Xylocarpus granatum

• Index
• Plant Species
• Metabolite list (67)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Xylocarpus granatum
Genus	Xylocarpus
Family	Meliaceae
Kingdom	Plantae

---

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Xylocarpus granatum
Linked NCBI taxonomy ID	241841
Linked level	species

Family

Family in NCBI taxonomy	Meliaceae
ID	43707

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (67)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00000947	D-Catechol / D-Catechin / Teafuran 30A / (+)-Catechin / Dexcyanidanol / (+)-3',4',5,7-Tetrahydroxy-2,3-trans-flavan-3-ol	CHEMBL80941 CHEMBL311498 CHEMBL129482 CHEMBL200715 CHEMBL206452 CHEMBL583912	D002392	85 / 58 / 54	91 / 13	No. 52	No. 14
C00048205	Tigloylseneganolide A					No. 102
C00040073	Proceranolide	CHEMBL1081393				No. 102
C00047911	Granatumin D / (-)-Granatumin D					No. 102
C00047909	Granatumin B / (+)-Granatumin B					No. 102
C00047908	Granatumin A / (+)-Granatumin A					No. 102
C00037373	Khayasin T					No. 102
C00047910	Granatumin C / (+)-Granatumin C					No. 102
C00024641	Dihydrochelerythrine / 12,13-Dihydrochelerythrine	CHEMBL400359				No. 195	No. 4
C00040717	Xylocarpin I / (+)-Xylocarpin I					No. 196
C00047901	Gedunin	CHEMBL465226 CHEMBL1335340 CHEMBL2004035	C106014	16 / 33 / 55	83 / 1	No. 204	No. 51
C00034343	Xyloccensin K	CHEMBL1082138 CHEMBL1966058				No. 255
C00032531	Xyloccensin Q					No. 378
C00032530	Xyloccensin P					No. 378
C00047913	Granatumin F / (+)-Granatumin F					No. 378
C00047914	Granatumin G / (+)-Granatumin G					No. 378
C00035430	Xyloccensin R / (+)-Xyloccensin R					No. 378
C00048236	Xyloccensin O					No. 378
C00035432	Xyloccensin T / (+)-Xyloccensin T					No. 378
C00035431	Xyloccensin S / (+)-Xyloccensin S					No. 378
C00047790	Chisocheton F	CHEMBL1079490 CHEMBL1774404				No. 453
C00019308	Doursterol / Daucosterin / 3-O-beta-D-Glucopyranosyl sitosterol / beta-Sitosterol 3-O-beta-D-glucopyranoside	CHEMBL197711 CHEMBL506678 CHEMBL2304043	C011015	5 / 4 / 2	0 / 3	No. 520
C00024103	Swietemahonolide					No. 535
C00039289	Granaxylocarpin C / (-)-Granaxylocarpin C	CHEMBL388137				No. 535
C00002189	N-Methylflindersine	CHEMBL400130				No. 799	No. 7
C00000856	4-Hydroxybenzoic acid / p-Hydroxybenzoic acid	CHEMBL441343	C038193	21 / 7 / 16	2 / 1	No. 817	No. 81
C00040710	Xylocarpin B					No. 833
C00040709	Xylocarpin A	CHEMBL388296				No. 833
C00040711	Xylocarpin C					No. 833
C00040712	Xylocarpin D	CHEMBL225041				No. 833
C00040713	Xylocarpin E					No. 833
C00041971	Xyloccensin Z2					No. 833
C00041970	Xyloccensin Z1					No. 833
C00035433	Xyloccensin U					No. 833
C00039290	Granaxylocarpin D	CHEMBL225041				No. 833
C00040715	Xylocarpin G					No. 873
C00032532	Xylogranatin A					No. 873
C00040714	Xylocarpin F	CHEMBL1555153		8 / 17 / 44		No. 873
C00048918	Xylogranatin L / (-)-Xylogranatin L					No. 975
C00048917	Xylogranatin K / (-)-Xylogranatin K					No. 975
C00048916	Xylogranatin J / (-)-Xylogranatin J					No. 975
C00048919	Xylogranatin M / (-)-Xylogranatin M					No. 975
C00048922	Xylogranatin P / (-)-Xylogranatin P					No. 975
C00048921	Xylogranatin O / (-)-Xylogranatin O					No. 975
C00048915	Xylogranatin I / (-)-Xylogranatin I					No. 975
C00048923	Xylogranatin Q / (-)-Xylogranatin Q					No. 975
C00048920	Xylogranatin N / (-)-Xylogranatin N					No. 975
C00048072	Protoxylocarpin H	CHEMBL1075702				No. 1247
C00048070	Protoxylocarpin F	CHEMBL1075700 CHEMBL1075701				No. 1247
C00048071	Protoxylocarpin G	CHEMBL1075700 CHEMBL1075701				No. 1247
C00003368	Spicatin					No. 1532	No. 38
C00032950	Ethyl protocatechuate / Ethyl 3,4-dihydroxybenzoate	CHEMBL486216	C018063	7 / 3 / 5		No. 1722
C00039288	Granaxylocarpin B / (-)-Granaxylocarpin B	CHEMBL390119				No. 1754
C00032535	Xylogranatin D					No. 1754
C00039287	Granaxylocarpin A / (+)-Granaxylocarpin A	CHEMBL389681				No. 1754
C00032533	Xylogranatin B					No. 1754
C00040716	Xylocarpin H / (+)-Xylocarpin H	CHEMBL390119				No. 1754
C00032534	Xylogranatin C					No. 1754
C00041367	Aurantiamide	CHEMBL475827				No. 2605
C00003170	Phaseic acid					No. 2610	No. 38
C00048913	Xylogranatin G / (+)-Xylogranatin G					No. 4179
C00048912	Xylogranatin F / (+)-Xylogranatin F					No. 4179
C00048914	Xylogranatin H / (+)-Xylogranatin H					No. 4179
C00047912	Granatumin E / (-)-Granatumin E					No. 5312
C00047876	Febrifugin A					No. 5312
C00048924	Xylogranatin R / (+)-Xylogranatin R					No. 6267
C00048237	Xylogranatinin					No. 8323

Human Protein / Gene in interactions

108 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P00918	Carbonic anhydrase 2	Lyase	C00000856 C00000947 C00032950	1 / 2
P11473	Vitamin D3 receptor	NR1I1	C00000947 C00040714 C00047901	2 / 3
Q9ULX7	Carbonic anhydrase 14	Lyase	C00000856 C00000947 C00032950	0 / 0
O43570	Carbonic anhydrase 12	Lyase	C00000856 C00000947 C00032950	1 / 2
Q16637	Survival motor neuron protein	Unclassified protein	C00000947 C00040714 C00047901	4 / 1
P00915	Carbonic anhydrase 1	Lyase	C00000856 C00000947 C00032950	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000947 C00040714 C00047901	4 / 3
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000947 C00040714 C00047901	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000947 C00040714 C00047901	0 / 1
Q16790	Carbonic anhydrase 9	Lyase	C00000856 C00000947 C00032950	0 / 1
P43166	Carbonic anhydrase 7	Lyase	C00000856 C00000947 C00032950	0 / 0
P00734	Prothrombin	S1A	C00000947 C00019308	4 / 2
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00000856 C00000947	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00000856 C00000947	0 / 0
P06746	DNA polymerase beta	Enzyme	C00000947 C00019308	0 / 0
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00000947 C00047901	1 / 0
P07451	Carbonic anhydrase 3	Lyase	C00000856 C00000947	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000947 C00047901	2 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00040714 C00047901	7 / 37
P22748	Carbonic anhydrase 4	Lyase	C00000856 C00000947	1 / 1
P23280	Carbonic anhydrase 6	Lyase	C00000856 C00000947	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00000947 C00040714	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00000947 C00019308	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00000947	5 / 1
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00000947	1 / 1
P02768	Serum albumin	Secreted protein	C00000947	0 / 0
P49327	Fatty acid synthase	Transferase	C00000947	0 / 0
Q9UQ49	Sialidase-3	Enzyme	C00000856	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000947	0 / 1
Q9GZT9	Egl nine homolog 1	Enzyme	C00032950	1 / 1
P54132	Bloom syndrome protein	Enzyme	C00000947	1 / 2
Q9HAW7	UDP-glucuronosyltransferase 1-7	Enzyme	C00000856	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000856	1 / 8
P11388	DNA topoisomerase 2-alpha	Isomerase	C00000947	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00000947	3 / 2
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000947	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000947	0 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00019308	0 / 0
Q9Y3R4	Sialidase-2	Enzyme	C00000947	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00047901	11 / 10
P00352	Retinal dehydrogenase 1	Enzyme	C00000947	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00040714	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00000947	0 / 0
P07998	Ribonuclease pancreatic	Enzyme	C00000947	0 / 0
P28907	ADP-ribosyl cyclase 1	Enzyme	C00000947	0 / 1
O75496	Geminin	Unclassified protein	C00047901	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00000856	0 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000947	0 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00000947	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00019308	0 / 0
P07711	Cathepsin L1	C1A	C00000947	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00047901	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00000947	1 / 1
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00000947	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00000947	3 / 1
P52209	6-phosphogluconate dehydrogenase, decarboxylating	Enzyme	C00000947	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00000947	1 / 1
P80404	4-aminobutyrate aminotransferase, mitochondrial	Transferase	C00000856	1 / 1
P04745	Alpha-amylase 1	Enzyme	C00000947	0 / 0
P08581	Hepatocyte growth factor receptor	TK tyrosine-protein kinase MET subfamily	C00000947	2 / 3
P28482	Mitogen-activated protein kinase 1	Erk	C00000947	0 / 0
P10696	Alkaline phosphatase, placental-like	Enzyme	C00000947	0 / 1
P56817	Beta-secretase 1	A1A	C00000947	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000947	0 / 0
Q13093	Platelet-activating factor acetylhydrolase	Enzyme	C00000947	3 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000947	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000947	2 / 2
Q01453	Peripheral myelin protein 22	Unclassified protein	C00000947	5 / 2
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00047901	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00000856	0 / 0
P00374	Dihydrofolate reductase	Oxidoreductase	C00000947	1 / 1
P35372	Mu-type opioid receptor	Opioid receptor	C00000947	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00000947	0 / 0
P08238	Heat shock protein HSP 90-beta	Other cytosolic protein	C00047901	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00000947	0 / 0
P51580	Thiopurine S-methyltransferase	Enzyme	C00000856	1 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000947	1 / 1
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000947	0 / 3
Q9UNA4	DNA polymerase iota	Enzyme	C00000947	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00047901	1 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000947	0 / 0
P51649	Succinate-semialdehyde dehydrogenase, mitochondrial	Oxidoreductase	C00000856	1 / 1
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00000856	0 / 0
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00000856	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00047901	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00000947	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000947	1 / 0
P10415	Apoptosis regulator Bcl-2	Other cytosolic protein	C00000947	0 / 7
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00000947	3 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000947	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000947	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000947	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000947	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00047901	1 / 0
O00255	Menin	Unclassified protein	C00000947	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000947	1 / 2
Q05513	Protein kinase C zeta type	Iota	C00000947	0 / 0
Q04759	Protein kinase C theta type	Delta	C00000947	0 / 1
Q02156	Protein kinase C epsilon type	Eta	C00000947	0 / 0
O94806	Serine/threonine-protein kinase D3	Pkd	C00000947	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000947	0 / 0
Q05655	Protein kinase C delta type	Delta	C00000947	0 / 0
P05129	Protein kinase C gamma type	Alpha	C00000947	1 / 1
P05771	Protein kinase C beta type	Alpha	C00000947	0 / 0
P24723	Protein kinase C eta type	Eta	C00000947	1 / 0
P41743	Protein kinase C iota type	Iota	C00000947	0 / 0
Q15139	Serine/threonine-protein kinase D1	Pkd	C00000947	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00000947	0 / 0

169 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00000856 C00000947
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00000947 C00047901
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000947 C00047901
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00000947 C00047901
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00000947 C00047901
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000947 C00047901
694	BTG1	B-cell translocation gene 1, anti-proliferative	C00000947 C00047901
3683	ITGAL, CD11A, LFA-1, LFA1A	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	C00000947
9531	BAG3, BAG-3, BIS, CAIR-1, MFM6	BCL2-associated athanogene 3	C00047901
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00047901
84159	ARID5B, DESRT, MRF-2, MRF2	AT rich interactive domain 5B (MRF1-like)	C00047901
8209	C21orf33, ES1, GT335, HES1, KNPH, KNPI	chromosome 21 open reading frame 33	C00047901
27101	CACYBP, GIG5, RP1-102G20.6, S100A6BP, SIP	calcyclin binding protein	C00047901
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00047901
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00047901
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00047901
874	CBR3, SDR21C2, hCBR3	carbonyl reductase 3 (EC:1.1.1.184)	C00047901
8317	CDC7, CDC7L1, HsCDC7, Hsk1, huCDC7	cell division cycle 7 (EC:2.7.11.1)	C00047901
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00047901
26973	CHORDC1, CHP1	cysteine and histidine-rich domain (CHORD) containing 1	C00047901
10370	CITED2, ASD8, MRG-1, MRG1, P35SRJ, VSD2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	C00047901
10598	AHSA1, AHA1, C14orf3, p38	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	C00047901
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00047901
54541	DDIT4, Dig2, REDD-1, REDD1	DNA-damage-inducible transcript 4	C00047901
3301	DNAJA1, DJ-2, DjA1, HDJ2, HSDJ, HSJ2, HSPF4, NEDD7, hDJ-2	DnaJ (Hsp40) homolog, subfamily A, member 1	C00047901
11080	DNAJB4, DNAJW, DjB4, HLJ1	DnaJ (Hsp40) homolog, subfamily B, member 4	C00047901
1948	EFNB2, EPLG5, HTKL, Htk-L, LERK5	ephrin-B2	C00047901
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00047901
11153	FICD, HIP13, HYPE, UNQ3041	FIC domain containing (EC:2.7.7.n1)	C00047901
2322	FLT3, CD135, FLK-2, FLK2, STK1	fms-related tyrosine kinase 3 (EC:2.7.10.1)	C00047901
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00047901
9518	GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB	growth differentiation factor 15	C00047901
54676	GTPBP2	GTP binding protein 2	C00047901
29923	HILPDA, C7orf68, HIG-2, HIG2	hypoxia inducible lipid droplet-associated	C00047901
3157	HMGCS1, HMGCS	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) (EC:2.3.3.10)	C00047901
3952	LEP, LEPD, OB, OBS	leptin	C00000856
3320	HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	C00047901
3303	HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1	heat shock 70kDa protein 1A	C00047901
3304	HSPA1B, HSP70-1B, HSP70-2	heat shock 70kDa protein 1B	C00047901
3309	HSPA5, BIP, GRP78, MIF2	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	C00047901
10808	HSPH1, HSP105, HSP105A, HSP105B, NY-CO-25	heat shock 105kDa/110kDa protein 1	C00047901
3557	IL1RN, DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4	interleukin 1 receptor antagonist	C00047901
3638	INSIG1, CL-6, CL6	insulin induced gene 1	C00047901
182	JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1	jagged 1	C00047901
3781	KCNN2, KCa2.2, SK2, SKCA2, SKCa_2, hSK2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	C00047901
3949	LDLR, FH, FHC, LDLCQ2	low density lipoprotein receptor	C00047901
23175	LPIN1, PAP1	lipin 1 (EC:3.1.3.4)	C00047901
26046	LTN1, C21orf10, C21orf98, RNF160, ZNF294	listerin E3 ubiquitin protein ligase 1	C00047901
9935	MAFB, KRML, MCTO	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B	C00047901
4191	MDH2, M-MDH, MDH, MGC:3559, MOR1	malate dehydrogenase 2, NAD (mitochondrial) (EC:1.1.1.37)	C00047901
4199	ME1, HUMNDME, MES	malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40)	C00047901
4335	MNT, MAD6, MXD6, ROX, bHLHd3	MAX network transcriptional repressor	C00047901
29074	MRPL18, L18mt, MRP-L18	mitochondrial ribosomal protein L18	C00047901
2956	MSH6, GTBP, GTMBP, HNPCC5, HSAP, p160	mutS homolog 6	C00047901
6307	MSMO1, DESP4, ERG25, SC4MOL	methylsterol monooxygenase 1 (EC:1.14.13.72)	C00047901
23077	MYCBP2, PAM	MYC binding protein 2, E3 ubiquitin protein ligase	C00047901
55892	MYNN, OSZF, ZBTB31, ZNF902	myoneurin	C00047901
4683	NBN, AT-V1, AT-V2, ATV, NBS, NBS1, P95	nibrin	C00047901
4824	NKX3-1, BAPX2, NKX3, NKX3.1, NKX3A	NK3 homeobox 1	C00047901
9315	NREP, C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17	neuronal regeneration related protein	C00047901
4986	OPRK1, K-OR-1, KOR, KOR-1, OPRK	opioid receptor, kappa 1	C00047901
51526	OSER1, C20orf111, HSPC207, Osr1, Perit1, dJ1183I21.1	oxidative stress responsive serine-rich 1	C00047901
5152	PDE9A, HSPDE9A2	phosphodiesterase 9A (EC:3.1.4.35)	C00047901
5293	PIK3CD, P110DELTA, PI3K, p110D	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta (EC:2.7.1.153)	C00047901
5295	PIK3R1, AGM7, GRB1, p85, p85-ALPHA	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	C00047901
10105	PPIF, CYP3, CyP-M, Cyp-D, CypD	peptidylprolyl isomerase F (EC:5.2.1.8)	C00047901
5813	PURA, PUR-ALPHA, PUR1, PURALPHA	purine-rich element binding protein A	C00047901
6241	RRM2, R2, RR2, RR2M	ribonucleotide reductase M2 (EC:1.17.4.1)	C00047901
27230	SERP1, RAMP4	stress-associated endoplasmic reticulum protein 1	C00047901
27244	SESN1, PA26, SEST1	sestrin 1	C00047901
6520	SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE	solute carrier family 3 (amino acid transporter heavy chain), member 2	C00047901
23657	SLC7A11, CCBR1, xCT	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	C00047901
79811	SLTM, Met	SAFB-like, transcription modulator	C00047901
6659	SOX4, EVI16	SRY (sex determining region Y)-box 4	C00047901
100380807			C00047901
10963	STIP1, HOP, IEF-SSP-3521, P60, STI1, STI1L	stress-induced-phosphoprotein 1	C00047901
51347	TAOK3, DPK, JIK, MAP3K18	TAO kinase 3 (EC:2.7.11.1)	C00047901
7113	TMPRSS2, PP9284, PRSS10	transmembrane protease, serine 2 (EC:3.4.21.-)	C00047901
10628	TXNIP, EST01027, HHCPA78, THIF, VDUP1	thioredoxin interacting protein	C00047901
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00047901
7320	UBE2B, E2-17kDa, HHR6B, HR6B, RAD6B, UBC2	ubiquitin-conjugating enzyme E2B (EC:6.3.2.19)	C00047901
7358	UGDH, GDH, UDP-GlcDH, UDPGDH, UGD	UDP-glucose 6-dehydrogenase (EC:1.1.1.22)	C00047901
79084	WDR77, MEP-50, MEP50, Nbla10071, RP11-552M11.3, p44, p44/Mep50	WD repeat domain 77	C00047901
23099	ZBTB43, ZBTB22B, ZNF-X, ZNF297B	zinc finger and BTB domain containing 43	C00047901
80149	ZC3H12A, MCPIP, MCPIP1, RP3-423B22.1, dJ423B22.1	zinc finger CCCH-type containing 12A	C00047901
9429	ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1	ATP-binding cassette, sub-family G (WHITE), member 2	C00000947
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000947
302	ANXA2, ANX2, ANX2L4, CAL1H, LIP2, LPC2, LPC2D, P36, PAP-IV	annexin A2	C00000947
393	ARHGAP4, C1, RGC1, RhoGAP4, SrGAP4, p115	Rho GTPase activating protein 4	C00000947
468	ATF4, CREB-2, CREB2, TAXREB67, TXREB	activating transcription factor 4	C00000947
472	ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1	ataxia telangiectasia mutated (EC:2.7.11.1)	C00000947
2683	B4GALT1, B4GAL-T1, CDG2D, GGTB2, GT1, GTB, beta4Gal-T1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (EC:2.4.1.22 2.4.1.90 2.4.1.38)	C00000947
56751	BARHL1	BarH-like homeobox 1	C00000947
581	BAX, BCL2L4	BCL2-associated X protein	C00000947
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000947
637	BID, FP497	BH3 interacting domain death agonist	C00000947
388962	BOLA3, MMDS2	bolA family member 3	C00000947
79184	BRCC3, BRCC36, C6.1A, CXorf53	BRCA1/BRCA2-containing complex, subunit 3 (EC:3.1.2.15)	C00000947
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00000947
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00000947
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00000947
930	CD19, B4, CVID3	CD19 molecule	C00000947
975	CD81, CVID6, S5.7, TAPA1, TSPAN28	CD81 molecule	C00000947
928	CD9, BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, TSPAN29	CD9 molecule	C00000947
1054	CEBPG, GPE1BP, IG/EBP-1	CCAAT/enhancer binding protein (C/EBP), gamma	C00000947
10978	CLP1, HEAB, hClp1	cleavage and polyadenylation factor I subunit 1 (EC:2.7.1.78)	C00000947
10063	COX17	COX17 cytochrome c oxidase copper chaperone	C00000947
3627	CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1	chemokine (C-X-C motif) ligand 10	C00000947
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00000947
7913	DEK, D6S231E	DEK oncogene	C00000947
1786	DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT	DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37)	C00000947
2130	EWSR1, EWS, bK984G1.4	EWS RNA-binding protein 1	C00000947
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00000947
2323	FLT3LG, FL, FLT3L	fms-related tyrosine kinase 3 ligand	C00000947
2495	FTH1, FHC, FTH, FTHL6, PIG15, PLIF	ferritin, heavy polypeptide 1 (EC:1.16.3.1)	C00000947
2896	GRN, CLN11, GEP, GP88, PCDGF, PEPI, PGRN	granulin	C00000947
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00000947
3054	HCFC1, CFF, HCF-1, HCF1, HFC1, MRX3, VCAF	host cell factor C1 (VP16-accessory protein)	C00000947
3232	HOXD3, HOX1D, HOX4, HOX4A, Hox-4.1	homeobox D3	C00000947
3329	HSPD1, CPN60, GROEL, HLD4, HSP-60, HSP60, HSP65, HuCHA60, SPG13	heat shock 60kDa protein 1 (chaperonin)	C00000947
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00000947
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00000947
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00000947
3559	IL2RA, CD25, IDDM10, IL2R, TCGFR	interleukin 2 receptor, alpha	C00000947
9235	IL32, IL-32alpha, IL-32beta, IL-32delta, IL-32gamma, NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd	interleukin 32	C00000947
3662	IRF4, LSIRF, MUM1, NF-EM5	interferon regulatory factor 4	C00000947
467	ATF3	activating transcription factor 3	C00047901
3689	ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	C00000947
4067	LYN, JTK8, p53Lyn, p56Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (EC:2.7.10.2)	C00000947
5604	MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1	mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)	C00000947
5605	MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2	mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)	C00000947
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00000947
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00000947
4282	MIF, GIF, GLIF, MMIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor) (EC:5.3.3.12 5.3.2.1)	C00000947
64975	MRPL41, BMRP, MRP-L27, MRPL27, RPML27	mitochondrial ribosomal protein L41	C00000947
4493	MT1E, MT1, MTD	metallothionein 1E	C00000947
653361	NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox	neutrophil cytosolic factor 1	C00000947
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00000947
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00000947
4851	NOTCH1, TAN1, hN1	notch 1	C00000947
4869	NPM1, B23, NPM	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	C00000947
5175	PECAM1, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM	platelet/endothelial cell adhesion molecule 1	C00000947
5187	PER1, PER, RIGUI, hPER	period circadian clock 1	C00000947
5327	PLAT, T-PA, TPA	plasminogen activator, tissue (EC:3.4.21.68)	C00000947
5328	PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA	plasminogen activator, urokinase (EC:3.4.21.73)	C00000947
7916	PRRC2A, BAT2, D6S51, D6S51E, G2	proline-rich coiled-coil 2A	C00000947
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00000947
5747	PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK	protein tyrosine kinase 2 (EC:2.7.10.2)	C00000947
5879	RAC1, Rac-1, TC-25, p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	C00000947
5915	RARB, HAP, NR1B2, RRB2	retinoic acid receptor, beta	C00000947
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00000947
6128	RPL6, L6, SHUJUN-2, TAXREB107, TXREB1	ribosomal protein L6	C00000947
6285	S100B, NEF, S100, S100-B, S100beta	S100 calcium binding protein B	C00000947
6286	S100P, MIG9	S100 calcium binding protein P	C00000947
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00000947
7536	SF1, BBP, D11S636, MBBP, ZCCHC25, ZFM1, ZNF162	splicing factor 1	C00000947
6574	SLC20A1, GLVR1, Glvr-1, PIT1, PiT-1	solute carrier family 20 (phosphate transporter), member 1	C00000947
6699	SPRR1B, CORNIFIN, GADD33, SPRR1	small proline-rich protein 1B	C00000947
6772	STAT1, CANDF7, ISGF-3, STAT91	signal transducer and activator of transcription 1, 91kDa	C00000947
6777	STAT5B, STAT5	signal transducer and activator of transcription 5B	C00000947
6778	STAT6, D12S1644, IL-4-STAT, STAT6B, STAT6C	signal transducer and activator of transcription 6, interleukin-4 induced	C00000947
6932	TCF7, TCF-1	transcription factor 7 (T-cell specific, HMG-box)	C00000947
7083	TK1, TK2	thymidine kinase 1, soluble (EC:2.7.1.21)	C00000947
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000947
943	TNFRSF8, CD30, D1S166E, Ki-1	tumor necrosis factor receptor superfamily, member 8	C00000947
7150	TOP1, TOPI	topoisomerase (DNA) I (EC:5.99.1.2)	C00000947
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00000947
2829	XCR1, CCXCR1, GPR5	chemokine (C motif) receptor 1	C00000947
51042	ZNF593, ZT86	zinc finger protein 593	C00000947

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions