Species

KNApSAcK Entry

Organism name Erythrina vogelii
Genus Erythrina
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Erythrina
Linked NCBI taxonomy ID 3841
Linked level genus

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (25)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00019046 External link 512 Isolupalbigenin
CHEMBL461061
2 / 1 / 1 No. 14 No. 15
C00009940 External link 512 8-Prenylluteone
/ 5,7,2',4'-Tetrahydroxy-6,8-diprenylisoflavone
No. 14 No. 15
C00019284 External link 512 Vogelin C
/ 5,7,2',4'-Tetrahydroxy-8,5'-diprenylisoflavone
No. 14 No. 15
C00009516 External link 512 6,8-Diprenylgenistein
/ 8-(gamma,gamma-Dimethylallyl)wighteone
/ 5,7,4'-Trihydroxy-6,8-diprenylisoflavone
CHEMBL494252
12 / 14 / 11 No. 14 No. 15
C00004089 External link 512 6-Prenylapigenin
/ 6-C-Prenylapigenin
/ 5,7,4'-Trihydroxy-6-prenylflavone
/ 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
No. 15 No. 15
C00019044 External link 512 Vogelin F
/ 5,7,4'-Trihydroxy-2-methoxy-5'-prenylisoflavone
CHEMBL461270
No. 15 No. 15
C00009831 External link 512 Isowighteone
/ 3'-Prenylgenistein
/ 5,7,4'-Trihydroxy-3'-prenylisoflavone
CHEMBL464460
2 / 1 / 1 No. 15 No. 15
C00019043 External link 512 Vogelin E
/ (2E)-5,7,4'-Trihydroxy-3'-(4-hydroxy-3-methyl-2-butenyl)isoflavone
CHEMBL459026
No. 15 No. 15
C00009915 External link 512 Isochandalone
/ 5,7-Dihydroxy-6-prenyl-6'',6''-dimethylpyrano[2'',3'':4',3']isoflavone
CHEMBL460441
No. 18 No. 15
C00009521 External link 512 Auriculatin
No. 18 No. 15
C00034916 External link 512 Vogelin I
/ (+)-Vogelin I
No. 18 No. 15
C00009514 External link 512 Scandenone
/ Warangalone
CHEMBL458134
C105205
No. 18 No. 15
C00009935 External link 512 Ulexone A
/ 5,7-Dihydroxy-8-prenyl-6'',6''-dimethylpyrano[2'',3'':4',3']isoflavone
CHEMBL461062
No. 18 No. 15
C00019042 External link 512 Vogelin D
/ (3R)-5,7-Dihydroxy-4'-methoxy-6,3'-diprenylisoflavanone
CHEMBL514443
No. 19 No. 14
C00013432 External link 512 Carpachromene
/ 5,4'-Dihidroxy-6'',6''-dimethylpyrano[2'',3'':7,6]flavone
/ 5-Hydroxy-8-(4-hydroxyphenyl)-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one
No. 24 No. 15
C00034917 External link 512 Vogelin J
No. 24 No. 15
C00004052 External link 512 Limonianin
/ Atalantoflavone
CHEMBL465808
No. 24 No. 15
C00009873 External link 512 Isoderrone
/ 5,7-Dihydroxy-6'',6''-dimethylpyrano[2'',3'':4',3']isoflavone
No. 24 No. 15
C00019058 External link 512 Vogelin A
/ 5,7,2'-Trihydroxy-4'-methoxy-5'-prenylisoflavone
No. 28 No. 14
C00018933 External link 512 Vogelin B
/ Erypoegin C
/ 5,7,4'-Trihydroxy-2'-methoxy-5'-prenylisoflavanone
No. 28 No. 14
C00009971 External link 512 2,3-Dihydroauriculatin
/ 5,2',4'-Trihydroxy-8-prenyl-6'',6''-dimethylpyrano[2'',3'':7,6]isoflavanone
C050248
No. 39
C00034915 External link 512 Vogelin H
/ (-)-Vogelin H
No. 47 No. 15
C00019045 External link 512 Vogelin G
/ 4'',5''-Dihydro-5,7-dihydroxy-3'-prenyl-6'',6''-dimethylpyrano[2'',3'':4',5']isoflavone
CHEMBL518341
No. 47 No. 15
C00019007 External link 512 Ficuisoflavone
CHEMBL459025
No. 139
C00009654 External link 512 1-Methoxyphaseollidin
/ 3,9-Dihydroxy-1-methoxy-10-prenylpterocarpan
CHEMBL1726462
5 / 4 / 2 No. 188 No. 15

Human Protein / Gene in interactions

15 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00009516 C00009654 1 / 1
O75164 Lysine-specific demethylase 4A Enzyme C00009516 C00009654 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00009516 C00009654 2 / 0
P03372 Estrogen receptor NR3A1 C00009831 C00019046 1 / 1
Q92731 Estrogen receptor beta NR3A2 C00009831 C00019046 0 / 1
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00009516 C00009654 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00009516 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00009654 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00009516 0 / 0
O75496 Geminin Unclassified protein C00009516 0 / 0
P04062 Glucosylceramidase Enzyme C00009516 6 / 4
P10636 Microtubule-associated protein tau Unclassified protein C00009516 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00009516 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00009516 1 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00009516 0 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (16)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P84022
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#137800 Glioma susceptibility 1; glm1 O75874
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (13)

KEGG name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00026 Endometrial Cancer P03372 (marker)
Q92731 (marker)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)