PCIDB

Curculigo capitulata

Species

KNApSAcK Entry

Organism name Curculigo capitulata
Genus Curculigo
Family Hypoxidaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Molineria capitulata
Linked NCBI taxonomy ID 72645
Linked level species

Family

Family in NCBI taxonomy Hypoxidaceae
ID 4674

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (9)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00040931 External link 512 Curlignan
/ (+)-Curlignan
No. 215 No. 23
C00019308 External link 512 Doursterol
/ Daucosterin
/ 3-O-beta-D-Glucopyranosyl sitosterol
/ beta-Sitosterol 3-O-beta-D-glucopyranoside
CHEMBL197711
CHEMBL506678
CHEMBL2304043
C011015
5 / 4 / 2 0 / 3 No. 520
C00002683 External link 512 Vanillin
CHEMBL13883
18 / 8 / 9 No. 1003
C00040794 External link 512 2,6-Dimethoxy-benzoic acid
CHEMBL488609
C472445
6 / 2 / 4 No. 1073
C00032950 External link 512 Ethyl protocatechuate
/ Ethyl 3,4-dihydroxybenzoate
CHEMBL486216
C018063
7 / 3 / 5 No. 1722
C00002657 External link 512 p-Formylphenol
/ 4-Hydroxybenzaldehyde
/ p-Hydroxybenzaldehyde
CHEMBL14193
C011483
3 / 2 / 2 No. 2076
C00049057 External link 512 (1S,2R)-O-Methylnyasicoside
CHEMBL485804
No. 2727
C00049140 External link 512 Curcapital
No. 3529
C00040791 External link 512 2,4-Dichloro-5-methoxy-3-methylphenol
No. 3671

Human Protein / Gene in interactions

31 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P43166 Carbonic anhydrase 7 Lyase C00032950 C00040794 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00032950 C00040794 0 / 1
P80404 4-aminobutyrate aminotransferase, mitochondrial Transferase C00002657 C00002683 1 / 1
P00915 Carbonic anhydrase 1 Lyase C00032950 C00040794 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00032950 C00040794 1 / 2
Q9ULX7 Carbonic anhydrase 14 Lyase C00032950 C00040794 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00032950 C00040794 1 / 2
P51649 Succinate-semialdehyde dehydrogenase, mitochondrial Oxidoreductase C00002657 C00002683 1 / 1
P14902 Indoleamine 2,3-dioxygenase 1 Enzyme C00002657 0 / 0
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00002683 0 / 0
Q9GZT9 Egl nine homolog 1 Enzyme C00032950 1 / 1
Q9HAW7 UDP-glucuronosyltransferase 1-7 Enzyme C00002683 0 / 0
P08047 Transcription factor Sp1 Unclassified protein C00019308 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002683 0 / 0
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00019308 0 / 0
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00002683 0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme C00002683 0 / 0
P06746 DNA polymerase beta Enzyme C00019308 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00019308 0 / 0
O00519 Fatty-acid amide hydrolase 1 Enzyme C00002683 0 / 0
P00734 Prothrombin S1A C00019308 4 / 2
P78527 DNA-dependent protein kinase catalytic subunit Atypical serine/threonine protein kinase PIKK subfamily C00002683 0 / 0
Q96RI1 Bile acid receptor NR1H4 C00002683 0 / 0
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00002683 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002683 2 / 2
Q9Y4X1 UDP-glucuronosyltransferase 2A1 Enzyme C00002683 0 / 0
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00002683 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002683 0 / 0
P10275 Androgen receptor NR3C4 C00002683 3 / 4
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00002683 1 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002683 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#119900 Digital clubbing, isolated congenital P15428
#609820 Erythrocytosis, familial, 3; ecyt3 Q9GZT9
#613163 Gaba-transaminase deficiency P80404
#143860 Hyperchlorhidrosis, isolated O43570
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601367 Stroke, ischemic P00734
#271980 Succinic semialdehyde dehydrogenase deficiency; ssadhd P51649
#188050 Thrombophilia due to thrombin defect; thph1 P00734

KEGG DISEASE (16)

KEGG name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00835 Succinic semialdehyde dehydrogenase (SSADH) deficiency P51649 (related)
H01257 GABA-transaminase deficiency P80404 (related)
H00236 Congenital polycythemia Q9GZT9 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)

Diseases related to CTD interactions

3 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D002493 Central Nervous System Diseases C00019308
D003072 Cognition Disorders C00019308
D013118 Spinal Cord Diseases C00019308