Artocarpus communis
Species
KNApSAcK Entry
| Organism name | Artocarpus communis |
|---|---|
| Genus | Artocarpus |
| Family | Moraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Artocarpus altilis |
|---|---|
| Linked NCBI taxonomy ID | 194251 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Moraceae |
|---|---|
| ID | 3487 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (39)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00004032
|
Artocarpin
/ 2',4',5-Trihydroxy-7-methoxy-6-(3-methyl-1-butenyl)-3-(3-methyl-2-butenyl)flavone / 2-(2,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-6-(3-methyl-1-butenyl)-3-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one |
No. 14 | No. 15 |
|
||||
|
C00013413
|
Artocommunol CD
/ 2-(2,4-Dihydroxyphenyl)-3-[(2E)-3,7-dimethyl-2,6-octadienyl]-5,7-dihydroxy-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one |
No. 14 | No. 15 |
|
||||
|
C00004041
|
Dihydrocycloartomunin
|
No. 14 | No. 15 |
|
||||
|
C00013412
|
Cudraflavone C
/ 2',4',5,7-Tetrahydroxy-3,6-bis(3-methyl-2-butenyl)flavone / 2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-3,6-bis(3-methyl-2-butenyl)-4H-1-benzopyran-4-one |
CHEMBL485777
|
No. 14 | No. 15 |
|
|||
|
C00034929
|
Artochamin D
|
No. 14 | No. 15 |
|
||||
|
C00004103
|
Dihydroisocycloartomunin
/ 3,8,10-Trihydroxy-2-methoxy-11-(3-methyl-2-butenyl)-6-(2-methyl-1-propenyl)-6H,7H-[1]benzopyrano[4,3-b][1]benzopyran-7-one |
No. 14 | No. 15 |
|
||||
|
C00004099
|
Isocyclomulberrin
/ (+)-3,8,10-Trihydroxy-9-(3-methyl-2-butenyl)-6-(2-methyl-1-propenyl)-6H,7H-[1]benzopyrano[4,3-b][1]benzopyran-7-one |
CHEMBL485976
|
No. 14 | No. 15 |
|
|||
|
C00004102
|
Cyclocommunol
/ 3,8,10-Trihydroxy-6-(2-methyl-1-propenyl)-6H,7H-[1]benzopyrano[4,3-b][1]benzopyran-7-one |
No. 15 | No. 15 |
|
||||
|
C00004090
|
Licoflavone C
/ 8-Prenylapigenin / 5,7,4'-Trihydroxy-8-prenylflavone / 5,7-Dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one |
CHEMBL371562
|
1 / 0 / 0 | No. 15 | No. 15 |
|
||
|
C00034939
|
Cyclocomunomethonol
/ (+)-Cyclocomunomethonol |
No. 15 | No. 15 |
|
||||
|
C00004105
|
KB-2
/ 5,2',4',5'-Tetrahydroxy-3-(3-hydroxy-3-methylbutyl)-6'',6''-dimethylpyrano[2'',3'':7,8]flavone |
No. 18 | No. 15 |
|
||||
|
C00041222
|
(-)-Cudraflavone A
|
CHEMBL230558
|
No. 18 | No. 15 |
|
|||
|
C00004106
|
KB 3
/ Artonin E / 5-Hydroxy-8,8-dimethyl-3-(3-methyl-2-butenyl)-2-(2,4,5-trihydroxyphenyl)-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one |
CHEMBL463106
|
C066727
|
No. 18 | No. 15 |
|
||
|
C00041223
|
(-)-Cycloartocarpin
|
CHEMBL525350
|
No. 18 | No. 15 |
|
|||
|
C00013499
|
Artocommunol CA
/ (+)-6-Hydroxy-11-methoxy-3,3-dimethyl-8-(2-methyl-1-propenyl)-3H,7H,8H-bis[1]benzopyrano[4,3-b:6',5'-e]pyran-7-one |
No. 18 | No. 15 |
|
||||
|
C00004055
|
Cycloartomunin
/ 6,12-Dihydroxy-11-methoxy-3,3-dimethyl-8-(2-methyl-1-propenyl)-3H,7H,8H-bis[1]benzopyrano[4,3-b:6',5'-e]pyran-7-one |
No. 18 | No. 15 |
|
||||
|
C00004029
|
Cyclomorusin
/ Cyclomulberrochromene / 6,11-Dihydroxy-3,3-dimethyl-8-(2-methyl-1-propenyl)-3H,7H,8H-bis[1]benzopyrano[4,3-b:6',5'-e]pyran-7-one |
CHEMBL1770313
|
1 / 0 / 0 | No. 18 | No. 15 |
|
||
|
C00013488
|
Cycloartomunoxanthone
/ 5a,6-Dihydro-1,8-dihydroxy-3-methoxy-5,5,11,11-tetramethyl-5H,7H,11H-benzofuro[3,4-bc]pyrano[3,2-h]xanthen-7-one |
No. 18 | No. 15 |
|
||||
|
C00013485
|
Cycloartobiloxanthone
/ 5a,6-Dihydro-1,3,8-trihydroxy-5,5,11,11-tetramethyl-5H,7H,11H-benzofuro[3,4-bc]pyrano[3,2-h]xanthen-7-one |
CHEMBL516519
|
2 / 0 / 0 | No. 18 | No. 15 |
|
||
|
C00044541
|
Artocommunol CE
/ (+)-Artocommunol CE |
No. 18 | No. 15 |
|
||||
|
C00034930
|
Artomunoflavanone
/ (+)-Artomunoflavanone |
No. 25 | No. 14 |
|
||||
|
C00008452
|
Euchrenone a7
/ (2S)-Euchrenone a7 / (-)-(2S)-Euchrenone a7 |
CHEMBL457686
|
1 / 2 / 2 | No. 28 | No. 14 |
|
||
|
C00044540
|
Artocommunol CB
|
No. 44 |
|
|||||
|
C00013490
|
Artonol E
/ 6,7-Dihydro-5,9,14-trihydroxy-11-methoxy-3,3-dimethyl-6-(1-methylethenyl)-3H,8H-[1]benzopyrano[7,6-c]xanthen-8-one |
No. 44 |
|
|||||
|
C00013492
|
Artonol C
/ 9,12-Dihydro-6,10,15-trihydroxy-3,3,12,12-tetramethyl-9-(1-methylethenyl)-3H,7H,8H-[1]benzopyrano[7,6-c]pyrano[3,2-h]xanthen-7-one |
No. 44 |
|
|||||
|
C00013489
|
Artonin F
/ 5a,6-Dihydro-1,3,8-trihydroxy-5,5,11,11-tetramethyl-9-(3-methyl-2-butenyl)-5H,7H,11H-benzofuro[3,4-bc]pyrano[3,2-h]xanthen-7-one |
No. 44 |
|
|||||
|
C00013484
|
Artomunoxanthone
/ 8,9-Dihydro-6,10,13-trihydroxy-11-methoxy-3,3-dimethyl-9-(1-methylethenyl)-3H,7H-benzo[c]pyrano[3,2-h]xanthen-7-one |
No. 44 |
|
|||||
|
C00034931
|
Artomunoisoxanthone
/ (+)-Artomunoisoxanthone |
No. 44 |
|
|||||
|
C00034941
|
Dihydroartomunoxanthone
/ (+)-Dihydroartomunoxanthone |
No. 44 |
|
|||||
|
C00004104
|
Artobiloxanthone
/ 8,9-Dihydro-6,10,11,13-tetrahydroxy-3,3-dimethyl-9-(1-methylethenyl)-3H,7H-benzo[c]pyrano[3,2-h]xanthen-7-one |
CHEMBL1099162
|
2 / 0 / 0 | No. 44 |
|
|||
|
C00007091
|
Morachalcone A
|
CHEMBL465880
|
1 / 2 / 2 | No. 133 | No. 13 |
|
||
|
C00008018
|
2-Geranyl-3,4,2',4'-tetrahydroxydihydrochalcone
|
CHEMBL523392
|
1 / 1 / 2 | No. 326 |
|
|||
|
C00008014
|
3-Geranyl-4,2',4'-trihydroxydihydrochalcone
|
No. 326 |
|
|||||
|
C00014452
|
Gemichalcone B
/ 3'-(4-Coumaroyloxy-3-methylbutyl-2(Z)-enyl)-4,2',4'-trihydroxychalcone |
CHEMBL497716
CHEMBL517334 |
2 / 0 / 3 | No. 1706 |
|
|||
|
C00014483
|
Gemichalcone C
/ 3'-(4-Feruloyloxy-3-methylbutyl-2(Z)-enyl)-2,4,2',4'-tetrahydroxychalcone |
CHEMBL463638
CHEMBL499860 |
1 / 2 / 2 | No. 1706 |
|
|||
|
C00013457
|
Artocommunol CC
/ (9S)-8,9-Dihydro-6,12-dihydroxy-9-(1-hydroxy-1-methylethyl)-3-methyl-3-(4-methyl-3-pentenyl)-3H,7H-pyrano[2',3':7,8][1]benzopyrano[3,2-d][1]benzoxepin-7-one |
No. 4175 |
|
|||||
|
C00013483
|
Artomunoxanthentrione
/ 6-Hydroxy-11-methoxy-3,3-dimethyl-9-(1-methylethenyl)-3H,7H-benzo[c]pyrano[3,2-h]xanthene-7,10,13-trione |
No. 4312 |
|
|||||
|
C00034928
|
Artochamin B
/ (-)-Artochamin B |
No. 7043 |
|
|||||
|
C00013494
|
Artonol D
/ 6-Hydroxy-3,3,12,12-tetramethyl-9-(1-methylethenyl)-3H,7H,8H-[1]benzopyrano[7,6-c]pyrano[3,2-h]xanthene-7,10,15(9H,12H)-trione |
No. 7163 |
|
Human Protein / Gene in interactions
8 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00007091 C00008452 C00014483 | 2 / 2 |
| Q04206 | Transcription factor p65 | Transcription Factor | C00004104 C00013485 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00004104 C00013485 | 0 / 0 |
| P43235 | Cathepsin K | C1A | C00008018 | 1 / 2 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00014452 | 0 / 0 |
| P56817 | Beta-secretase 1 | A1A | C00004029 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00004090 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00014452 | 0 / 3 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (3)
| OMIM | preferred title | UniProt |
|---|---|---|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #265800 | Pycnodysostosis |
P43235
|
KEGG DISEASE (7)
| KEGG | name | UniProt |
|---|---|---|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P11511
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00273 | Pycnodysostosis |
P43235
(related)
|
| H00425 | Lysosomal cysteine protease deficiencies |
P43235
(related)
|