Organism name | Glaucium corniculatum |
---|---|
Genus | Glaucium |
Family | Papaveraceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Glaucium |
---|---|
Linked NCBI taxonomy ID | 56852 |
Linked level | genus |
Family in NCBI taxonomy | Papaveraceae |
---|---|
ID | 3465 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | eudicotyledons |
---|---|
ID | 71240 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00005548
![]() |
Narcissin
/ Isorhamnetin 3-O-rutinoside |
CHEMBL84174
CHEMBL258394 CHEMBL1711509 CHEMBL2165403 |
C031062
|
7 / 1 / 2 | No. 1 | No. 15 |
![]() |
|
C00001872
![]() |
Isocorydine
/ (+)-Isocorydine / L-(+)-Isocorydine / (S)-(+)-Isocorydine |
CHEMBL489525
CHEMBL1376826 |
14 / 7 / 10 | No. 20 | No. 4 |
![]() |
||
C00001861
![]() |
Glaucine
/ S-(+)-Glaucine / O,O-Dimethylisoboldine |
CHEMBL36536
CHEMBL228082 |
14 / 8 / 6 | No. 20 | No. 4 |
![]() |
||
C00001824
![]() |
Bulbocapnine
/ d-Bulbocapnine |
CHEMBL157912
|
C083807
|
0 / 1 | No. 20 | No. 4 |
![]() |
|
C00027238
![]() |
Thalicmidine
/ Thaliporphine / (+)-Thaliporphine / (S)-O-Methylisoboldine |
CHEMBL1394328
CHEMBL1397308 |
C080702
|
20 / 26 / 56 | No. 20 | No. 4 |
![]() |
|
C00025658
![]() |
/ Eximine / Dicentrine / d-Dicentrine / (+)-Dicentrine / O,N-Dimethyllitseferine |
CHEMBL464748
CHEMBL478754 |
C067342
|
15 / 20 / 16 | No. 20 | No. 4 |
![]() |
|
C00025827
![]() |
Corydine
/ Glaucentrin / (+)-Corydine / Glaucentrine |
CHEMBL489524
CHEMBL2002847 |
C067341
|
1 / 0 / 0 | No. 20 | No. 4 |
![]() |
|
C00025674
![]() |
N-Methylcorydine
/ (+)-N-Methylcorydine |
CHEMBL1617951
|
No. 286 | No. 4 |
![]() |
|||
C00027386
![]() |
Isocorydine-N-oxide
/ (+)-Isocorydine N-oxide |
No. 286 | No. 4 |
![]() |
||||
C00027532
![]() |
Corydine N-oxide
|
No. 286 | No. 4 |
![]() |
||||
C00001906
![]() |
Fumarin
/ Biflorine / Protopine / Fumarine / Corydinine |
CHEMBL453019
|
C009093
|
5 / 5 / 4 | 2 / 0 | No. 820 | No. 4 |
![]() |
C00001799
![]() |
Thalictrimine
/ Allocryptopine / alpha-Fagarine / beta-Homochelidonine / alpha-Allocryptopine |
CHEMBL520043
|
C109505
|
3 / 2 / 3 | 2 / 0 | No. 820 | No. 4 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001861 C00001872 C00001906 C00025658 C00027238 | 0 / 0 |
O75496 | Geminin | Unclassified protein | C00001861 C00001872 C00005548 C00025658 | 0 / 0 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001872 C00001906 C00005548 C00027238 | 0 / 1 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00001799 C00001861 C00005548 C00025658 | 0 / 0 |
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001872 C00001906 C00027238 | 1 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00001861 C00025658 C00027238 | 4 / 3 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00001861 C00001872 C00027238 | 0 / 0 |
Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001861 C00001872 C00027238 | 3 / 3 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001799 C00025658 C00027238 | 1 / 2 |
P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00001872 C00025658 C00025827 | 0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001872 C00001906 C00027238 | 1 / 1 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001861 C00005548 | 0 / 0 |
O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00001872 C00025658 | 1 / 0 |
Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001861 C00025658 | 1 / 0 |
P43351 | DNA repair protein RAD52 homolog | Unclassified protein | C00001861 C00025658 | 0 / 0 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001872 | 0 / 0 |
Q14761 | Protein tyrosine phosphatase receptor type C-associated protein | Enzyme | C00001861 | 0 / 0 |
Q9BQF6 | Sentrin-specific protease 7 | Enzyme | C00001861 | 0 / 0 |
P39748 | Flap endonuclease 1 | Enzyme | C00025658 | 0 / 0 |
P54132 | Bloom syndrome protein | Enzyme | C00027238 | 1 / 2 |
P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00005548 | 0 / 0 |
P07237 | Protein disulfide-isomerase | Enzyme | C00005548 | 0 / 0 |
P06280 | Alpha-galactosidase A | Enzyme | C00027238 | 1 / 1 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00027238 | 0 / 0 |
Q9GZR1 | Sentrin-specific protease 6 | Enzyme | C00001861 | 0 / 0 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001872 | 0 / 1 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00027238 | 2 / 2 |
P42574 | Caspase-3 | C14 | C00001861 | 0 / 0 |
P03372 | Estrogen receptor | NR3A1 | C00005548 | 1 / 1 |
P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00027238 | 0 / 0 |
P55210 | Caspase-7 | C14 | C00027238 | 0 / 0 |
P10828 | Thyroid hormone receptor beta | NR1A2 | C00027238 | 3 / 1 |
P16473 | Thyrotropin receptor | Glycohormone receptor | C00001906 | 3 / 2 |
Q96LD8 | Sentrin-specific protease 8 | Enzyme | C00001861 | 0 / 0 |
O75164 | Lysine-specific demethylase 4A | Enzyme | C00025658 | 0 / 0 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00027238 | 0 / 0 |
P02545 | Prelamin-A/C | Unclassified protein | C00025658 | 11 / 10 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00025658 | 0 / 0 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00027238 | 0 / 0 |
P29466 | Caspase-1 | C14 | C00027238 | 0 / 0 |
P06746 | DNA polymerase beta | Enzyme | C00025658 | 0 / 0 |
O00255 | Menin | Unclassified protein | C00027238 | 2 / 5 |
Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001872 | 0 / 1 |
Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001872 | 1 / 4 |
O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001872 | 0 / 0 |
Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00025658 | 2 / 1 |
P04637 | Cellular tumor antigen p53 | Transcription Factor | C00027238 | 7 / 37 |
Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00001799 | 1 / 1 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001799
C00001906
|
1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00001799
C00001906
|
OMIM | preferred title | UniProt |
---|---|---|
#300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
#202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
#612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
#614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
#210900 | Bloom syndrome; blm |
P54132
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#114500 | Colorectal cancer; crc |
Q14191
|
#119900 | Digital clubbing, isolated congenital |
P15428
|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#133239 | Esophageal cancer |
P04637
|
#615363 | Estrogen resistance; estrr |
P03372
|
#301500 | Fabry disease |
P06280
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#137800 | Glioma susceptibility 1; glm1 |
O75874
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#603373 | Hyperthyroidism, familial gestational |
P16473
|
#609152 | Hyperthyroidism, nonautoimmune |
P16473
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
#151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#211980 | Lung cancer |
P04637
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
#300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
#300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
#260500 | Papilloma of choroid plexus; cpp |
P04637
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
#277700 | Werner syndrome; wrn |
Q14191
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) |
H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
H00006 | Hairy-cell leukemia |
P04637
(related)
|
H00008 | Burkitt lymphoma |
P04637
(related)
|
H00009 | Adult T-cell leukemia |
P04637
(related)
|
H00010 | Multiple myeloma |
P04637
(related)
|
H00013 | Small cell lung cancer |
P04637
(related)
|
H00014 | Non-small cell lung cancer |
P04637
(related)
|
H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
H00018 | Gastric cancer |
P04637
(related)
|
H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
H00022 | Bladder cancer |
P04637
(related)
|
H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
H00027 | Ovarian cancer |
P04637
(related)
|
H00028 | Choriocarcinoma |
P04637
(related)
|
H00029 | Vulvar cancer |
P04637
(related)
|
H00031 | Breast cancer |
P04637
(related)
|
H00032 | Thyroid cancer |
P04637
(related)
|
H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
H00038 | Malignant melanoma |
P04637
(related)
|
H00039 | Basal cell carcinoma |
P04637
(related)
|
H00040 | Squamous cell carcinoma |
P04637
(related)
|
H00041 | Kaposi's sarcoma |
P04637
(related)
|
H00042 | Glioma |
P04637
(related)
P04637 (marker) |
H00044 | Cancer of the anal canal |
P04637
(related)
|
H00046 | Cholangiocarcinoma |
P04637
(related)
|
H00047 | Gallbladder cancer |
P04637
(related)
|
H00048 | Hepatocellular carcinoma |
P04637
(related)
|
H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
H01007 | Choroid plexus papilloma |
P04637
(related)
|
H00021 | Renal cell carcinoma |
P04637
(marker)
|
H00125 | Fabry disease |
P06280
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
H01269 | Congenital hyperthyroidism |
P16473
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00094 | DNA repair defects |
P54132
(related)
|
H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|