| Organism name | Populus sieboldii |
|---|---|
| Genus | Populus |
| Family | Salicaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Populus |
|---|---|
| Linked NCBI taxonomy ID | 3689 |
| Linked level | genus |
| Family in NCBI taxonomy | Salicaceae |
|---|---|
| ID | 3688 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | rosids |
|---|---|
| ID | 71275 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00008219
|
Sakuranin
|
CHEMBL489338
CHEMBL495847 CHEMBL1998622 |
No. 12 | No. 14 |
|
|||
|
C00007885
|
Neosakuranin
|
CHEMBL495848
|
No. 36 | No. 13 |
|
|||
|
C00002672
|
Salicin
/ Saligenin beta-D-glucopyranoside |
CHEMBL334657
CHEMBL462997 CHEMBL1595746 |
C005696
|
5 / 1 / 4 | No. 45 | No. 72 |
|
|
|
C00006955
|
Gymnogrammene
|
No. 79 |
|
|||||
|
C00006933
|
2',4',6'-Trihydroxychalcone
|
CHEMBL129371
|
2 / 0 / 3 | No. 92 | No. 13 |
|
||
|
C00006952
|
2',4',6'-Trihydroxy-4-methoxychalcone
|
CHEMBL133588
|
No. 92 | No. 13 |
|
|||
|
C00006953
|
Neosakuranetin
|
No. 92 | No. 13 |
|
||||
|
C00006975
|
4,2',6'-Trihydroxy-3,4'-dimethoxychalcone
|
No. 92 | No. 13 |
|
||||
|
C00007233
|
Isosalipurpol
/ Chalconaringenin / Naringenin chalcone / trans-2',4,4',6'-Tetrahydroxychalcone / (2E)- 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-2-Propen-1-one |
CHEMBL338066
|
12 / 20 / 21 | No. 92 | No. 13 |
|
||
|
C00006973
|
3,4,2',4',6'-Pentahydroxychalcone
|
CHEMBL127409
|
2 / 0 / 3 | No. 92 | No. 13 |
|
||
|
C00006974
|
4,2',4',6'-Tetrahydroxy-3-methoxychalcone
|
No. 92 | No. 13 |
|
||||
|
C00041864
|
Siebolside A
|
CHEMBL523737
|
No. 532 |
|
||||
|
C00041865
|
Siebolside B
|
CHEMBL496072
|
No. 532 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00002672 C00006933 C00006973 C00007233 | 0 / 3 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00006933 C00006973 C00007233 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002672 C00007233 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00002672 C00007233 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00007233 | 7 / 3 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00007233 | 0 / 1 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00007233 | 0 / 0 |
| P11216 | Glycogen phosphorylase, brain form | Enzyme | C00002672 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00007233 | 4 / 3 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00002672 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00007233 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00007233 | 1 / 2 |
| P04062 | Glucosylceramidase | Enzyme | C00007233 | 6 / 4 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00007233 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|