Daphne genkwa

• Index
• Plant Species
• Metabolite list (7)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Daphne genkwa
Genus	Daphne
Family	Thymelaeaceae
Kingdom	Plantae

---

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Daphne
Linked NCBI taxonomy ID	66679
Linked level	genus

Family

Family in NCBI taxonomy	Thymelaeaceae
ID	39987

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (7)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001043	Genkwanin	CHEMBL210635	C014568	5 / 4 / 5	3 / 0	No. 3	No. 15
C00007190	(+)-Pinoresinol	CHEMBL267963 CHEMBL487611 CHEMBL460862	C103298	7 / 5 / 6		No. 38	No. 21
C00000606	(-)-Matairesinol	CHEMBL425148	C068935	1 / 0 / 0		No. 223	No. 21
C00000604	(-)-Secoisolariciresinol	CHEMBL368347	C060283	2 / 1 / 1	1 / 0	No. 282	No. 21
C00000602	(+)-Lariciresinol	CHEMBL518421		2 / 1 / 1		No. 700	No. 21
C00008958	Genkwanol B					No. 2864
C00008959	Genkwanol C					No. 2864

Human Protein / Gene in interactions

15 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000602 C00000604	1 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000602 C00000604	0 / 1
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00007190	5 / 3
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00007190	0 / 0
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00001043	0 / 0
Q9Y3R4	Sialidase-2	Enzyme	C00001043	0 / 0
P04278	Sex hormone-binding globulin	Secreted protein	C00000606	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00007190	0 / 3
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00001043	4 / 4
P04745	Alpha-amylase 1	Enzyme	C00001043	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00007190	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00007190	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00007190	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00001043	0 / 1
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00007190	0 / 0

4 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00001043
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00001043
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00001043
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00000604

Related Diseases

Diseases related to proteins in ChEMBL interactions