KEGG ORTHOLOGY: K01388

ORTHOLOGY: K01388

Entry

K01388                      KO

Symbol

MMP1

Name

matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]

Pathway

map03320

PPAR signaling pathway

map04657

IL-17 signaling pathway

map04926

Relaxin signaling pathway

map05171

Coronavirus disease

map05200

Pathways in cancer

map05219

Bladder cancer

map05323

Rheumatoid arthritis

map05417

Lipid and atherosclerosis

Disease

H00028

Choriocarcinoma

H01714

Chronic obstructive pulmonary disease (COPD)

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
  09152 Endocrine system
   03320 PPAR signaling pathway
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
   04926 Relaxin signaling pathway
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
  09162 Cancer: specific types
   05219 Bladder cancer
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
  09172 Infectious disease: viral
   05171 Coronavirus disease
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
  09163 Immune disease
   05323 Rheumatoid arthritis
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
Enzymes [BR:ko01000]
3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.7  interstitial collagenase
     K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
Peptidases and inhibitors [BR:ko01002]
Metallo peptidases
  Family M10
   K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)

Genes

HSA:	4312(MMP1)

PTR:	451510(MMP1)

PPS:	100995251(MMP1)

GGO:	101131051(MMP1)

PON:	100459931(MMP1)

PPYG:

129008503(MMP1)

NLE:	100582292(MMP1)

HMH:	116476864(MMP1)

SSYN:

129479566(MMP1)

MCC:	703653(MMP1)

MCF:	102142258(MMP1)

MTHB:

126936364

MNI:	105493708(MMP1)

CSAB:

103248335(MMP1)

CATY:

105588779(MMP1)

PANU:

101000222(MMP1)

TGE:	112607316(MMP1)

MLEU:

105542743(MMP1)

RRO:	104674665(MMP1)

RBB:	108514074(MMP1)

TFN:	117081260(MMP1)

PTEH:

111540071(MMP1)

CANG:

105500944(MMP1)

CJC:	100400727(MMP1)

SBQ:	101051246(MMP1)

CIMI:

108315434(MMP1)

ANAN:

105719263(MMP1)

CSYR:

103277141(MMP1)

MMUR:

105871610 105874564(MMP1) 105874586

LCAT:

123641886(MMP1) 123641888

ERUF:

138383882 138384795

PCOQ:

105822159(MMP1)

OGA:	100951906(MMP1)

MMU:	83995(Mmp1a) 83996(Mmp1b)

MCAL:

110302197 110302562

MPAH:

110327208

RNO:	300338(Mmp1b) 300339(Mmp1)

MCOC:

116072562 116072563

ANU:	143439570 143439571 143439703

ASYL:

127690199 127690201

MMIU:

308430582(LOC308430582)

MUN:

CGE:

MAUA:

PROB:

PLEU:

114708012(Mmp1)

PMAV:

102906935(Mmp1)

MORG:

121451946

AAMP:

119810622

CNL:	130873440 130873697

NGI:	103731579 103731678

HGL:	101697620(Mmp1)

CPOC:

100727966

CCAN:

109689286(Mmp1)

DORD:

105980664(Mmp1)

DSP:	122110407(Mmp1)

DMER:

138809941 138824458

PLOP:

125348068(Mmp1)

NCAR:

124959000

SVUL:

306638701(MMP1)

MMMA:

107145904(Mmp1)

ITI:	101957438(Mmp1)

SCIL:

308642545(MMP1)

OCU:	100009110(MMP1)

OPI:	101527643(MMP1)

OCZ:	121154266(MMP1)

TUP:	102489479(MMP1) 102490608

GVR:

103610223

CFA:	489428(MMP1)

CLUD:

112671438(MMP1)

VVP:

112925907

VLG:	121500184(MMP1)

NPO:	129497337(MMP1)

AML:	100478167(MMP1) 100481181

UMR:	103662453(MMP1) 103662455

UAH:	113259797(MMP1) 130544561

UAR:	123792352(LOC123792352) 123792354(MMP1)

ELK:	111153766 111153845

LLV:	125078735 125078737

MPUF:

101688986(MMP1) 101689258

MNP:	132029154(MMP1) 132029164

MLK:	131834604 131834650

NVS:	122912251(MMP1) 122913961

ORO:	101369292 101371070

EJU:

114211360

ZCA:	113915492(MMP1)

MLX:

118013155

NSU:	110586222 110586384

LWW:	102733100(MMP1)

FCA:	101083957 101084217(MMP1)

PYU:	121020759 121020786

PCOO:

112865261 112865970(MMP1)

PBG:	122482471 122482878

PVIV:

125176694 125176877

LRUF:

124504840

LGF:	123602243 123602245

AJU:

106976487

PTG:	102951453 102970572(MMP1)

PPAD:

109257509 109257536

PUC:	125910773 125929798

PLEZ:

122200004(MMP1) 122200248

HHV:	120219691 120223090

CCRU:

144236087(MMP1) 144236288

BTA:	112441463 281308(MMP1)

BOM:	102264402 102282342(MMP1)

BIU:	109569224 109569225

BJV:	133261631(MMP1) 133261632

BBUB:

102402661 112579733 112579734(MMP1)

BKE:	129627995 129628003

BBIS:

104987807(MMP1)

CHX:	102170620(MMP1)

OAS:	101120355(MMP1)

OCAN:

138421069(MMP1)

BTAX:

128060537(MMP1)

CSUM:

138092400(MMP1)

ODA:	120876148(MMP1)

CCAD:

122449754 122450309

MREE:

136174262(MMP1)

OVR:	110141477(MMP1)

MBEZ:

129554246(MMP1) 129554918

SSC:	397320(MMP1)

CFR:	102517049(MMP1)

CBAI:

105067595(MMP1)

CDK:	105087169(MMP1)

VPC:	102528439(MMP1)

BACU:

103009752(MMP1)

BMUS:

118898730(MMP1)

LVE:	103089047(MMP1)

OOR:	101270980(MMP1)

LALB:

132525370(MMP1)

GMF:	115841564(MMP1)

DDP:

132428994

PCRS:

137229699(MMP1)

DLE:	111167568(MMP1)

PCAD:

102996438(MMP1)

PSIU:

116758693(MMP1)

PPHC:

136126671(MMP1)

NASI:

112394567

HAMP:

307056679(MMP1)

ECB:	100033896(MMP1)

EPZ:	103552636(MMP1)

EAI:	106843117(MMP1)

MYB:	102253167(MMP1)

MYD:	102770236(MMP1)

MMYO:

118664460(MMP1)

MLF:	102426724 102432629

MDT:	132240620(MMP1)

MYUM:

139018256(MMP1)

PKL:	118713253(MMP1)

EFUS:

103292965(MMP1)

POTS:

308234683(MMP1)

MNA:	107532387(MMP1)

DRO:	112317543(MMP1)

SHON:

118975722(MMP1)

AJM:	119054054(MMP1)

PDIC:

114499949(MMP1)

PHAS:

123805463(MMP1)

MMF:	118627979(MMP1)

PPAM:

129086095(MMP1)

HAI:

109376363

RFQ:	117031217(MMP1)

RHII:

308503229(LOC308503229)

PALE:

102893881(MMP1)

PVP:

105297437

RAY:	107504633(MMP1)

MJV:

108385449

TOD:	119240913(MMP1)

SARA:

101545391(MMP1)

SFUM:

130024322(MMP1)

SETR:

126016456(MMP1)

LAV:	100656422(MMP1)

TMU:

101341516

ETF:	101656920 101657534

DNM:	101411093(MMP1) 101432285

MDO:	100012472(MMP1)

GAS:

123238994

SHR:	100915062(MMP1)

AFZ:

PCW:

TVP:

PBRV:

OAA:

TACU:

GGA:	418982(MMP1)

PCOC:

116230604

MGP:	100543241(LOC100543241)

CJO:

TPAI:

LMUT:

NMEL:

APLA:

AACU:

OJA:

BCLA:

308448995(LOC308448995)

ACYG:

CATA:

AFUL:

TGU:

LSR:

VMC:

VCHA:

AIB:

SCAN:

PMOA:

OTC:

PRUF:

ATRC:

MATE:

MAEN:

GFR:	102045551(MMP1)

FAB:	101811360(MMP1)

OMA:

130251686

PHI:	102110938(LOC102110938)

PMAJ:

CCAE:

CCW:

CBRC:

ACOE:

ETL:

ZAB:

ZLE:

ACHL:

SVG:

MMEA:

LCAI:

146444933(LOC146444933)

HRT:

SATI:

CFAI:

CCIC:

NNT:

SHAB:

POCC:

PECH:

308219127(LOC308219127)

FPG:	101924590(MMP1)

FCH:

FRS:

CCRI:

ACUN:

ANOC:

SURA:

TALA:

ACHC:

HALD:

HLE:

AGEN:

HHAR:

BBUT:

GCL:

CSTI:

LDI:

MNB:

DPUB:

PPUS:

IIN:

AVIT:

BRHI:

EGZ:

NNI:

PLEC:

309601217(LOC309601217)

PCRI:

PCAO:

PARX:

PADL:

AFOR:

FGA:

CBOR:

GSTE:

CBOY:

MAME:

CLV:

CNIC:

NMAY:

308052421(LOC308052421)

MUI:

PGUU:

PLET:

EHS:

CMAC:

CUCA:

PCUR:

TEO:

BREG:

GAME:

OHA:

ACAR:

CEUR:

306717724(LOC306717724)

CPEA:

104390271

HEK:	139791917(LOC139791917)

CVF:

RTD:

CRID:

LMIC:

NARQ:

AAM:

AROW:

NPD:

TGT:

DNE:

SCAM:

ASN:	102387149 102387900 102388159

AMJ:	102563438(MMP8) 102563684(MMP1) 109281824

CPOO:

109306732 109306733 109306734

GGN:	109303295 109303296 109303297

CIZ:	142004236(MMP8) 142007030

CMY:

CCAY:

LKP:

NDS:

DCC:

CPIC:

TST:	117871172 117871174

CABI:

116814901

MRV:	120375402(LOC120375402) 120395357(LOC120395357)

EMQ:

137165730

ACS:	100552848 100553051

ASAO:

PVT:

SUND:

CTIG:

TSR:

PGUT:

PCAE:

APRI:

PTEX:

NSS:

VKO:

PMUA:

PRAF:

ZVI:

HCG:	128348708 128350400

GJA:

107119159

STOW:

125430822

EMC:	129325647 129326633

XLA:	108708733(mmp1.L) 495287(mmp1.S)

XTR:	594916(mmp1)

NPR:

RTEM:

ACAT:

PADS:

BBUF:

BGAR:

DTC:

PWL:	138248631 138248632

MUO:

115468492

BBEL:

109462004

DVV:	126880738 126880752 126880753 126880988 126882761 126883824 126883838 126885456 126886161 126890182 126890183

VEM:

105565628

OSN:

115222658

» show all

Reference

PMID:2167156

Authors

Templeton NS, Brown PD, Levy AT, Margulies IM, Liotta LA, Stetler-Stevenson WG

Title

Cloning and characterization of human tumor cell interstitial collagenase.

Journal

Cancer Res 50:5431-7 (1990)

Sequence

[hsa:4312]

Reference

PMID:19631700

Authors

Fanjul-Fernandez M, Folgueras AR, Cabrera S, Lopez-Otin C

Title

Matrix metalloproteinases: evolution, gene regulation and functional analysis in mouse models.

Journal

Biochim Biophys Acta 1803:3-19 (2010)
DOI:10.1016/j.bbamcr.2009.07.004

Reference

PMID:18060181

Authors

Amalinei C, Caruntu ID, Balan RA

Title

Biology of metalloproteinases.

Journal

Rom J Morphol Embryol 48:323-34 (2007)

All links

Gene (217)   
   MGENES (160)   
   RefGene (54)   
   OC (3)   
All databases (217)   

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