Thuja occidentalis

• Index
• Plant Species
• Natural Activity
• Metabolite list (15)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Thuja occidentalis
Genus	Thuja
Family	Cupressaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Thuja occidentalis
Linked NCBI taxonomy ID	3317
Linked level	species

Family

Family in NCBI taxonomy	Cupressaceae
ID	3367

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Spermatophyta
ID	58024

Natural Activity

List (26)

Species	Activity
Thuja occidentalis L.	Abortifacient
Thuja occidentalis L.	Analgesic
Thuja occidentalis L.	Anaphrodisiac
Thuja occidentalis L.	Antibacterial
Thuja occidentalis L.	Antiseptic
Thuja occidentalis L.	Convulsant
Thuja occidentalis L.	Couterirritant
Thuja occidentalis L.	Cytotoxic
Thuja occidentalis L.	Depurative
Thuja occidentalis L.	Diaphoretic
Thuja occidentalis L.	Diuretic
Thuja occidentalis L.	Emmenagogue
Thuja occidentalis L.	Expectorant
Thuja occidentalis L.	Fungicide
Thuja occidentalis L.	Hypotensive
Thuja occidentalis L.	Immnostimulant
Thuja occidentalis L.	Insectifuge
Thuja occidentalis L.	Lactagogue
Thuja occidentalis L.	Phagocytotic
Thuja occidentalis L.	Secretagogue
Thuja occidentalis L.	Spasmogenic
Thuja occidentalis L.	Stimulant
Thuja occidentalis L.	Tonic
Thuja occidentalis L.	toxic
Thuja occidentalis L.	Uterotonic
Thuja occidentalis L.	Vermifuge

Metabolite list (15)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00003064	Thujone
C00004453	Tricetin 3'-glucoside	CHEMBL1221723				No. 2	No. 15
C00007190	(+)-Pinoresinol	CHEMBL267963 CHEMBL487611 CHEMBL460862	C103298	7 / 5 / 6		No. 38	No. 21
C00021722	alpha-Funebrene					No. 149	No. 38
C00002598	Yatein / (-)-Yatein / (-)-Deoxypodorhizone / Dihydroanhydropodorhizol	CHEMBL345590 CHEMBL471067 CHEMBL2021357	C452802	2 / 1 / 1		No. 223	No. 21
C00007203	(+)-Wikstromol / (+)-Nortrachelogenin	CHEMBL453799 CHEMBL1483370		3 / 2 / 2		No. 223	No. 21
C00000606	(-)-Matairesinol	CHEMBL425148	C068935	1 / 0 / 0		No. 223	No. 21
C00000604	(-)-Secoisolariciresinol	CHEMBL368347	C060283	2 / 1 / 1	1 / 0	No. 282	No. 21
C00002597	Deoxypodophyllotoxin / (-)-Deoxypodophyllotoxin	CHEMBL63970 CHEMBL149525 CHEMBL152144 CHEMBL255919 CHEMBL519603 CHEMBL476679 CHEMBL1736070		7 / 4 / 2		No. 427	No. 21
C00000165	gamma-Eudesmol	CHEMBL477900				No. 613	No. 38
C00011011	alpha-Thujaplicin / 2-Hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one	CHEMBL1275969				No. 1304	No. 35
C00011052	(-)-alpha-Thujene					No. 1343	No. 35
C00011027	(-)-Fenchone					No. 1921	No. 35
C00013242	Occidol / (R)-1,2,3,4-Tetrahydro-a,a,5,8-tetramethyl-2-naphthalenemethanol					No. 2030
C00012732	Occidentalol / (+)-Occidentalol / 10alpha-Eudesma-1,3-dien-11-ol / [2R-(2alpha,4abeta,8abeta)]-1,2,3,4,4a,8a-hexahydro-alpha,alpha,4a,8-tetramethyl-2-naphthalenemethanol					No. 4166

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000604 C00002597 C00002598	0 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000604 C00002598	1 / 0
Q99700	Ataxin-2	Unclassified protein	C00002597 C00007203	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00007190 C00007203	0 / 0
O75496	Geminin	Unclassified protein	C00002597	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00007190	0 / 0
P04278	Sex hormone-binding globulin	Secreted protein	C00000606	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00002597	2 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00007203	1 / 1
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00002597	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00007190	5 / 3
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00007190	0 / 3
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00007190	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002597	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00007190	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002597	1 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00007190	0 / 0

1 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00000604

Related Diseases

Diseases related to proteins in ChEMBL interactions