Cassia senna
Species
KNApSAcK Entry
| Organism name | Cassia senna |
|---|---|
| Genus | Cassia |
| Family | Fabaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Senna alexandrina |
|---|---|
| Linked NCBI taxonomy ID | 72402 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (4)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00000568
|
Chrysophanol
|
CHEMBL41092
|
C027113
|
20 / 17 / 20 | 1 / 0 | No. 41 | No. 62 |
|
|
C00002789
|
Aloe emodin
/ Rhabarberone |
CHEMBL40275
|
20 / 21 / 24 | No. 41 | No. 62 |
|
||
|
C00002861
|
Rhein
|
CHEMBL418068
|
C020491
|
60 / 65 / 46 | 8 / 1 | No. 1811 | No. 62 |
|
|
C00002863
|
Sennoside A
|
CHEMBL54481
CHEMBL448894 CHEMBL445268 CHEMBL1314924 CHEMBL1356785 CHEMBL1362935 CHEMBL1644069 |
58 / 59 / 53 | No. 7714 | No. 61 |
|
Human Protein / Gene in interactions
90 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000568 C00002789 C00002861 C00002863 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000568 C00002789 C00002861 C00002863 | 1 / 2 |
| O00255 | Menin | Unclassified protein | C00000568 C00002789 C00002861 C00002863 | 2 / 5 |
| P39748 | Flap endonuclease 1 | Enzyme | C00002789 C00002861 C00002863 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000568 C00002861 C00002863 | 4 / 3 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00000568 C00002861 C00002863 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00000568 C00002861 C00002863 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000568 C00002861 C00002863 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000568 C00002861 C00002863 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00002789 C00002861 C00002863 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000568 C00002861 C00002863 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000568 C00002861 C00002863 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000568 C00002861 C00002863 | 0 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00000568 C00002861 C00002863 | 2 / 3 |
| P03372 | Estrogen receptor | NR3A1 | C00002789 C00002861 C00002863 | 1 / 1 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00002789 C00002861 C00002863 | 0 / 1 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00002861 C00002863 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00002861 C00002863 | 3 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000568 C00002861 | 3 / 2 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00002861 C00002863 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000568 C00002861 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00002861 C00002863 | 11 / 10 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00000568 C00002863 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00002789 C00002861 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00002861 C00002863 | 1 / 2 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00002861 C00002863 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00002861 C00002863 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00002861 C00002863 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00000568 C00002863 | 4 / 2 |
| P09619 | Platelet-derived growth factor receptor beta | Pdgfr | C00002789 C00002861 | 5 / 1 |
| P08311 | Cathepsin G | S1A | C00002789 C00002861 | 0 / 0 |
| P08246 | Neutrophil elastase | S1A | C00002789 C00002861 | 2 / 1 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00002861 C00002863 | 1 / 1 |
| P16234 | Platelet-derived growth factor receptor alpha | Pdgfr | C00002789 C00002861 | 2 / 1 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00002861 C00002863 | 2 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00002861 C00002863 | 0 / 0 |
| P11308 | Transcriptional regulator ERG | Unclassified protein | C00002861 C00002863 | 1 / 2 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00002861 C00002863 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000568 C00002863 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002789 C00002861 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00000568 C00002861 | 0 / 1 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00002861 C00002863 | 0 / 0 |
| P55210 | Caspase-7 | C14 | C00002861 C00002863 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00002861 C00002863 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00002861 C00002863 | 2 / 1 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00000568 C00002861 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002861 C00002863 | 2 / 2 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000568 C00002863 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002861 C00002863 | 3 / 3 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00002861 | 0 / 0 |
| Q15149 | Plectin | Unclassified protein | C00002861 | 4 / 3 |
| P35236 | Tyrosine-protein phosphatase non-receptor type 7 | Tyr | C00002861 | 0 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00002863 | 1 / 1 |
| P10696 | Alkaline phosphatase, placental-like | Enzyme | C00002789 | 0 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00002863 | 0 / 0 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00002861 | 2 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00002863 | 1 / 1 |
| Q9H244 | P2Y purinoceptor 12 | Purine receptor | C00002789 | 1 / 1 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00002861 | 5 / 3 |
| Q99816 | Tumor susceptibility gene 101 protein | Unclassified protein | C00002861 | 0 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00002863 | 0 / 0 |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00002789 | 3 / 1 |
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00002789 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00002789 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00002789 | 3 / 4 |
| P10145 | Interleukin-8 | Secreted protein | C00002861 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00002863 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002863 | 0 / 0 |
| O00167 | Eyes absent homolog 2 | Enzyme | C00002863 | 0 / 0 |
| Q2TB90 | Putative hexokinase HKDC1 | Enzyme | C00002863 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00002861 | 0 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00002863 | 2 / 2 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002861 | 1 / 0 |
| Q9Y3R4 | Sialidase-2 | Enzyme | C00002861 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00002789 | 1 / 8 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00002863 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00002863 | 1 / 4 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00002861 | 1 / 0 |
| P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | C00002861 | 0 / 0 |
| P08238 | Heat shock protein HSP 90-beta | Other cytosolic protein | C00002861 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00002861 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00002863 | 0 / 3 |
| P19429 | Troponin I, cardiac muscle | Unclassified protein | C00002863 | 4 / 4 |
| P45379 | Troponin T, cardiac muscle | Unclassified protein | C00002863 | 3 / 5 |
| P63316 | Troponin C, slow skeletal and cardiac muscles | Other cytosolic protein | C00002863 | 2 / 2 |
| P63165 | Small ubiquitin-related modifier 1 | Unclassified protein | C00002863 | 1 / 1 |
| Q99700 | Ataxin-2 | Unclassified protein | C00002863 | 1 / 1 |
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00002863 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00002861 | 4 / 1 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00002863 | 1 / 1 |
8 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00000568
C00002861
|
| 4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00002861
|
| 2064 | ERBB2, CD340, HER-2, HER-2/neu, HER2, MLN_19, NEU, NGL, TKR1 | v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) |
C00002861
|
| 3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00002861
|
| 1950 | EGF, HOMG4, URG | epidermal growth factor |
C00002861
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00002861
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002861
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00002861
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (94)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #615007 | Basal ganglia calcification, idiopathic, 4; ibgc4 |
P09619
|
| #609821 | Bleeding disorder, platelet-type, 8; bdplt8 |
Q9H244
|
| #210900 | Bloom syndrome; blm |
P54132
|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #601494 | Cardiomyopathy, dilated, 1d; cmd1d |
P45379
|
| #613286 | Cardiomyopathy, dilated, 1ff; cmd1ff |
P19429
|
| #611879 | Cardiomyopathy, dilated, 1z; cmd1z |
P63316
|
| #611880 | Cardiomyopathy, dilated, 2a; cmd2a |
P19429
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #613243 | Cardiomyopathy, familial hypertrophic, 13; cmh13 |
P63316
|
| #115195 | Cardiomyopathy, familial hypertrophic, 2; cmh2 |
P45379
|
| #613690 | Cardiomyopathy, familial hypertrophic, 7; cmh7 |
P19429
|
| #115210 | Cardiomyopathy, familial restrictive, 1; rcm1 |
P19429
|
| #612422 | Cardiomyopathy, familial restrictive, 3; rcm3 |
P45379
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P18054
P84022 Q14191 |
| #162800 | Cyclic neutropenia |
P08246
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #226670 | Epidermolysis bullosa simplex with muscular dystrophy |
Q15149
|
| #612138 | Epidermolysis bullosa simplex with pyloric atresia |
Q15149
|
| #131950 | Epidermolysis bullosa simplex, ogna type |
Q15149
|
| #133239 | Esophageal cancer |
P18054
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #612219 | Ewing sarcoma; es |
P11308
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #606764 | Gastrointestinal stromal tumor; gist |
P16234
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P37231 |
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #607685 | Hypereosinophilic syndrome, idiopathic; hes |
P16234
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #146300 | Hypophosphatasia, adult |
P05186
|
| #241510 | Hypophosphatasia, childhood |
P05186
|
| #241500 | Hypophosphatasia, infantile |
P05186
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #607785 | Juvenile myelomonocytic leukemia; jmml |
P09619
|
| #601626 | Leukemia, acute myeloid; aml |
P09619
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #211980 | Lung cancer |
P00533
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #613723 | Muscular dystrophy, limb-girdle, type 2q; lgmd2q |
Q15149
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #131440 | Myeloproliferative disorder, chronic, with eosinophilia |
P09619
|
| #228550 | Myofibromatosis, infantile, 1; imf1 |
P09619
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P37231
|
| #613705 | Orofacial cleft 10; ofc10 |
P63165
|
| #167000 | Ovarian cancer |
P38398
|
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (74)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
|
| H00022 | Bladder cancer |
P00533
(related)
|
| H00028 | Choriocarcinoma |
P00533
(related)
|
| H00030 | Cervical cancer |
P00533
(related)
|
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P09619 (related) P16234 (related) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
P19429 (related) P45379 (related) P63316 (related) |
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
Q15149 (related) |
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
Q15149 (related) |
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
P45379 (related) |
| H00026 | Endometrial Cancer |
P03372
(marker)
Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00213 | Hypophosphatasia |
P05186
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00024 | Prostate cancer |
P10275
(related)
P11308 (related) |
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00023 | Testicular cancer |
P10696
(marker)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00035 | Ewing's sarcoma |
P11308
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00292 | Hypertrophic cardiomyopathy (HCM) |
P19429
(related)
P45379 (related) P63316 (related) |
| H01219 | Restrictive cardiomyopathy (RCM) |
P19429
(related)
P45379 (related) |
| H00295 | Viral myocarditis |
P19429
(marker)
P45379 (marker) |
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00032 | Thyroid cancer |
P37231
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00027 | Ovarian cancer |
P38398
(related)
|
| H00031 | Breast cancer |
P38398
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
| H00516 | Isolated orofacial clefts |
P63165
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00585 | Epidermolysis bullosa, hemidesmosomal |
Q15149
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H01235 | Bleeding disorder platelet-type |
Q9H244
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|