0A093J918.1
#=GS A0A177ULZ6_9BASI/28-113     AC A0A177ULZ6.1
#=GS A0A1I8I763_9PLAT/101-191    AC A0A1I8I763.1
#=GS A0A179G9W1_9HYPO/214-302    AC A0A179G9W1.1
#=GS G3NW29_GASAC/45-134         AC G3NW29.1
#=GS H2V668_TAKRU/92-181         AC H2V668.1
#=GS A0A2H3C1R3_9AGAR/34-120     AC A0A2H3C1R3.1
#=GS G3W0Y3_SARHA/91-180         AC G3W0Y3.1
#=GS W9YU07_9EURO/226-314        AC W9YU07.1
#=GS A0A0D1XFI6_9PEZI/228-315    AC A0A0D1XFI6.1
#=GS A0A2K5IB93_COLAP/56-145     AC A0A2K5IB93.1
#=GS A0A0D9RP18_CHLSB/91-180     AC A0A0D9RP18.1
#=GS A0A1S3EJW8_DIPOR/52-141     AC A0A1S3EJW8.1
#=GS A0A068SD99_9FUNG/219-305    AC A0A068SD99.1
#=GS A0A1I8IFV8_9PLAT/101-191    AC A0A1I8IFV8.1
#=GS A0A286XTS7_CAVPO/47-136     AC A0A286XTS7.1
#=GS C4JWI3_UNCRE/190-278        AC C4JWI3.1
#=GS H2PMM2_PONAB/56-145         AC H2PMM2.1
#=GS A0A0B7MXF7_9FUNG/195-281    AC A0A0B7MXF7.1
#=GS A0A058Z4E0_9EUKA/200-287    AC A0A058Z4E0.1
#=GS A0A1C1CG82_9EURO/227-315    AC A0A1C1CG82.1
#=GS A0A0P7BTP2_9HYPO/240-328    AC A0A0P7BTP2.1
#=GS A0A0D2AV39_9EURO/222-310    AC A0A0D2AV39.1
#=GS A0A2I3GD33_NOMLE/56-145     AC A0A2I3GD33.1
#=GS A0A0D7A3S1_9AGAR/21-107     AC A0A0D7A3S1.1
#=GS A0A2I0LSD3_COLLI/57-146     AC A0A2I0LSD3.1
#=GS S7NDG0_MYOBR/37-119         AC S7NDG0.1
#=GS A0A068S870_9FUNG/186-272    AC A0A068S870.1
#=GS A0A093I805_STRCA/1-77       AC A0A093I805.1
#=GS A0A063C1E0_9HYPO/214-302    AC A0A063C1E0.1
#=GS H3DHU0_TETNG/96-185         AC H3DHU0.1
#=GS S9XI66_CAMFR/20-101         AC S9XI66.1
#=GS F7CCK9_MACMU/56-145         AC F7CCK9.2
#=GS A0A093ITW6_FULGA/97-186     AC A0A093ITW6.1
#=GS H2U4M5_TAKRU/1-88           AC H2U4M5.1
#=GS A0A0N0RTX9_9HYPO/218-306    AC A0A0N0RTX9.1
#=GS A0A093LVM1_EURHL/1-77       AC A0A093LVM1.1
#=GS A0A0L6V9V5_9BASI/20-108     AC A0A0L6V9V5.1
#=GS A0A1V4KBV0_PATFA/55-144     AC A0A1V4KBV0.1
#=GS OSBL3_HUMAN/56-145          AC Q9H4L5.1
#=GS A0A1S3A471_ERIEU/56-145     AC A0A1S3A471.1
#=GS L0PGF2_PNEJ8/176-263        AC L0PGF2.1
#=GS I2JW32_DEKBR/1-47           AC I2JW32.1
#=GS A0A0G4LWV0_9PEZI/221-309    AC A0A0G4LWV0.1
#=GS G1KND1_ANOCA/55-144         AC G1KND1.2
#=GS A0A091DX87_FUKDA/82-171     AC A0A091DX87.1
#=GS K5XD34_PHACS/15-100         AC K5XD34.1
#=GS C4R4I4_KOMPG/250-339        AC C4R4I4.1
#=GS G7PU60_MACFA/52-141         AC G7PU60.1
#=GS A0A074Y4C7_9PEZI/220-308    AC A0A074Y4C7.1
#=GS A0A017SHN1_9EURO/205-293    AC A0A017SHN1.1
#=GS W2QIH1_PHYPN/56-149         AC W2QIH1.1
#=GS X0C8Z0_FUSOX/97-185         AC X0C8Z0.1
#=GS A0A1S3NGT3_SALSA/82-171     AC A0A1S3NGT3.1
#=GS A0A2I3MUD1_PAPAN/91-180     AC A0A2I3MUD1.1
#=GS M3YPR5_MUSPF/56-145         AC M3YPR5.1
#=GS A0A1Z5TEA2_HORWE/371-459    AC A0A1Z5TEA2.1
#=GS A0A1L9VJN4_ASPGL/205-293    AC A0A1L9VJN4.1
#=GS E2QYC7_CANLF/81-170         AC E2QYC7.2
#=GS A0A166JC01_9HOMO/52-138     AC A0A166JC01.1
#=GS H2U4L7_TAKRU/84-166         AC H2U4L7.1
#=GS A0A084QL53_STAC4/220-308    AC A0A084QL53.1
#=GS A5DMQ9_PICGU/208-295        AC A5DMQ9.2
#=GS G3UK60_LOXAF/118-207        AC G3UK60.1
#=GS A0A1E5R8X5_9ASCO/265-354    AC A0A1E5R8X5.1
#=GS A0A0C3S7U0_PHLGI/35-121     AC A0A0C3S7U0.1
#=GS A0A2K5M3K2_CERAT/52-141     AC A0A2K5M3K2.1
#=GS A0A1A0HIR7_9ASCO/212-299    AC A0A1A0HIR7.1
#=GS A0A0L0RXD8_ALLMA/204-289    AC A0A0L0RXD8.1
#=GS I3MLD3_ICTTR/32-123         AC I3MLD3.2
#=GS A0A087RK15_APTFO/1-77       AC A0A087RK15.1
#=GS A0A0V0V706_9BILA/395-483    AC A0A0V0V706.1
#=GS A0A2C5X4A6_9PEZI/244-332    AC A0A2C5X4A6.1
#=GS A0A0H2RQ29_9HOMO/36-122     AC A0A0H2RQ29.1
#=GS H2TAY2_TAKRU/1-88           AC H2TAY2.1
#=GS F0UAH7_AJEC8/220-308        AC F0UAH7.1
#=GS A0A1U7S7U8_ALLSI/55-144     AC A0A1U7S7U8.1
#=GS A0A0P7WSF7_9TELE/47-136     AC A0A0P7WSF7.1
#=GS E1BBD8_BOVIN/52-141         AC E1BBD8.1
#=GS E6ZTG4_SPORE/32-117         AC E6ZTG4.1
#=GS A0A165EDF9_9APHY/29-115     AC A0A165EDF9.1
#=GS A0A0T6B1Z8_9SCAR/94-183     AC A0A0T6B1Z8.1
#=GS V5HS10_BYSSN/215-303        AC V5HS10.1
#=GS A0A2I4BG04_9TELE/45-134     AC A0A2I4BG04.1
#=GS A0A091KY27_9GRUI/58-147     AC A0A091KY27.1
#=GS A0A094K6E4_ANTCR/27-116     AC A0A094K6E4.1
#=GS A0A1V6ST48_9EURO/201-289    AC A0A1V6ST48.1
#=GS A0A287AQ16_PIG/91-180       AC A0A287AQ16.1
#=GS A0A091QL73_9GRUI/26-115     AC A0A091QL73.1
#=GS G3QYZ4_GORGO/70-159         AC G3QYZ4.2
#=GS J3QLK7_HUMAN/52-141         AC J3QLK7.1
#=GS G7XFF4_ASPKW/205-293        AC G7XFF4.1
#=GS F7IH05_CALJA/91-180         AC F7IH05.1
#=GS A0A238FI54_9BASI/19-88      AC A0A238FI54.1
#=GS H2VB97_TAKRU/47-136         AC H2VB97.1
#=GS A0A1S2ZBP1_ERIEU/78-169     AC A0A1S2ZBP1.1
#=GS A0A1Y2HDV3_9FUNG/221-306    AC A0A1Y2HDV3.1
#=GS A0A163JD89_ABSGL/146-234    AC A0A163JD89.1
#=GS H2TAY3_TAKRU/6-95           AC H2TAY3.1
#=GS A0A1D5P5J6_CHICK/93-182     AC A0A1D5P5J6.1
#=GS F8WIZ7_MOUSE/91-180         AC F8WIZ7.1
#=GS A0A0C9MC09_9FUNG/178-264    AC A0A0C9MC09.1
#=GS A0A0D2XN03_FUSO4/215-303    AC A0A0D2XN03.1
#=GS A0A1R1Y519_9FUNG/223-308    AC A0A1R1Y519.1
#=GS A0A137P3U4_CONC2/205-289    AC A0A137P3U4.1
#=GS A0A1V9XNT1_9ACAR/28-118     AC A0A1V9XNT1.1
#=GS A0A1S3M592_SALSA/46-143     AC A0A1S3M592.1
#=GS A0A096M709_POEFO/70-159     AC A0A096M709.1
#=GS A0A0F7TLT5_9EURO/273-361    AC A0A0F7TLT5.1
#=GS H0V951_CAVPO/55-144         AC H0V951.2
#=GS A0A093QUY9_PHACA/26-115     AC A0A093QUY9.1
#=GS H2PB97_PONAB/79-170         AC H2PB97.1
#=GS A0A1S3Q3R2_SALSA/79-168     AC A0A1S3Q3R2.1
#=GS I3KPA4_ORENI/77-166         AC I3KPA4.1
#=GS A0A096P3Z8_PAPAN/52-141     AC A0A096P3Z8.1
#=GS A0A1A6H1R6_NEOLE/12-101     AC A0A1A6H1R6.1
#=GS G8ZV71_TORDC/227-315        AC G8ZV71.1
#=GS U3JB03_DANRE/1-68           AC U3JB03.6
#=GS A0A2I3N8A0_PAPAN/52-141     AC A0A2I3N8A0.1
#=GS G7PKX7_MACFA/91-180         AC G7PKX7.1
#=GS A0A1S3AFS4_ERIEU/91-180     AC A0A1S3AFS4.1
#=GS A0A286X7Z9_CAVPO/55-144     AC A0A286X7Z9.1
#=GS A0A091LNU6_CATAU/98-187     AC A0A091LNU6.1
#=GS A0A1E4SI37_9ASCO/270-359    AC A0A1E4SI37.1
#=GS H2LUG4_ORYLA/56-145         AC H2LUG4.1
#=GS S8EIQ6_FOMPI/8-94           AC S8EIQ6.1
#=GS A0A162P5C9_9PEZI/250-338    AC A0A162P5C9.1
#=GS A0A0B7N1W3_9FUNG/153-239    AC A0A0B7N1W3.1
#=GS A0A0N4WAF2_HAEPC/1-80       AC A0A0N4WAF2.1
#=GS R1GIE6_BOTPV/231-319        AC R1GIE6.1
#=GS A0A0D2FN23_9EURO/226-314    AC A0A0D2FN23.1
#=GS B6JVE7_SCHJY/144-232        AC B6JVE7.1
#=GS A0A2H3SRE0_FUSOX/215-303    AC A0A2H3SRE0.1
#=GS A0A0A0A2E4_CHAVO/59-148     AC A0A0A0A2E4.1
#=GS A0A093IQ81_EURHL/26-115     AC A0A093IQ81.1
#=GS X0CHZ2_FUSOX/219-307        AC X0CHZ2.1
#=GS A0A0G2HV77_9EURO/220-308    AC A0A0G2HV77.1
#=GS H2YR81_CIOSA/13-102         AC H2YR81.1
#=GS A0A0A0A457_CHAVO/26-115     AC A0A0A0A457.1
#=GS U3ISG0_ANAPL/1-78           AC U3ISG0.1
#=GS A0A0L0S285_ALLMA/205-290    AC A0A0L0S285.1
#=GS A0A1D5P2S4_CHICK/57-146     AC A0A1D5P2S4.1
#=GS Q4WWH5_ASPFU/199-287        AC Q4WWH5.2
#=GS A0A091UBB3_PHORB/26-115     AC A0A091UBB3.1
#=GS A8PWI5_MALGO/12-97          AC A8PWI5.1
#=GS A0A194QTJ1_PAPMA/95-180     AC A0A194QTJ1.1
#=GS A0A096P033_PAPAN/91-180     AC A0A096P033.2
#=GS A0A178E8N1_9PLEO/221-309    AC A0A178E8N1.1
#=GS A0A0U5G3L9_9EURO/205-293    AC A0A0U5G3L9.1
#=GS A0A287D186_ICTTR/91-180     AC A0A287D186.1
#=GS U4L9S0_PYROM/210-298        AC U4L9S0.1
#=GS A0A094E7D2_9PEZI/229-317    AC A0A094E7D2.1
#=GS F7CCK1_MACMU/56-145         AC F7CCK1.2
#=GS G5B0U6_HETGA/91-180         AC G5B0U6.1
#=GS A0A1B8DXH6_9PEZI/231-319    AC A0A1B8DXH6.1
#=GS F8VQM4_MOUSE/7-96           AC F8VQM4.1
#=GS A0A226N811_CALSU/57-145     AC A0A226N811.1
#=GS A0A0G2K0D5_RAT/52-141       AC A0A0G2K0D5.1
#=GS B6QTA5_TALMQ/228-316        AC B6QTA5.1
#=GS M7TIY4_BOTF1/227-315        AC M7TIY4.1
#=GS G3P0G3_GASAC/56-145         AC G3P0G3.1
#=GS A0A286ZL86_PIG/91-180       AC A0A286ZL86.1
#=GS H3CUX8_TETNG/24-119         AC H3CUX8.1
#=GS H2NVF7_PONAB/52-141         AC H2NVF7.1
#=GS H2M9X6_ORYLA/44-133         AC H2M9X6.1
#=GS W9W3W4_9EURO/227-315        AC W9W3W4.1
#=GS A0A2I3HR37_NOMLE/91-180     AC A0A2I3HR37.1
#=GS W2LMW5_PHYPR/56-149         AC W2LMW5.1
#=GS A0A0C3QVH5_9HOMO/22-108     AC A0A0C3QVH5.1
#=GS A0A2I0MIH1_COLLI/92-181     AC A0A2I0MIH1.1
#=GS A0A1I8H3Y8_9PLAT/101-191    AC A0A1I8H3Y8.1
#=GS OSB10_HUMAN/79-170          AC Q9BXB5.2
#=GS A0A1L8EWE6_XENLA/60-149     AC A0A1L8EWE6.1
#=GS G3NKG3_GASAC/98-187         AC G3NKG3.1
#=GS U1HRZ1_ENDPU/217-305        AC U1HRZ1.1
#=GS A0A2I3LMM2_PAPAN/91-180     AC A0A2I3LMM2.1
#=GS Q0UQ54_PHANO/203-291        AC Q0UQ54.2
#=GS A0A1S3P0E5_SALSA/76-165     AC A0A1S3P0E5.1
#=GS A0A178AFV5_9PLEO/221-309    AC A0A178AFV5.1
#=GS A0A2D0RAG5_ICTPU/56-145     AC A0A2D0RAG5.1
#=GS H2U4M2_TAKRU/2-91           AC H2U4M2.1
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F7EBN1_XENTR/92-181                    ...............GFMLK.K.R.K..W.P..LKGWHKRFFVL.--DN..GILKY...S....Ks.piDT...Q..KG...........KL....H.....G..S....I.D......V....G.....LS......V...M.....S.....I.......K....K....K...A..R...R........I..D...L.......D...T.......E.........E.........N.......I...YHLKVKSPDTFDAWVSKLRH--hr....................
#=GC SS_cons                           ...............XXXXX.X.X.X..X.X..X-S-EEEEEEE.ETTT..TEEEE...E....S....SS...S..--...........--....-.....E..E....E.E......G....G.....GS......E...E.....E.....E.......E....T....T...T..T...E........E..E...E.......E...-.......S.........S.........-.......E...EEEE-SSHHHHHHHHHHHHG--G.....................
#=GC seq_cons                          ...............GhLhK.+.R.+..h....hpGWt+RaFsL...cs..GhLpY...h....+....sp...p..st...........pl....+.....G..u....I.s......l....u.....Lu......l...h.....S.....s.......p....c....+...s..+...c........I..s...l.......D...o.......t.........p.........c.......l...aHLKspspc.FptWlstLcc..ph....................
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