Species

KNApSAcK Entry

Organism name Lupinus angustifolius
Genus Lupinus
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Lupinus angustifolius
Linked NCBI taxonomy ID 3871
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (21)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00009523 External link 512 Angustone A
/ 5,7,2',4'-Tetrahydroxy-6,3'-diprenylisoflavone
No. 14 No. 15
C00020646 External link 512 Lupisoflavone
No. 15 No. 15
C00002586 External link 512 Wighteone
/ Erythrinin B
/ 5,7,4'-Trihydroxy-6-prenylisoflavone
CHEMBL393222
2 / 1 / 1 No. 15 No. 15
C00002542 External link 512 Licoisoflavone A
No. 15 No. 15
C00009277 External link 512 Proanthocyanidin A1
CHEMBL286933
CHEMBL81646
CHEMBL450916
13 / 3 / 4 No. 16 No. 19
C00009929 External link 512 Angustone C
/ 5,2',4'-Trihydroxy-3'-prenyl-6'',6''-dimethylpyrano[2'',3'':7,6]isoflavone
No. 18 No. 15
C00009919 External link 512 Angustone B
/ 5,7,2'-Trihydroxy-6-prenyl-6'',6''-dimethylpyrano[2'',3'':4',3']isoflavone
No. 18 No. 15
C00009453 External link 512 2'-Hydroxygenistein
CHEMBL6665
8 / 6 / 5 No. 71 No. 15
C00002225 External link 512 Lupanine
/ (+)-Lupanine
CHEMBL459396
CHEMBL520093
CHEMBL2008918
C008298
No. 85 No. 3
C00007694 External link 512 alpha-Isolupanine
CHEMBL459396
CHEMBL520093
CHEMBL2008918
No. 85 No. 3
C00002228 External link 512 Multiflorine
/ (-)-Multiflorine
CHEMBL517095
No. 424 No. 3
C00007708 External link 512 13alpha-(Caproyloxy)lupanine
No. 712
C00032598 External link 512 13-alpha-Tigloyloxy-lupanine
/ 13alpha-(Tigloyloxy)lupanine
No. 712
C00002208 External link 512 Angustifoline
CHEMBL459206
C101930
No. 1023 No. 3
C00007730 External link 512 Tetrahydrorhombifoline
CHEMBL460224
No. 1023 No. 3
C00025362 External link 512 13alpha-Cinnamoyloxylupanine
No. 1268 No. 3
C00007707 External link 512 13alpha-Benzoyloxylupanine
No. 1268 No. 3
C00013262 External link 512 Pyranochromene
/ [2R-(2alpha,3alpha,8beta,10alpha)]-2-(3,4-Dihydroxyphenyl)-3,4,9,10-tetrahydro-10-methyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-3,5,8-triol
No. 2306
C00008961 External link 512 9,10-Dihydro-8-hydroxy-10-methyl-8H-pyrano[2,3-h]epicatechin
No. 2306
C00000118 External link 512 N-Malonyltryptophan
No. 2986
C00000117 External link 512 Indole-3-acetyl-L-aspartic acid
C026984
No. 2986

Human Protein / Gene in interactions

23 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P06746 DNA polymerase beta Enzyme C00009453 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00009453 1 / 1
P49763 Placenta growth factor Unclassified protein C00009277 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00002586 0 / 1
Q9Y253 DNA polymerase eta Enzyme C00009453 1 / 1
P15692 Vascular endothelial growth factor A Secreted protein C00009277 1 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00009453 0 / 0
P03372 Estrogen receptor NR3A1 C00002586 1 / 1
Q9UNA4 DNA polymerase iota Enzyme C00009453 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00009453 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00009453 4 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00009453 0 / 0
Q05513 Protein kinase C zeta type Iota C00009277 0 / 0
Q04759 Protein kinase C theta type Delta C00009277 0 / 1
Q02156 Protein kinase C epsilon type Eta C00009277 0 / 0
O94806 Serine/threonine-protein kinase D3 Pkd C00009277 0 / 0
P17252 Protein kinase C alpha type Alpha C00009277 0 / 0
Q05655 Protein kinase C delta type Delta C00009277 0 / 0
P05129 Protein kinase C gamma type Alpha C00009277 1 / 1
P05771 Protein kinase C beta type Alpha C00009277 0 / 0
P24723 Protein kinase C eta type Eta C00009277 1 / 0
P41743 Protein kinase C iota type Iota C00009277 0 / 0
Q15139 Serine/threonine-protein kinase D1 Pkd C00009277 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#603933 Microvascular complications of diabetes, susceptibility to, 1; mvcd1 P15692
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#605361 Spinocerebellar ataxia 14; sca14 P05129
#601367 Stroke, ischemic P24723
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (10)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
Q92731 (marker)
H00063 Spinocerebellar ataxia (SCA) P05129 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00018 Gastric cancer P15692 (related)
H00021 Renal cell carcinoma P15692 (marker)
H00408 Type I diabetes mellitus Q04759 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)