Cyperus alopecuroides
Species
KNApSAcK Entry
| Organism name | Cyperus alopecuroides |
|---|---|
| Genus | Cyperus |
| Family | Cyperaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Cyperus alopecuroides |
|---|---|
| Linked NCBI taxonomy ID | 1234173 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Cyperaceae |
|---|---|
| ID | 4609 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Liliopsida |
|---|---|
| ID | 4447 |
Metabolite list (23)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00006229
|
Vicenin 2
/ Apigenin 6,8-di-C-glucoside |
CHEMBL1442950
|
6 / 14 / 8 | No. 1 | No. 15 |
|
||
|
C00001036
|
Diosmetin
/ 4'-Methylluteolin / 5,7,3'-Trihydroxy-4'-methoxyflavone |
CHEMBL90568
|
C039602
|
11 / 12 / 8 | 5 / 0 | No. 3 | No. 15 |
|
|
C00004640
|
Quercetin 3,4'-dimethyl ether
/ 5,7,3'-Trihydroxy-3,4'-dimethoxyflavone / 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3-methoxy-4H-1-benzopyran-4-one |
CHEMBL309263
|
16 / 8 / 2 | No. 3 | No. 15 |
|
||
|
C00004639
|
Quercetin 3,3'-dimethyl ether
/ 5,7,4'-Trihydroxy-3,3'-dimethoxyflavone / 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-methoxy-4H-1-benzopyran-4-one |
CHEMBL511363
|
C060385
|
No. 3 | No. 15 |
|
||
|
C00001078
|
Lutexin
/ Orientin / Luteolin 8-C-beta-D-glucopyranoside / 8-beta-D-Glucopyranosyl-3',4',5,7-tetrahydroxyflavone |
CHEMBL520866
CHEMBL1468796 |
C065886
|
20 / 15 / 14 | No. 22 | No. 15 |
|
|
|
C00003186
|
beta-Selinene
|
C087920
|
No. 151 | No. 38 |
|
|||
|
C00036276
|
(-)-Eudesma-2,4(15)-11-triene
|
No. 151 | No. 38 |
|
||||
|
C00012748
|
Isocyperol
/ (-)-Eudesma-4(14),11-dien-3alpha-ol / [2R-(2alpha,4abeta,7beta,8aalpha)]-Decahydro-4a-methyl-1-methylene-7-(1-methylethenyl)-2-naphthalenol |
CHEMBL489542
|
No. 151 | No. 38 |
|
|||
|
C00003120
|
alpha-Cubebene
|
No. 333 | No. 38 |
|
||||
|
C00003118
|
Copaene
/ alpha-Copaene / (-)-alpha-Copaene |
No. 333 | No. 38 |
|
||||
|
C00008026
|
Sulfuretin
/ Sulphuretin / 6,3',4'-Trihydroxyaurone |
CHEMBL490355
CHEMBL513487 |
C054989
|
42 / 37 / 34 | No. 450 | No. 13 |
|
|
|
C00003110
|
Caryophyllene
/ (E)-Caryophyllene / beta-Caryophyllene / (-)-(E)-Caryophyllene / (E)-beta-Caryophyllene |
CHEMBL445740
CHEMBL448700 |
2 / 3 / 7 | No. 478 | No. 38 |
|
||
|
C00012740
|
Cyperol
|
No. 748 |
|
|||||
|
C00037928
|
trans-Calamenene
|
No. 824 |
|
|||||
|
C00021877
|
Rotundene
|
No. 926 |
|
|||||
|
C00036274
|
(-)-Dolabella-3,7,18-triene
|
CHEMBL1689074
|
No. 1129 |
|
||||
|
C00036277
|
(-)-Eudesma-3,11-dien-5-ol
|
No. 1215 |
|
|||||
|
C00021282
|
Cyperenal
|
No. 1454 |
|
|||||
|
C00021283
|
Cyperene
|
No. 1454 |
|
|||||
|
C00036991
|
Cypera-2,4-diene
/ (-)-Cypera-2,4-diene |
No. 1454 |
|
|||||
|
C00036992
|
Cyprotene
|
No. 1454 |
|
|||||
|
C00007636
|
delta-Cadinene
|
CHEMBL445759
|
No. 1524 | No. 39 |
|
|||
|
C00037114
|
Epoxycyperene
|
No. 2900 |
|
Human Protein / Gene in interactions
75 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001036 C00001078 C00006229 C00008026 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001078 C00006229 C00008026 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001078 C00006229 C00008026 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00001078 C00003110 C00008026 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001078 C00003110 C00008026 | 1 / 2 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00001078 C00006229 C00008026 | 1 / 1 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001078 C00008026 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001078 C00008026 | 4 / 3 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00001078 C00008026 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00001078 C00008026 | 3 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001078 C00008026 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001078 C00008026 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001078 C00008026 | 1 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00001078 C00008026 | 1 / 1 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00006229 C00008026 | 7 / 3 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00008026 | 0 / 1 |
| P39748 | Flap endonuclease 1 | Enzyme | C00008026 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00008026 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00008026 | 2 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00008026 | 4 / 2 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00008026 | 0 / 0 |
| P47901 | Vasopressin V1b receptor | Vasopressin and oxytocin receptor | C00008026 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00008026 | 2 / 3 |
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00008026 | 0 / 0 |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00008026 | 3 / 1 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00001078 | 0 / 0 |
| P11308 | Transcriptional regulator ERG | Unclassified protein | C00008026 | 1 / 2 |
| Q9HBX9 | Relaxin receptor 1 | Relaxin receptor | C00008026 | 0 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00008026 | 0 / 0 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00008026 | 0 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00001036 | 5 / 3 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00001036 | 4 / 4 |
| P04745 | Alpha-amylase 1 | Enzyme | C00001036 | 0 / 0 |
| P10696 | Alkaline phosphatase, placental-like | Enzyme | C00008026 | 0 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001036 | 0 / 0 |
| P08253 | 72 kDa type IV collagenase | M10A | C00008026 | 1 / 3 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00001036 | 2 / 0 |
| Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00001036 | 1 / 1 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00008026 | 1 / 1 |
| Q8WXD0 | Relaxin receptor 2 | Relaxin receptor | C00008026 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00008026 | 0 / 0 |
| O14763 | Tumor necrosis factor receptor superfamily member 10B | Unclassified protein | C00004640 | 1 / 0 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00001036 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001078 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00001036 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00006229 | 6 / 4 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00001036 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00001078 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00001078 | 1 / 1 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00008026 | 0 / 0 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00001036 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001078 | 1 / 1 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00008026 | 0 / 0 |
| O00487 | 26S proteasome non-ATPase regulatory subunit 14 | Enzyme | C00008026 | 0 / 0 |
| Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00008026 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001078 | 0 / 0 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00008026 | 1 / 4 |
| Q13748 | Tubulin alpha-3C/D chain | Structural | C00004640 | 0 / 0 |
| P68366 | Tubulin alpha-4A chain | Structural | C00004640 | 0 / 0 |
| Q9H4B7 | Tubulin beta-1 chain | Structural | C00004640 | 1 / 0 |
| P04350 | Tubulin beta-4A chain | Structural | C00004640 | 2 / 0 |
| Q3ZCM7 | Tubulin beta-8 chain | Structural | C00004640 | 0 / 0 |
| P07437 | Tubulin beta chain | Structural | C00004640 | 0 / 0 |
| Q71U36 | Tubulin alpha-1A chain | Structural | C00004640 | 1 / 1 |
| P68371 | Tubulin beta-4B chain | Structural | C00004640 | 0 / 0 |
| Q13509 | Tubulin beta-3 chain | Structural | C00004640 | 2 / 1 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00008026 | 0 / 0 |
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00008026 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00008026 | 2 / 1 |
| P68363 | Tubulin alpha-1B chain | Unclassified protein | C00004640 | 0 / 0 |
| Q13885 | Tubulin beta-2A chain | Structural | C00004640 | 0 / 0 |
| Q6PEY2 | Tubulin alpha-3E chain | Unclassified protein | C00004640 | 0 / 0 |
| Q9BQE3 | Tubulin alpha-1C chain | Unclassified protein | C00004640 | 0 / 0 |
| Q9BUF5 | Tubulin beta-6 chain | Structural | C00004640 | 0 / 0 |
| Q9BVA1 | Tubulin beta-2B chain | Structural | C00004640 | 1 / 0 |
5 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00001036
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001036
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00001036
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00001036
|
| 1577 | CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 | cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1) |
C00001036
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (65)
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #114500 | Colorectal cancer; crc |
P84022
Q14191 |
| #614039 | Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 |
Q13509
|
| #219050 | Cryptorchidism, unilateral or bilateral |
Q8WXD0
|
| #237500 | Dubin-johnson syndrome; djs |
Q92887
|
| #128101 | Dystonia 4, torsion, autosomal dominant; dyt4 |
P04350
|
| #612219 | Ewing sarcoma; es |
P11308
|
| #600638 | Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a |
Q13509
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #137800 | Glioma susceptibility 1; glm1 |
P37231
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #146300 | Hypophosphatasia, adult |
P05186
|
| #241510 | Hypophosphatasia, childhood |
P05186
|
| #241500 | Hypophosphatasia, infantile |
P05186
|
| #612438 | Leukodystrophy, hypomyelinating, 6; hld6 |
P04350
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #611603 | Lissencephaly 3; lis3 |
Q71U36
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613112 | Macrothrombocytopenia, autosomal dominant, tubb1-related |
Q9H4B7
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P37231
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #167000 | Ovarian cancer |
P38398
|
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #604229 | Peters anomaly |
Q16678
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #610031 | Polymicrogyria, symmetric or asymmetric; pmgysa |
Q9BVA1
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
O14763
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (49)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00213 | Hypophosphatasia |
P05186
(related)
|
| H00025 | Penile cancer |
P08253
(related)
|
| H00028 | Choriocarcinoma |
P08253
(related)
|
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00023 | Testicular cancer |
P10696
(marker)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00024 | Prostate cancer |
P11308
(related)
|
| H00035 | Ewing's sarcoma |
P11308
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00032 | Thyroid cancer |
P37231
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|
| H00027 | Ovarian cancer |
P38398
(related)
|
| H00031 | Breast cancer |
P38398
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00838 | Congenital fibrosis of the extraocular muscles (CFEOM) |
Q13509
(related)
|
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00268 | Lissencephaly (LIS) |
Q71U36
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
Q8WXD0
(related)
|
| H00208 | Hyperbilirubinemia |
Q92887
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|