Clerodendrum inerme

• Index
• Plant Species
• Metabolite list (23)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Clerodendrum inerme
Genus	Clerodendrum
Family	Labiatae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Clerodendrum inerme
Linked NCBI taxonomy ID	49994
Linked level	species

Family

Family in NCBI taxonomy	Lamiaceae
ID	4136

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (23)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00003836	Scutellarein 4'-methyl ether					No. 3	No. 15
C00002783	Kusaginin / Acteoside / Verbascoside	CHEMBL231853 CHEMBL444478 CHEMBL1364101	C058956	12 / 1 / 1	34 / 3	No. 33
C00030657	Leucosceptoside A	CHEMBL450121		1 / 0 / 0		No. 33
C00030516	Isoacteoside / Isoverbascoside	CHEMBL504873	C064683	6 / 5 / 4		No. 33
C00031274	Salidroside / Rhodioloside / (-)-Rhodioloside / Tyrosol alpha-(beta-D-glucopyranoside)	CHEMBL465208 CHEMBL1899113	C009172	3 / 0 / 0		No. 45	No. 72
C00010619	Monomelittoside					No. 100	No. 36
C00036634	6-Nonacosanone					No. 115
C00036403	11-Pentacosanone					No. 115
C00037004	Darendoside B	CHEMBL462940	C080861			No. 128	No. 72
C00030098	Verbasoside / (-)-Verbasoside / Decaffeoylverbascoside / (-)-Decaffeoylverbascoside	CHEMBL1779146				No. 128	No. 72
C00032760	(-)-Benzyl beta-primeveroside / Benzyl alcohol beta-D-xylopyranosyl (1->6)-beta-D-glucopyranoside	CHEMBL1371061	C069904	3 / 1 / 1		No. 128	No. 72
C00031281	Sammangaoside B / Summangaoside B / (-)-Sammangaoside B					No. 153
C00031280	Sammangaoside A / Staphylionoside H / (-)-Sammangaoside A	CHEMBL1814430				No. 153
C00035203	14,15-Dihydro-15beta-methoxy-3-epicaryoptin					No. 172	No. 43
C00035204	14,15-Dihydro-15-hydroxy-3-epicaryoptin					No. 172	No. 43
C00036351	(7S,8R)-Dehydrodiconiferyl alcohol 4-O-beta-glucopyranoside	CHEMBL1086907				No. 193
C00036352	(7S,8R)-Dehydrodiconiferyl alcohol 9-O-beta-glucopyranoside	CHEMBL466931				No. 193
C00010621	Melittoside					No. 222
C00029346	(Z)-3-Hexenyl beta-D-glucopyranoside / (-)-(Z)-3-Hexenyl-beta-glucopyranoside / (Z)-3-Hexen-1-ol-beta-D-glucopyranoside	CHEMBL2152486	C058860			No. 258	No. 73
C00036919	Clerodermic acid	CHEMBL228501				No. 405
C00037809	Seguinoside K					No. 411
C00036467	Leonuriside A / 2,6-Dimethoxy-p-hydroquinone 1-O-beta-glucopyranoside	CHEMBL464406		2 / 4 / 2		No. 678	No. 6
C00037783	Sammangaoside C					No. 1212

Human Protein / Gene in interactions

23 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00002783 C00031274 C00032760	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00002783 C00031274	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00002783 C00030657	0 / 0
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00002783	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00036467	0 / 0
P39900	Macrophage metalloelastase	M10A	C00030516	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00030516	2 / 2
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00031274	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002783	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00002783	1 / 1
P03956	Interstitial collagenase	M10A	C00030516	0 / 1
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00032760	1 / 1
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00002783	0 / 0
P00734	Prothrombin	S1A	C00036467	4 / 2
P45452	Collagenase 3	M10A	C00030516	1 / 1
P08253	72 kDa type IV collagenase	M10A	C00030516	1 / 3
Q9UNA4	DNA polymerase iota	Enzyme	C00002783	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00002783	0 / 0
P08254	Stromelysin-1	M10A	C00030516	1 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00002783	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00032760	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002783	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002783	0 / 0

34 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00002783
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00002783
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00002783
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00002783
894	CCND2, KIAK0002	cyclin D2	C00002783
896	CCND3	cyclin D3	C00002783
898	CCNE1, CCNE	cyclin E1	C00002783
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00002783
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00002783
1021	CDK6, PLSTIRE	cyclin-dependent kinase 6 (EC:2.7.11.22)	C00002783
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00002783
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00002783
3627	CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1	chemokine (C-X-C motif) ligand 10	C00002783
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00002783
1869	E2F1, E2F-1, RBAP1, RBBP3, RBP3	E2F transcription factor 1	C00002783
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00002783
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00002783
3458	IFNG, IFG, IFI	interferon, gamma	C00002783
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00002783
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00002783
3689	ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	C00002783
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00002783
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00002783
27035	NOX1, GP91-2, MOX1, NOH-1, NOH1	NADPH oxidase 1	C00002783
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002783
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00002783
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00002783
4087	SMAD2, JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2	SMAD family member 2	C00002783
4088	SMAD3, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3	SMAD family member 3	C00002783
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00002783
7039	TGFA, TFGA	transforming growth factor, alpha	C00002783
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00002783
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002783
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00002783

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions