| Organism name | Ocotea vellosiana |
|---|---|
| Genus | Ocotea |
| Family | Lauraceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Ocotea |
|---|---|
| Linked NCBI taxonomy ID | 63801 |
| Linked level | genus |
| Family in NCBI taxonomy | Lauraceae |
|---|---|
| ID | 3433 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | Magnoliophyta |
|---|---|
| ID | 3398 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00001861
|
Glaucine
/ S-(+)-Glaucine / O,O-Dimethylisoboldine |
CHEMBL36536
CHEMBL228082 |
14 / 8 / 6 | No. 20 | No. 4 |
|
||
|
C00001872
|
Isocorydine
/ (+)-Isocorydine / L-(+)-Isocorydine / (S)-(+)-Isocorydine |
CHEMBL489525
CHEMBL1376826 |
14 / 7 / 10 | No. 20 | No. 4 |
|
||
|
C00027447
|
Ocotein
/ Ocoteine / Thalicmin / Thalicmine |
CHEMBL443099
|
No. 20 | No. 4 |
|
|||
|
C00027228
|
Nordicentrine
/ (+)-Nordicentrine |
CHEMBL518744
|
C084697
|
No. 20 | No. 4 |
|
||
|
C00026016
|
Predicentrine
/ (+)-Predicentrine |
CHEMBL404136
|
No. 20 | No. 4 |
|
|||
|
C00025827
|
Corydine
/ Glaucentrin / (+)-Corydine / Glaucentrine |
CHEMBL489524
CHEMBL2002847 |
C067341
|
1 / 0 / 0 | No. 20 | No. 4 |
|
|
|
C00025658
|
/ Eximine / Dicentrine / d-Dicentrine / (+)-Dicentrine / O,N-Dimethyllitseferine |
CHEMBL464748
CHEMBL478754 |
C067342
|
15 / 20 / 16 | No. 20 | No. 4 |
|
|
|
C00005864
|
Kaempferol 3-(4''-p-coumarylrhamnoside)
|
No. 30 | No. 15 |
|
||||
|
C00005869
|
Kaempferol 3-(3'',4''-di-p-coumarylrhamnoside)
|
No. 231 |
|
|||||
|
C00005868
|
Kaempferol 3-(2'',4''-di-(E)-p-coumarylrhamnoside)
|
CHEMBL1642586
CHEMBL1797052 |
1 / 1 / 1 | No. 231 |
|
|||
|
C00001910
|
Reticuline
/ (+)-Reticuline |
CHEMBL235212
CHEMBL401501 CHEMBL464734 |
C003298
|
1 / 0 / 0 | No. 345 | No. 4 |
|
|
|
C00027558
|
Leucoxylonine
|
No. 3042 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| O75496 | Geminin | Unclassified protein | C00001861 C00001872 C00025658 | 0 / 0 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00001872 C00025658 C00025827 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001861 C00001872 C00025658 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001861 C00025658 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001861 C00025658 | 4 / 3 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00001872 C00025658 | 1 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001861 C00001872 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001861 C00025658 | 1 / 0 |
| P43351 | DNA repair protein RAD52 homolog | Unclassified protein | C00001861 C00025658 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001861 C00001872 | 3 / 3 |
| Q14761 | Protein tyrosine phosphatase receptor type C-associated protein | Enzyme | C00001861 | 0 / 0 |
| Q9GZR1 | Sentrin-specific protease 6 | Enzyme | C00001861 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00025658 | 0 / 0 |
| Q9BQF6 | Sentrin-specific protease 7 | Enzyme | C00001861 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00025658 | 1 / 2 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001872 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001872 | 0 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001861 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00001910 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001872 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001872 | 0 / 1 |
| P98170 | E3 ubiquitin-protein ligase XIAP | Other cytosolic protein | C00005868 | 1 / 1 |
| P42574 | Caspase-3 | C14 | C00001861 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00025658 | 0 / 0 |
| Q96LD8 | Sentrin-specific protease 8 | Enzyme | C00001861 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00025658 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00025658 | 11 / 10 |
| P06746 | DNA polymerase beta | Enzyme | C00025658 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001872 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001872 | 1 / 4 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001872 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00025658 | 2 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001872 | 1 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
Q14191
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #300635 | Lymphoproliferative syndrome, x-linked, 2; xlp2 |
P98170
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00107 | Other well-defined immunodeficiency syndromes |
P98170
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|