Gynerium sagittatum
Species
KNApSAcK Entry
| Organism name | Gynerium sagittatum |
|---|---|
| Genus | Gynerium |
| Family | Poaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Gynerium sagittatum |
|---|---|
| Linked NCBI taxonomy ID | 42053 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Poaceae |
|---|---|
| ID | 4479 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Liliopsida |
|---|---|
| ID | 4447 |
Metabolite list (15)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00004461
|
Tricin 5-glucoside
/ Tricin 5-O-beta-D-glucopyranoside |
CHEMBL1224897
|
No. 2 | No. 15 |
|
|||
|
C00002510
|
Olmelin
/ Pratensol / Biochanin A / Genistein 4'-methyl ether / 5,7-Dihydroxy-4'-methoxyisoflavone |
CHEMBL131921
|
C004541
|
51 / 65 / 83 | 64 / 2 | No. 3 | No. 15 |
|
|
C00013329
|
Tricin
/ 5,7,4'-Trihydroxy-3',5'-dimethoxyflavone / 5,7-Dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL454320
|
C017769
|
No. 3 | No. 15 |
|
||
|
C00000982
|
Naringenin
/ (-)-Naringenin |
CHEMBL9352
CHEMBL32571 |
C005273
|
57 / 46 / 40 | 35 / 10 | No. 25 | No. 14 |
|
|
C00020344
|
7,4'-Dimethoxyflavone
|
CHEMBL16442
|
2 / 1 / 1 | No. 35 | No. 15 |
|
||
|
C00003801
|
Isopratol
/ 4'-Hydroxy-7-methoxyflavone |
CHEMBL1600520
|
14 / 27 / 57 | No. 76 | No. 15 |
|
||
|
C00002524
|
Ferreirin
|
CHEMBL403383
|
No. 106 | No. 14 |
|
|||
|
C00002520
|
Dalbergioidin
/ 5,7,2',4'-Tetrahydroxyisoflavanone |
No. 106 | No. 14 |
|
||||
|
C00034479
|
Dihydrocajanin
|
No. 106 | No. 14 |
|
||||
|
C00009553
|
Dihydrobiochanin A
|
No. 106 | No. 14 |
|
||||
|
C00000152
|
p-Coumaric acid
|
CHEMBL66879
CHEMBL2336752 |
C032171
|
23 / 13 / 18 | 6 / 1 | No. 904 | No. 6 |
|
|
C00034743
|
Z-Cinnamic acid
/ cis-Cinnamic acid |
CHEMBL27246
|
5 / 2 / 2 | No. 904 | No. 6 |
|
||
|
C00000170
|
trans-Cinnamate
/ trans-Cinnamic acid |
CHEMBL27246
|
5 / 2 / 2 | No. 904 | No. 6 |
|
||
|
C00002743
|
Ferulic acid
/ 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid |
CHEMBL32749
|
C004999
|
110 / 52 / 40 | 16 / 6 | No. 1366 | No. 6 |
|
|
C00034423
|
2-Propenoic acid
|
CHEMBL1213529
|
C036658
|
2 / 11 / 10 | No. 6607 |
|
Human Protein / Gene in interactions
178 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P03372 | Estrogen receptor | NR3A1 | C00000152 C00000170 C00000982 C00002510 C00002743 C00034743 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000982 C00002510 C00002743 C00003801 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000982 C00002510 C00002743 C00003801 | 1 / 1 |
| Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00000152 C00000170 C00002743 C00034743 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000982 C00002510 C00002743 C00003801 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000982 C00002510 C00002743 C00003801 | 0 / 1 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000170 C00000982 C00002743 C00034743 | 1 / 1 |
| P15121 | Aldose reductase | Enzyme | C00000152 C00000170 C00000982 C00034743 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002510 C00002743 C00003801 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00000982 C00002510 C00002743 | 0 / 1 |
| O00255 | Menin | Unclassified protein | C00000982 C00002510 C00003801 | 2 / 5 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00000982 C00002510 C00002743 | 0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00002510 C00002743 C00020344 | 1 / 1 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000982 C00002510 C00003801 | 3 / 3 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000152 C00000982 C00002743 | 0 / 3 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000982 C00002510 C00003801 | 1 / 2 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000170 C00000982 C00034743 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00000982 C00002510 C00002743 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00000982 C00002510 C00003801 | 6 / 4 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000152 C00002510 C00002743 | 1 / 8 |
| Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00000982 C00002510 | 1 / 1 |
| Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00000152 C00002743 | 3 / 0 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000152 C00002743 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000152 C00002743 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00000152 C00002743 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00000982 C00002743 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00000982 C00002743 | 1 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00002510 C00003801 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00000982 C00002743 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002510 C00003801 | 2 / 2 |
| P37059 | Estradiol 17-beta-dehydrogenase 2 | Enzyme | C00000982 C00002510 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00002510 C00034423 | 11 / 10 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00000982 C00002743 | 5 / 1 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000152 C00002743 | 1 / 2 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00000982 C00002510 | 2 / 0 |
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00002510 C00020344 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00002510 C00003801 | 4 / 3 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00000152 C00002743 | 0 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000982 C00002743 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00002510 C00002743 | 0 / 0 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00000982 C00002510 | 2 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00000152 C00002743 | 4 / 2 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00000982 C00002510 | 2 / 2 |
| P10275 | Androgen receptor | NR3C4 | C00000982 C00002510 | 3 / 4 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00000152 C00002743 | 0 / 0 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00000152 C00002743 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00000982 C00002510 | 1 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00000152 C00002743 | 1 / 1 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00000982 C00002743 | 0 / 0 |
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00000982 C00002743 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002510 C00003801 | 7 / 37 |
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00000982 C00002743 | 3 / 0 |
| P16152 | Carbonyl reductase [NADPH] 1 | Enzyme | C00000982 C00002510 | 0 / 0 |
| O75828 | Carbonyl reductase [NADPH] 3 | Enzyme | C00000982 C00002510 | 0 / 0 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00000982 C00002510 | 0 / 0 |
| P14061 | Estradiol 17-beta-dehydrogenase 1 | Enzyme | C00000982 C00002510 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00000152 C00002743 | 1 / 2 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002510 C00003801 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00000982 C00002743 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000152 C00002743 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00000152 C00002743 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00002743 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00002743 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00002743 | 1 / 1 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00002743 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00002743 | 1 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00002743 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00002743 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00002743 | 0 / 0 |
| P04278 | Sex hormone-binding globulin | Secreted protein | C00000982 | 0 / 0 |
| P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00000982 | 1 / 1 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00002743 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00002510 | 0 / 0 |
| P42330 | Aldo-keto reductase family 1 member C3 | Enzyme | C00000152 | 0 / 0 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00002743 | 2 / 0 |
| P24864 | G1/S-specific cyclin-E1 | Other cytosolic protein | C00000982 | 0 / 2 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00000982 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00002510 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00002510 | 4 / 2 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00002743 | 0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00002743 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00002743 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00002743 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00002743 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00002743 | 1 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00002743 | 0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00002743 | 0 / 0 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00002743 | 0 / 0 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00000982 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00002743 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00002743 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00002743 | 1 / 0 |
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00002510 | 0 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00002743 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00002743 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00002743 | 1 / 0 |
| P40763 | Signal transducer and activator of transcription 3 | Transcription Factor | C00002510 | 1 / 2 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00002510 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00002743 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00002743 | 0 / 0 |
| Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | Electrochemical transporter | C00000982 | 1 / 0 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00002510 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000982 | 0 / 0 |
| P34969 | 5-hydroxytryptamine receptor 7 | Serotonin receptor | C00002743 | 0 / 0 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00002743 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00002743 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00002743 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00002743 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00002743 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00002743 | 2 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00000982 | 5 / 3 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00002743 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00002743 | 1 / 0 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00000982 | 4 / 4 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00002743 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00002743 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00002743 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00002743 | 0 / 0 |
| P04745 | Alpha-amylase 1 | Enzyme | C00000982 | 0 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00002743 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00002743 | 1 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00002743 | 1 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00002743 | 2 / 1 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00002743 | 0 / 0 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00002743 | 0 / 0 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00002743 | 0 / 1 |
| P05091 | Aldehyde dehydrogenase, mitochondrial | Oxidoreductase | C00002510 | 1 / 1 |
| P62158 | Calmodulin | Unclassified protein | C00000982 | 1 / 0 |
| Q04828 | Aldo-keto reductase family 1 member C1 | Enzyme | C00000152 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00002743 | 2 / 2 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00002510 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00002510 | 0 / 0 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00000982 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00000982 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00002743 | 0 / 0 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00002743 | 1 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00002743 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00002743 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00002743 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00002743 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00002743 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00002743 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00002743 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00002743 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00002743 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00002743 | 0 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00002743 | 0 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00002743 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000982 | 0 / 0 |
| P52895 | Aldo-keto reductase family 1 member C2 | Enzyme | C00000152 | 1 / 0 |
| P08246 | Neutrophil elastase | S1A | C00002743 | 2 / 1 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00002743 | 2 / 2 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00002743 | 0 / 0 |
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00000152 | 0 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00002743 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00002743 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00002743 | 0 / 0 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00000982 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00002743 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00002743 | 1 / 1 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00000982 | 0 / 0 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00002743 | 0 / 1 |
| Q04760 | Lactoylglutathione lyase | Enzyme | C00000982 | 0 / 0 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00002743 | 0 / 0 |
| P49888 | Estrogen sulfotransferase | Enzyme | C00000982 | 0 / 0 |
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00000982 | 0 / 0 |
| Q12794 | Hyaluronidase-1 | Enzyme | C00002743 | 1 / 2 |
| Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | Electrochemical transporter | C00000982 | 1 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00002510 | 0 / 0 |
| P42224 | Signal transducer and activator of transcription 1-alpha/beta | Unclassified protein | C00002510 | 3 / 3 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00034423 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000982 | 1 / 1 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00002510 | 4 / 1 |
| P17516 | Aldo-keto reductase family 1 member C4 | Enzyme | C00000152 | 1 / 0 |
| Q00653 | Nuclear factor NF-kappa-B p100 subunit | Transcription Factor | C00002510 | 0 / 0 |
| Q04206 | Transcription factor p65 | Transcription Factor | C00002510 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00002510 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00002510 | 1 / 1 |
95 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000152
C00000982
C00002510
C00002743
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00000152
C00000982
C00002510
C00002743
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00000982
C00002510
C00002743
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00000982
C00002510
C00002743
|
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00000982
C00002510
C00002743
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00000982
C00002510
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00000982
C00002510
|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00000982
C00002510
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00000152
C00002743
|
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00000982
C00002510
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00000982
C00002510
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00002510
C00002743
|
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00000982
C00002510
|
| 1588 | CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM | cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000982
C00002510
|
| 7299 | TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 | tyrosinase (EC:1.14.18.1) |
C00000152
C00002743
|
| 6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00000152
C00000982
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00000982
C00002510
|
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00000982
C00002510
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00000982
C00002510
|
| 5925 | RB1, OSRC, RB, p105-Rb, pRb, pp110 | retinoblastoma 1 |
C00002743
|
| 59084 | ENPP5 | ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) |
C00002510
|
| 2060 | EPS15, AF-1P, AF1P, MLLT5 | epidermal growth factor receptor pathway substrate 15 |
C00002510
|
| 51071 | DERA, DEOC | deoxyribose-phosphate aldolase (putative) (EC:4.1.2.4) |
C00002510
|
| 1594 | CYP27B1, CP2B, CYP1, CYP1alpha, CYP27B, P450c1, PDDR, VDD1, VDDR, VDDRI, VDR | cytochrome P450, family 27, subfamily B, polypeptide 1 (EC:1.14.13.13) |
C00002510
|
| 2101 | ESRRA, ERR1, ERRa, ERRalpha, ESRL1, NR3B1 | estrogen-related receptor alpha |
C00002510
|
| 2103 | ESRRB, DFNB35, ERR2, ERRb, ESRL2, NR3B2 | estrogen-related receptor beta |
C00002510
|
| 2104 | ESRRG, ERR3, ERRgamma, NR3B3 | estrogen-related receptor gamma |
C00002510
|
| 2091 | FBL, FIB, FLRN, RNU3IP1 | fibrillarin |
C00002510
|
| 2348 | FOLR1, FBP, FOLR | folate receptor 1 (adult) |
C00002510
|
| 2760 | GM2A, GM2-AP, SAP-3 | GM2 ganglioside activator |
C00002510
|
| 2773 | GNAI3, 87U6, ARCND1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 |
C00002510
|
| 2876 | GPX1, GPXD, GSHPX1 | glutathione peroxidase 1 (EC:1.11.1.9) |
C00002510
|
| 9766 | KIAA0247 |
C00002510
|
|
| 753 | LDLRAD4, C18orf1 | low density lipoprotein receptor class A domain containing 4 |
C00002510
|
| 56925 | LXN, ECI, TCI | latexin |
C00002510
|
| 4323 | MMP14, MMP-14, MMP-X1, MT-MMP, MT-MMP_1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS | matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80) |
C00002510
|
| 4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) |
C00002510
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00002510
|
| 4502 | MT2A, MT2 | metallothionein 2A |
C00002510
|
| 4698 | NDUFA5, B13, CI-13KD-B, CI-13kB, NUFM, UQOR13 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (EC:1.6.5.3 1.6.99.3) |
C00002510
|
| 4841 | NONO, NMT55, NRB54, P54, P54NRB | non-POU domain containing, octamer-binding |
C00002510
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00002510
|
| 5204 | PFDN5, MM-1, MM1, PFD5 | prefoldin subunit 5 |
C00002510
|
| 5241 | PGR, NR3C3, PR | progesterone receptor |
C00002510
|
| 5329 | PLAUR, CD87, U-PAR, UPAR, URKR | plasminogen activator, urokinase receptor |
C00002510
|
| 10957 | PNRC1, B4-2, PNAS-145, PROL2, PRR2 | proline-rich nuclear receptor coactivator 1 |
C00002510
|
| 55684 | RABL6, C9orf86, PARF, RBEL1, pp8875 | RAB, member RAS oncogene family-like 6 |
C00002510
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002510
|
| 55183 | RIF1 | RAP1 interacting factor homolog (yeast) |
C00002510
|
| 285367 | RPUSD3 | RNA pseudouridylate synthase domain containing 3 |
C00002510
|
| 6455 | SH3GL1, CNSA1, EEN, SH3D2B, SH3P8 | SH3-domain GRB2-like 1 |
C00002510
|
| 5250 | SLC25A3, PHC, PTP | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 |
C00002510
|
| 6426 | SRSF1, ASF, SF2, SF2p33, SFRS1, SRp30a | serine/arginine-rich splicing factor 1 |
C00002510
|
| 84222 | TMEM191A, TMEM191AP | transmembrane protein 191A (pseudogene) |
C00002510
|
| 27242 | TNFRSF21, BM-018, CD358, DR6 | tumor necrosis factor receptor superfamily, member 21 |
C00002510
|
| 203068 | TUBB, M40, OK/SW-cl.56, TUBB1, TUBB5 | tubulin, beta class I |
C00002510
|
| 7322 | UBE2D2, E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH5B | ubiquitin-conjugating enzyme E2D 2 (EC:6.3.2.19) |
C00002510
|
| 1152 | CKB, B-CK, CKBB | creatine kinase, brain (EC:2.7.3.2) |
C00002510
|
| 1000 | CDH2, CD325, CDHN, CDw325, NCAD | cadherin 2, type 1, N-cadherin (neuronal) |
C00002510
|
| 9577 | BRE, BRCC4, BRCC45 | brain and reproductive organ-expressed (TNFRSF1A modulator) |
C00002510
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00002510
|
| 84159 | ARID5B, DESRT, MRF-2, MRF2 | AT rich interactive domain 5B (MRF1-like) |
C00002510
|
| 54663 | WDR74 | WD repeat domain 74 |
C00002510
|
| 80014 | WWC2, BOMB | WW and C2 domain containing 2 |
C00002510
|
| 23621 | BACE1, ASP2, BACE, HSPC104 | beta-site APP-cleaving enzyme 1 (EC:3.4.23.46) |
C00002743
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00002743
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00002743
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00002743
|
| 5742 | PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00002743
|
| 501 | ALDH7A1, ATQ1, EPD, PDE | aldehyde dehydrogenase 7 family, member A1 (EC:1.2.1.3 1.2.1.8 1.2.1.31) |
C00002510
|
| 1983 | EIF5, EIF-5, EIF-5A | eukaryotic translation initiation factor 5 |
C00002510
|
| 6319 | SCD, FADS5, MSTP008, SCD1, SCDOS | stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) |
C00002743
|
| 375790 | AGRN | agrin |
C00002510
|
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) |
C00002743
|
| 10257 | ABCC4, EST170205, MOAT-B, MOATB, MRP4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
C00000982
|
| 10057 | ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
C00000982
|
| 1645 | AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB | aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) |
C00000982
|
| 8644 | AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS | aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) |
C00000982
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00000982
|
| 249 | ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP | alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) |
C00000982
|
| 405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator |
C00000982
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00000982
|
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00000982
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00000982
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00000982
|
| 3757 | KCNH2, ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1 | potassium voltage-gated channel, subfamily H (eag-related), member 2 |
C00000982
|
| 5444 | PON1, ESA, MVCD5, PON | paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) |
C00000982
|
| 6566 | SLC16A1, HHF7, MCT, MCT1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
C00000982
|
| 6513 | SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED | solute carrier family 2 (facilitated glucose transporter), member 1 |
C00000982
|
| 1244 | ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
C00002510
|
| 6818 | SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) |
C00000982
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00000982
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00000982
|
| 7366 | UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 | UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) |
C00000982
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00000152
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (123)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #614279 | 46,xy sex reversal 8; srxy8 |
P17516
P52895 |
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #610251 | Alcohol sensitivity, acute |
P05091
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #600807 | Asthma, susceptibility to |
Q13093
|
| #209950 | Atypical mycobacteriosis, familial |
P42224
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #300615 | Brunner syndrome |
P21397
|
| #614162 | Candidiasis, familial, 7; candf7 |
P42224
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P18054
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #237500 | Dubin-johnson syndrome; djs |
Q92887
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
P18054 |
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #137800 | Glioma susceptibility 1; glm1 |
P04626
P37231 |
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #147060 | Hyper-ige recurrent infection syndrome, autosomal dominant |
P40763
|
| #237450 | Hyperbilirubinemia, rotor type; hblrr |
Q9NPD5
Q9Y6L6 |
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #147050 | Ige responsiveness, atopic; iger |
Q13093
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #601626 | Leukemia, acute myeloid; aml |
P36888
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 P04637 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #601492 | Mucopolysaccharidosis, type ix; mps9 |
Q12794
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #613796 | Mycobacterial and viral infections, susceptibility to, autosomal recessive |
P42224
|
| #159900 | Myoclonic dystonia |
P14416
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P32245
P37231 |
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
P38398 |
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #604229 | Peters anomaly |
Q16678
|
| #172700 | Pick disease of brain |
P10636
|
| #614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #614916 | Ventricular tachycardia, catecholaminergic polymorphic, 4; cpvt4 |
P62158
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278300 | Xanthinuria, type i |
P47989
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (107)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) P40763 (related) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) P24864 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) P24864 (related) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
P11511 (related) |
| H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
| H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) P38398 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) P38398 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P35354 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P14780 (related) P35354 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
P14679 (marker) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H01071 | Acute alcohol sensitivity |
P05091
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
Q92887 (related) |
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00003 | Acute myeloid leukemia (AML) |
P36888
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00107 | Other well-defined immunodeficiency syndromes |
P40763
(related)
|
| H00089 | IFN-gamma/IL-12 axis |
P42224
(related)
|
| H00363 | Candidiasis |
P42224
(related)
|
| H01109 | Chronic mucocutaneous candidiasis (CMC) |
P42224
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00133 | Mucopolysaccharidosis type IX (MPS9) |
Q12794
(related)
|
| H00421 | Mucopolysaccharidosis (MPS) |
Q12794
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
Diseases related to CTD interactions
17 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D008106 | Liver Cirrhosis, Experimental |
C00002743
C00000982 |
| D008545 | Melanoma |
C00002743
C00000152 |
| D000647 | Amnesia |
C00000982
|
| D002252 | Carbon Tetrachloride Poisoning |
C00002743
|
| D007249 | Inflammation |
C00002743
|
| D005909 | Glioblastoma |
C00002510
|
| D011471 | Prostatic Neoplasms |
C00002510
|
| D009203 | Myocardial Infarction |
C00002743
|
| D050197 | Atherosclerosis |
C00002743
|
| D001932 | Brain Neoplasms |
C00000982
|
| D009202 | Cardiomyopathies |
C00000982
|
| D056486 | Drug-Induced Liver Injury |
C00000982
|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
C00000982
|
| D007674 | Kidney Diseases |
C00000982
|
| D008107 | Liver Diseases |
C00000982
|
| D009369 | Neoplasms |
C00000982
|
| D009374 | Neoplasms, Experimental |
C00000982
|