Sambucus nigra

• Index
• Plant Species
• Natural Activity
• Metabolite list (14)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Sambucus nigra
Genus	Sambucus
Family	Adoxaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Sambucus nigra
Linked NCBI taxonomy ID	4202
Linked level	species

Family

Family in NCBI taxonomy	Adoxaceae
ID	4206

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Natural Activity

List (20)

Species	Activity
Sambucus nigra L.	Alterative
Sambucus nigra L.	Analgesic
Sambucus nigra L.	Antiinflammatory
Sambucus nigra L.	Antipyretic
Sambucus nigra L.	Antiviral
Sambucus nigra L.	Bronchodilator
Sambucus nigra L.	Carminative
Sambucus nigra L.	Depurative
Sambucus nigra L.	Diaphoretic
Sambucus nigra L.	Diuretic
Sambucus nigra L.	Emetic
Sambucus nigra L.	Emollient
Sambucus nigra L.	Expectorant
Sambucus nigra L.	Lactagogue
Sambucus nigra L.	Laxative
Sambucus nigra L.	Mcolytic
Sambucus nigra L.	Phagocytotic
Sambucus nigra L.	Secretagogue
Sambucus nigra L.	Stimulant
Sambucus nigra L.	Stomachic

Metabolite list (14)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00005506	Rhamnetin 3-glucoside
C00006673	Cyanidin 3-sambubioside-5-glucoside					No. 5	No. 15
C00000659	Medioresinol / (+)-Medioresinol	CHEMBL376507 CHEMBL513023		2 / 1 / 1		No. 38	No. 21
C00007190	(+)-Pinoresinol	CHEMBL267963 CHEMBL487611 CHEMBL460862	C103298	7 / 5 / 6		No. 38	No. 21
C00037273	Holocalin					No. 45	No. 72
C00001460	Zierin					No. 45	No. 72
C00001454	Prunasin / (-)-Prunasin / (2R)-Prunasin / (-)-(2R)-Prunasin	CHEMBL1778417				No. 45	No. 72
C00034206	Sambunigrin / (S)-Prunasin / (2S)-Sambunigrin	CHEMBL1778417				No. 45	No. 72
C00003647	Campesterol / 24alpha-Methylcholesterol / (24R)24-Methylcholest-5-en-3beta-ol	CHEMBL520535 CHEMBL485421 CHEMBL1836653	C021273			No. 53	No. 11
C00031877	Icariside F2 / Benzyl beta-D-Apiofuranosyl-(1->6)-O-beta-D-glucopyranoside					No. 267
C00003772	Flavoxanthin					No. 664	No. 59
C00000602	(+)-Lariciresinol	CHEMBL518421		2 / 1 / 1		No. 700	No. 21
C00002718	1-Caffeoyl-beta-D-glucose	CHEMBL482242				No. 1127	No. 6
C00037426	L-Mandelic acid / L-(+)-Mandelic acid	CHEMBL58910 CHEMBL292411 CHEMBL1609		12 / 15 / 11		No. 2481

Human Protein / Gene in interactions

21 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000602 C00000659	1 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000602 C00000659	0 / 1
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00007190	5 / 3
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00007190	0 / 3
P04406	Glyceraldehyde-3-phosphate dehydrogenase	Enzyme	C00037426	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00007190	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00037426	11 / 10
P14902	Indoleamine 2,3-dioxygenase 1	Enzyme	C00037426	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00037426	2 / 0
P08107	Heat shock 70 kDa protein 1A/1B	Unclassified protein	C00037426	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00007190	0 / 0
P35236	Tyrosine-protein phosphatase non-receptor type 7	Tyr	C00037426	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00007190	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00037426	0 / 0
P98170	E3 ubiquitin-protein ligase XIAP	Other cytosolic protein	C00037426	1 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00037426	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00007190	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00037426	0 / 0
P11142	Heat shock cognate 71 kDa protein	Unclassified protein	C00037426	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00037426	1 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00007190	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions