Dorstenia poinsettifolia

• Index
• Plant Species
• Metabolite list (10)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Dorstenia poinsettifolia
Genus	Dorstenia
Family	Moraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Dorstenia
Linked NCBI taxonomy ID	106722
Linked level	genus

Family

Family in NCBI taxonomy	Moraceae
ID	3487

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (10)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00004090	Licoflavone C / 8-Prenylapigenin / 5,7,4'-Trihydroxy-8-prenylflavone / 5,7-Dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one	CHEMBL371562		1 / 0 / 0		No. 15	No. 15
C00003776	Lutein / (all-E)-Lutein / all-trans-(+)-Xanthophyll / (3R,3'R,6'R)-beta,epsilon-Carotene-3,3'-diol	CHEMBL173929 CHEMBL172477 CHEMBL1559643 CHEMBL1979448	D014975	4 / 2 / 3	7 / 2	No. 26	No. 59
C00011161	Poinsettifolin A / 2-(3,4-Dihydroxyphenyl)-3,5-dihydroxy-8-methyl-6-(3-methyl-2-butenyl)-8-(4-methyl-3-pentenyl)-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one					No. 44
C00011163	Butyrospermol / (-)-Butyrospermol	CHEMBL1835433				No. 119	No. 51
C00008399	4'-Hydroxyisolonchocarpin					No. 127	No. 14
C00014224	Dorspoinsettifolin / 4'-Methoxy-6'',6''-dimethyldihydropyrano[2'',3'':7,8]flavanone					No. 127	No. 14
C00007061	Isobavachromene / 4-Hydroxylonchocarpin	CHEMBL362378		1 / 0 / 0		No. 130
C00036580	4-Hydroxylonchocarpin	CHEMBL362378		1 / 0 / 0		No. 130
C00002381	Corylifolinin / Isobavachalcone / 2',4,4'-Trihydroxy-3'-(3-methyl-2-butenyl)chalcone	CHEMBL253467	C468754	8 / 22 / 21		No. 133	No. 13
C00011162	Poinsettifolin B					No. 186

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P11926	Ornithine decarboxylase	Lyase	C00007061 C00036580	0 / 0
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00002381	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00003776	2 / 3
P21802	Fibroblast growth factor receptor 2	TK tyrosine-protein kinase TLK subfamily	C00002381	9 / 3
O75496	Geminin	Unclassified protein	C00003776	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00003776	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00002381	2 / 2
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00002381	1 / 8
P35968	Vascular endothelial growth factor receptor 2	Vegfr	C00002381	1 / 0
P08581	Hepatocyte growth factor receptor	TK tyrosine-protein kinase MET subfamily	C00002381	2 / 3
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00004090	0 / 0
P11362	Fibroblast growth factor receptor 1	Fgfr	C00002381	4 / 5
P10721	Mast/stem cell growth factor receptor Kit	Pdgfr	C00002381	4 / 3
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00003776	0 / 0

7 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
581	BAX, BCL2L4	BCL2-associated X protein	C00003776
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00003776
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00003776
847	CAT	catalase (EC:1.11.1.6)	C00003776
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00003776
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00003776
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00003776

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions