Sophora subprostrata

• Index
• Plant Species
• Metabolite list (14)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Sophora subprostrata
Genus	Sophora
Family	Fabaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Sophora
Linked NCBI taxonomy ID	3896
Linked level	genus

Family

Family in NCBI taxonomy	Fabaceae
ID	3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (14)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00006199	Sophoraflavone A					No. 1	No. 15
C00004117	Sophoraflavone B					No. 2	No. 15
C00008196	7,4'-Dihydroxy-6,8-di-C-prenylflavanone	CHEMBL560504				No. 19	No. 14
C00006083	Bayin / 8-beta-D-Glucopyranosyl-4',7-dihydroxyflavone					No. 22	No. 15
C00003749	Lupeol / Lupenol / (+)-Lupenol	CHEMBL289191 CHEMBL459702	C010480	3 / 0 / 0	2 / 6	No. 23	No. 51
C00008251	Sophoranochromene					No. 39
C00002227	Matrine / (+)-Matrine	CHEMBL204860 CHEMBL383443 CHEMBL525227 CHEMBL1396816 CHEMBL1733145 CHEMBL1824581	C034244	5 / 3 / 7	4 / 5	No. 85	No. 3
C00001005	Sophoranone / (-)-Sophoranone					No. 170	No. 14
C00007092	2,4,2'-Trihydroxy-6'',6''-dimethyl-3'-prenylpyrano[2'',3'':4',5']chalcone					No. 186
C00007075	Sophoradochromene					No. 186
C00010188	6'-O-Acetyltrifolirhizin / Trifolirhizin 6'-monoacetate					No. 557	No. 15
C00010186	Trifolirhizin / Sophojaponicin B1 / (-)-Maackiain 3-O-glucoside	CHEMBL454878				No. 557	No. 15
C00007758	Oxymatrine / Ammothamnine / Matrine N-oxide / (+)-Matrine N-oxide / Matrine 1beta-oxide	CHEMBL458337 CHEMBL1358502	C037573	3 / 11 / 6	0 / 4	No. 1211	No. 3
C00007074	Sophoradin					No. 1780

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P11387	DNA topoisomerase 1	Isomerase	C00002227 C00003749	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00007758	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003749	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002227	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00007758	7 / 3
P08047	Transcription factor Sp1	Unclassified protein	C00003749	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00002227	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00007758	4 / 3
O00255	Menin	Unclassified protein	C00002227	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002227	1 / 2

6 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00003749
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00003749
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00002227
4893	NRAS, ALPS4, N-ras, NRAS1, NS6	neuroblastoma RAS viral (v-ras) oncogene homolog	C00002227
7150	TOP1, TOPI	topoisomerase (DNA) I (EC:5.99.1.2)	C00002227
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00002227

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions