| Organism name | Corydalis claviculata |
|---|---|
| Genus | Corydalis |
| Family | Fumariaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Corydalis |
|---|---|
| Linked NCBI taxonomy ID | 3463 |
| Linked level | genus |
| Family in NCBI taxonomy | Papaveraceae |
|---|---|
| ID | 3465 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00026087
|
Cheilanthifoline
/ (-)-Cheilanthifoline |
No. 37 | No. 4 |
|
||||
|
C00026095
|
Stylopine
/ (-)-Stylopine / l-Tetrahydrocoptisine / (-)-Tetrahydrocoptisine |
CHEMBL1922602
|
No. 37 | No. 4 |
|
|||
|
C00028782
|
Oxocularicine
|
No. 74 |
|
|||||
|
C00024773
|
Oxocularine
|
CHEMBL510574
|
No. 74 |
|
||||
|
C00024647
|
Dihydrosanguinarine
|
CHEMBL465678
|
No. 195 | No. 4 |
|
|||
|
C00028907
|
Ribasine
|
No. 233 | No. 4 |
|
||||
|
C00028730
|
Norribasine
/ N-Demethylribasine |
No. 233 | No. 4 |
|
||||
|
C00025924
|
Juziphine
/ Yuziphine / (+)-Juziphine |
CHEMBL462956
|
No. 253 | No. 4 |
|
|||
|
C00001910
|
Reticuline
/ (+)-Reticuline |
CHEMBL235212
CHEMBL401501 CHEMBL464734 |
C003298
|
1 / 0 / 0 | No. 345 | No. 4 |
|
|
|
C00024764
|
Sarcocapnidine
/ (+)-Sarcocapnidine |
CHEMBL510777
|
No. 361 |
|
||||
|
C00024760
|
Limalongine
/ (+)-Limousamine |
No. 361 |
|
|||||
|
C00024761
|
Norcularicine
/ (+)-Norcularicine |
No. 361 |
|
|||||
|
C00024762
|
(+)-Norcularidine
|
No. 361 |
|
|||||
|
C00024763
|
(+)-O-Methylcularicine
|
No. 361 |
|
|||||
|
C00024759
|
Enneaphylline
/ (+)-Enneaphylline |
No. 361 |
|
|||||
|
C00001840
|
Cularidine
|
CHEMBL455633
|
C070411
|
No. 361 |
|
|||
|
C00024758
|
Claviculine
/ (+)-Claviculine |
CHEMBL452512
|
No. 361 |
|
||||
|
C00024755
|
Culacorine
/ (+)-Breoganine |
CHEMBL452510
|
No. 361 |
|
||||
|
C00028086
|
Corycularicine
|
No. 361 |
|
|||||
|
C00001842
|
Cularine
/ (+)-Cularine |
C064577
|
No. 361 |
|
||||
|
C00001839
|
Cularicine
|
No. 361 |
|
|||||
|
C00026002
|
Pallidine
/ (-)-Pallidine / (-)-Isosalutaridine |
No. 426 | No. 4 |
|
||||
|
C00027787
|
8-Oxycoptisine
|
No. 439 |
|
|||||
|
C00001862
|
Glaziovine
/ L-Glaziovine / N-Methylcrotsparine / L-(-)-N-Methylcrotsparine |
CHEMBL1980854
|
C007847
|
No. 688 |
|
|||
|
C00001906
|
Fumarin
/ Biflorine / Protopine / Fumarine / Corydinine |
CHEMBL453019
|
C009093
|
5 / 5 / 4 | 2 / 0 | No. 820 | No. 4 |
|
|
C00024777
|
Secocularidine
|
CHEMBL508081
|
No. 1618 |
|
||||
|
C00028096
|
Crassifoline methine
|
No. 1618 |
|
|||||
|
C00028456
|
Leonticine
|
No. 1618 |
|
|||||
|
C00024770
|
Norsecocularine
|
No. 1618 |
|
|||||
|
C00024771
|
Noyaine
|
No. 1978 |
|
|||||
|
C00028973
|
Sauvagnine
|
No. 3013 |
|
|||||
|
C00028095
|
Crassifolazonine
|
No. 4053 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001906 | 1 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001906 | 3 / 2 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00001910 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001906 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001906 | 0 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001906 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001906
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00001906
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|