Species

KNApSAcK Entry

Organism name Justicia diffusa var. prostrata
Genus Justicia
Family Acanthaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Justicia
Linked NCBI taxonomy ID 4190
Linked level genus

Family

Family in NCBI taxonomy Acanthaceae
ID 4185

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00007190 External link 512 (+)-Pinoresinol
CHEMBL267963
CHEMBL487611
CHEMBL460862
C103298
7 / 5 / 6 No. 38 No. 21
C00000659 External link 512 Medioresinol
/ (+)-Medioresinol
CHEMBL376507
CHEMBL513023
2 / 1 / 1 No. 38 No. 21
C00000700 External link 512 Justicidin A
CHEMBL508532
C049719
No. 285 No. 21
C00007211 External link 512 Helioxanthin
CHEMBL436474
No. 285 No. 21
C00007204 External link 512 Isolariciresinol
/ (+)-Isolariciresinol
CHEMBL399512
CHEMBL1760593
C060284
2 / 1 / 1 No. 406
C00002591 External link 512 (-)-Cubebin
/ beta-Cubebin
/ (-)-beta-Cubebin
/ (8R,8'R,9S)-Cubebin
CHEMBL182001
CHEMBL399831
C433065
2 / 1 / 1 0 / 2 No. 629 No. 21
C00000602 External link 512 (+)-Lariciresinol
CHEMBL518421
2 / 1 / 1 No. 700 No. 21

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000602 C00000659 C00002591 C00007204 1 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000602 C00000659 C00002591 C00007204 0 / 1
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00007190 5 / 3
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00007190 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00007190 0 / 3
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00007190 0 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00007190 0 / 0
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00007190 0 / 0
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00007190 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#608902 Drug metabolism, poor, cyp2d6-related P10635
#137800 Glioma susceptibility 1; glm1 P37231
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#601665 Obesity P37231

KEGG DISEASE (7)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D004487 Edema C00002591
D010146 Pain C00002591