| Organism name | Capparis flavicans | 
|---|---|
| Genus | Capparis | 
| Family | Capparaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Capparis | 
|---|---|
| Linked NCBI taxonomy ID | 13394 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Capparaceae | 
|---|---|
| ID | 301453 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | rosids | 
|---|---|
| ID | 71275 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00029329   | Roseoside / Roseoside A / Roseoside II / (6S,9R)-Roseoside / Vomifoliol beta-D-glucopyranoside |   | ||||||
| C00019029   | Tachioside / 3-Methoxy-4-hydroxyphenyl-beta-D-glucopyranoside | CHEMBL1077078 | No. 45 | No. 72 |   | |||
| C00032471   | Vanilloloside | CHEMBL468568 | 1 / 0 / 3 | No. 45 | No. 72 |   | ||
| C00019030   | Isotachioside / Methoxy-hydroquinone-1-O-beta-D-glucopyranoside / 4-Hydroxy-2-methoxyphenyl-beta-D-Glucopyranoside | No. 45 | No. 72 |   | ||||
| C00048144   | Spionoside B | CHEMBL1088198 | No. 153 |   | ||||
| C00047704   | Alangilignoside D | No. 174 | No. 22 |   | ||||
| C00047703   | Alangilignoside C / (+)-Alangilignoside C | No. 174 | No. 22 |   | ||||
| C00047702   | Alangilignoside B / (-)-Alangilignoside B | No. 193 |   | |||||
| C00000604   | (-)-Secoisolariciresinol | CHEMBL368347 | C060283 | 2 / 1 / 1 | 1 / 0 | No. 282 | No. 21 |   | 
| C00037294   | Icariside B1 / (-)-Icariside B1 | No. 316 |   | |||||
| C00042206   | Alangionoside C | No. 316 |   | |||||
| C00033999   | Koaburaside | CHEMBL513117 | 2 / 4 / 2 | No. 678 | No. 6 |   | ||
| C00007444   | Adenosine | CHEMBL477 CHEMBL11909 CHEMBL20247 CHEMBL1090 CHEMBL91573 CHEMBL145188 CHEMBL1236872 CHEMBL1413677 CHEMBL2051971 | D000241 | 61 / 89 / 68 | 33 / 35 | No. 1060 |   | |
| C00032702   | Americanol A | C074373 | No. 1955 |   | ||||
| C00033058   | Isoamericanol A | CHEMBL1082871 | C074374 | No. 1955 |   | |||
| C00037341   | Isoprincepin | CHEMBL1086906 | No. 3499 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000604 C00007444 | 1 / 0 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000604 C00007444 | 0 / 1 | 
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00007444 | 1 / 0 | 
| Q16637 | Survival motor neuron protein | Unclassified protein | C00007444 | 4 / 1 | 
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00007444 | 2 / 0 | 
| P20839 | Inosine-5'-monophosphate dehydrogenase 1 | Oxidoreductase | C00007444 | 2 / 2 | 
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00032471 | 0 / 3 | 
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00007444 | 2 / 2 | 
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00007444 | 0 / 0 | 
| P04406 | Glyceraldehyde-3-phosphate dehydrogenase | Enzyme | C00007444 | 0 / 0 | 
| P02545 | Prelamin-A/C | Unclassified protein | C00007444 | 11 / 10 | 
| Q8TD43 | Transient receptor potential cation channel subfamily M member 4 | Unclassified protein | C00007444 | 1 / 1 | 
| P00813 | Adenosine deaminase | Hydrolase | C00007444 | 1 / 1 | 
| P12268 | Inosine-5'-monophosphate dehydrogenase 2 | Oxidoreductase | C00007444 | 0 / 0 | 
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00007444 | 3 / 2 | 
| P29275 | Adenosine receptor A2b | Adenosine receptor | C00007444 | 0 / 0 | 
| P04183 | Thymidine kinase, cytosolic | Enzyme | C00007444 | 0 / 1 | 
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00007444 | 0 / 1 | 
| Q9HBX9 | Relaxin receptor 1 | Relaxin receptor | C00007444 | 0 / 0 | 
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00007444 | 1 / 8 | 
| P47901 | Vasopressin V1b receptor | Vasopressin and oxytocin receptor | C00007444 | 0 / 0 | 
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00007444 | 0 / 0 | 
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00007444 | 0 / 0 | 
| P39748 | Flap endonuclease 1 | Enzyme | C00007444 | 0 / 0 | 
| P42858 | Huntingtin | Unclassified protein | C00007444 | 1 / 1 | 
| O75496 | Geminin | Unclassified protein | C00007444 | 0 / 0 | 
| P27487 | Dipeptidyl peptidase 4 | S9B | C00007444 | 0 / 1 | 
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00007444 | 7 / 3 | 
| P42226 | Signal transducer and activator of transcription 6 | Unclassified protein | C00007444 | 0 / 0 | 
| P00734 | Prothrombin | S1A | C00033999 | 4 / 2 | 
| P06213 | Insulin receptor | TK tyrosine-protein kinase INSR subfamily | C00007444 | 5 / 4 | 
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00007444 | 5 / 9 | 
| P09619 | Platelet-derived growth factor receptor beta | Pdgfr | C00007444 | 5 / 1 | 
| P55263 | Adenosine kinase | Enzyme | C00007444 | 1 / 0 | 
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00007444 | 0 / 0 | 
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00007444 | 0 / 0 | 
| Q8WXD0 | Relaxin receptor 2 | Relaxin receptor | C00007444 | 1 / 1 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00007444 | 0 / 0 | 
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00007444 | 0 / 0 | 
| P05771 | Protein kinase C beta type | Alpha | C00007444 | 0 / 0 | 
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00007444 | 1 / 1 | 
| P23526 | Adenosylhomocysteinase | Enzyme | C00007444 | 1 / 1 | 
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00007444 | 0 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00007444 | 4 / 3 | 
| Q6DHV7 | Adenosine deaminase-like protein | Enzyme | C00007444 | 0 / 0 | 
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00007444 | 0 / 0 | 
| Q9GZV3 | High affinity choline transporter 1 | Choline Na-symporter | C00007444 | 1 / 0 | 
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00007444 | 0 / 0 | 
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00033999 | 0 / 0 | 
| O00255 | Menin | Unclassified protein | C00007444 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00007444 | 1 / 2 | 
| P11362 | Fibroblast growth factor receptor 1 | Fgfr | C00007444 | 4 / 5 | 
| P22455 | Fibroblast growth factor receptor 4 | Fgfr | C00007444 | 0 / 0 | 
| P22607 | Fibroblast growth factor receptor 3 | Fgfr | C00007444 | 14 / 6 | 
| P21802 | Fibroblast growth factor receptor 2 | TK tyrosine-protein kinase TLK subfamily | C00007444 | 9 / 3 | 
| P07205 | Phosphoglycerate kinase 2 | Enzyme | C00007444 | 0 / 0 | 
| P00558 | Phosphoglycerate kinase 1 | Enzyme | C00007444 | 1 / 1 | 
| Q9UBF8 | Phosphatidylinositol 4-kinase beta | Enzyme | C00007444 | 0 / 0 | 
| Q8TCG2 | Phosphatidylinositol 4-kinase type 2-beta | Enzyme | C00007444 | 0 / 0 | 
| Q9BTU6 | Phosphatidylinositol 4-kinase type 2-alpha | Enzyme | C00007444 | 0 / 0 | 
| P42356 | Phosphatidylinositol 4-kinase alpha | Enzyme | C00007444 | 0 / 0 | 
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00007444 | 0 / 1 | 
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00007444 | 1 / 0 | 
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00007444 | 0 / 0 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 8856 | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR | nuclear receptor subfamily 1, group I, member 2 | C00000604 | 
| 100 | ADA | adenosine deaminase (EC:3.5.4.4) | C00007444 | 
| 134 | ADORA1, RDC7 | adenosine A1 receptor | C00007444 | 
| 135 | ADORA2A, A2aR, ADORA2, RDC8 | adenosine A2a receptor | C00007444 | 
| 140 | ADORA3, A3AR, AD026, bA552M11.5 | adenosine A3 receptor | C00007444 | 
| 248 | ALPI, IAP | alkaline phosphatase, intestinal (EC:3.1.3.1) | C00007444 | 
| 581 | BAX, BCL2L4 | BCL2-associated X protein | C00007444 | 
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 | C00007444 | 
| 329 | BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 | baculoviral IAP repeat containing 2 | C00007444 | 
| 330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 | C00007444 | 
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | C00007444 | 
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) | C00007444 | 
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) | C00007444 | 
| 929 | CD14 | CD14 molecule | C00007444 | 
| 8837 | CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS | CASP8 and FADD-like apoptosis regulator | C00007444 | 
| 1080 | CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | C00007444 | 
| 56616 | DIABLO, DFNA64, SMAC | diablo, IAP-binding mitochondrial protein | C00007444 | 
| 1803 | DPP4, ADABP, ADCP2, CD26, DPPIV, TP103 | dipeptidyl-peptidase 4 (EC:3.4.14.5) | C00007444 | 
| 8772 | FADD, MORT1 | Fas (TNFRSF6)-associated via death domain | C00007444 | 
| 356 | FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 | Fas ligand (TNF superfamily, member 6) | C00007444 | 
| 3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | C00007444 | 
| 23643 | LY96, ESOP-1, MD-2, MD2, ly-96 | lymphocyte antigen 96 | C00007444 | 
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) | C00007444 | 
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) | C00007444 | 
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog | C00007444 | 
| 10891 | PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | C00007444 | 
| 9154 | SLC28A1, CNT1, HCNT1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 | C00007444 | 
| 9153 | SLC28A2, CNT2, HCNT2, HsT17153, SPNT1 | solute carrier family 28 (concentrative nucleoside transporter), member 2 | C00007444 | 
| 2030 | SLC29A1, ENT1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | C00007444 | 
| 3177 | SLC29A2, DER12, ENT2, HNP36 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 | C00007444 | 
| 55315 | SLC29A3, ENT3, HCLAP, HJCD, PHID | solute carrier family 29 (equilibrative nucleoside transporter), member 3 | C00007444 | 
| 7099 | TLR4, ARMD10, CD284, TLR-4, TOLL | toll-like receptor 4 | C00007444 | 
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor | C00007444 | 
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A | C00007444 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #100800 | Achondroplasia; ach | P22607 | 
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah | P63092 | 
| #207410 | Antley-bixler syndrome without genital anomalies or disordered steroidogenesis; abs2 | P21802 | 
| #101200 | Apert syndrome | P21802 | 
| #615007 | Basal ganglia calcification, idiopathic, 4; ibgc4 | P09619 | 
| #123790 | Beare-stevenson cutis gyrata syndrome; bstvs | P21802 | 
| #614592 | Bent bone dysplasia syndrome; bbds | P21802 | 
| #109800 | Bladder cancer | P22607 | 
| #610474 | Camptodactyly, tall stature, and hearing loss syndrome | P22607 | 
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a | P02545 | 
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism | P02545 | 
| #603956 | Cervical cancer | P22607 | 
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 | P02545 | 
| #123500 | Crouzon syndrome | P21802 | 
| #612247 | Crouzon syndrome with acanthosis nigricans; can | P22607 | 
| #219050 | Cryptorchidism, unilateral or bilateral | Q8WXD0 | 
| #610549 | Diabetes mellitus, insulin-resistant, with acanthosis nigricans | P06213 | 
| #125853 | Diabetes mellitus, noninsulin-dependent; niddm | P06213 | 
| #246200 | Donohue syndrome | P06213 | 
| #609535 | Drug metabolism, poor, cyp2c19-related | P33261 | 
| #608902 | Drug metabolism, poor, cyp2d6-related | P10635 | 
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 | P02545 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #613659 | Gastric cancer | P04626 | 
| #137215 | Gastric cancer, hereditary diffuse; hdgc | P04626 | 
| #137800 | Glioma susceptibility 1; glm1 | O75874 P04626 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #610140 | Heart-hand syndrome, slovenian type | P02545 | 
| #143100 | Huntington disease; hd | P42858 | 
| #176670 | Hutchinson-gilford progeria syndrome; hgps | P02545 | 
| #609968 | Hyperinsulinemic hypoglycemia, familial, 5; hhf5 | P06213 | 
| #614300 | Hypermethioninemia due to adenosine kinase deficiency | P55263 | 
| #613752 | Hypermethioninemia with s-adenosylhomocysteine hydrolase deficiency | P23526 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #603373 | Hyperthyroidism, familial gestational | P16473 | 
| #609152 | Hyperthyroidism, nonautoimmune | P16473 | 
| #146000 | Hypochondroplasia; hch | P22607 | 
| #147950 | Hypogonadotropic hypogonadism 2 with or without anosmia; hh2 | P11362 | 
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 | P16473 | 
| #123150 | Jackson-weiss syndrome; jws | P21802 | 
| #607785 | Juvenile myelomonocytic leukemia; jmml | P09619 | 
| #182000 | Keratosis, seborrheic | P22607 | 
| #149730 | Lacrimoauriculodentodigital syndrome; ladd | P21802 P22607 | 
| #613837 | Leber congenital amaurosis 11; lca11 | P20839 | 
| #601626 | Leukemia, acute myeloid; aml | P09619 | 
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 | P02545 | 
| #613688 | Long qt syndrome 2; lqt2 | Q12809 | 
| #211980 | Lung cancer | P00533 P04626 | 
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada | P02545 | 
| #174800 | Mccune-albright syndrome; mas | P63092 | 
| #602849 | Muenke syndrome; mnkes | P22607 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #613205 | Muscular dystrophy, congenital, lmna-related | P02545 | 
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b | P02545 | 
| #254500 | Myeloma, multiple | P22607 | 
| #131440 | Myeloproliferative disorder, chronic, with eosinophilia | P09619 | 
| #228550 | Myofibromatosis, infantile, 1; imf1 | P09619 | 
| #158580 | Neuronopathy, distal hereditary motor, type viia; hmn7a | Q9GZV3 | 
| #162900 | Nevus, epidermal | P22607 | 
| #166350 | Osseous heteroplasia, progressive; poh | P63092 | 
| #166250 | Osteoglophonic dysplasia; ogd | P11362 | 
| #167000 | Ovarian cancer | P04626 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #101600 | Pfeiffer syndrome | P11362 P21802 | 
| #300653 | Phosphoglycerate kinase 1 deficiency | P00558 | 
| #172700 | Pick disease of brain | P10636 | 
| #262190 | Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities | P06213 | 
| #102200 | Pituitary adenoma, growth hormone-secreting | P63092 | 
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 | P00734 | 
| #604559 | Progressive familial heart block, type ib; pfhb1b | Q8TD43 | 
| #613679 | Prothrombin deficiency, congenital | P00734 | 
| #103580 | Pseudohypoparathyroidism, type ia; php1a | P63092 | 
| #603233 | Pseudohypoparathyroidism, type ib; php1b | P63092 | 
| #612462 | Pseudohypoparathyroidism, type ic; php1c | P63092 | 
| #607276 | Resting heart rate, variation in | P08588 | 
| #275210 | Restrictive dermopathy, lethal | P02545 | 
| #180105 | Retinitis pigmentosa 10; rp10 | P20839 | 
| #609579 | Scaphocephaly, maxillary retrusion, and mental retardation | P21802 | 
| #604906 | Schizophrenia 9; sczd9 | P49798 | 
| #181500 | Schizophrenia; sczd | P49798 | 
| #102700 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-negative, nk cell-negative, due to adenosine deaminase deficiency | P00813 | 
| #609620 | Short qt syndrome 1; sqt1 | Q12809 | 
| #253300 | Spinal muscular atrophy, type i; sma1 | Q16637 | 
| #253550 | Spinal muscular atrophy, type ii; sma2 | Q16637 | 
| #253400 | Spinal muscular atrophy, type iii; sma3 | Q16637 | 
| #271150 | Spinal muscular atrophy, type iv; sma4 | Q16637 | 
| #601367 | Stroke, ischemic | P00734 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| #273300 | Testicular germ cell tumor; tgct | P22607 | 
| #187600 | Thanatophoric dysplasia, type i; td1 | P22607 | 
| #187601 | Thanatophoric dysplasia, type ii; td2 | P22607 | 
| #188050 | Thrombophilia due to thrombin defect; thph1 | P00734 | 
| #190440 | Trigonocephaly 1; trigno1 | P11362 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H00016 | Oral cancer | P00533
                            (related) P00533 (marker) | 
| H00017 | Esophageal cancer | P00533
                            (related) P35354 (related) | 
| H00018 | Gastric cancer | P00533
                            (related) P04626 (related) P21802 (related) | 
| H00022 | Bladder cancer | P00533
                            (related) P04626 (related) P22607 (related) | 
| H00028 | Choriocarcinoma | P00533
                            (related) P04626 (related) | 
| H00030 | Cervical cancer | P00533
                            (related) P04626 (related) | 
| H00042 | Glioma | P00533
                            (related) P00533 (marker) P09619 (related) | 
| H00055 | Laryngeal cancer | P00533
                            (related) P00533 (marker) | 
| H00664 | Anemia due to disorders of glycolytic enzymes | P00558
                            (related) | 
| H00223 | Inherited thrombophilia | P00734
                            (related) | 
| H01254 | Congenital prothrombin deficiency | P00734
                            (related) | 
| H00092 | T-B-Severe combined immunodeficiencies (SCIDs) | P00813
                            (related) | 
| H00264 | Charcot-Marie-Tooth disease (CMT) | P02545
                            (related) | 
| H00294 | Dilated cardiomyopathy (DCM) | P02545
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P02545
                            (related) | 
| H00563 | Emery-Dreifuss muscular dystrophy | P02545
                            (related) | 
| H00590 | Congenital muscular dystrophies (CMD/MDC) | P02545
                            (related) | 
| H00593 | Limb-girdle muscular dystrophy (LGMD) | P02545
                            (related) | 
| H00601 | Hutchinson-Gilford progeria syndrome | P02545
                            (related) | 
| H00663 | Restrictive dermopathy | P02545
                            (related) | 
| H00665 | Mandibuloacral dysplasia | P02545
                            (related) | 
| H01216 | Left ventricular noncompaction (LVNC) | P02545
                            (related) | 
| H00005 | Chronic lymphocytic leukemia (CLL) | P04183
                            (marker) | 
| H00019 | Pancreatic cancer | P04626
                            (related) | 
| H00026 | Endometrial Cancer | P04626
                            (related) | 
| H00027 | Ovarian cancer | P04626
                            (related) | 
| H00031 | Breast cancer | P04626
                            (related) P04626 (marker) | 
| H00046 | Cholangiocarcinoma | P04626
                            (related) P35354 (related) | 
| H00719 | Leprechaunism | P06213
                            (related) | 
| H00942 | Rabson-Mendenhall syndrome | P06213
                            (related) | 
| H01228 | Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) | P06213
                            (related) | 
| H01267 | Familial hyperinsulinemic hypoglycemia (HHF) | P06213
                            (related) | 
| H00079 | Asthma | P07550
                            (related) | 
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00255 | Hypogonadotropic hypogonadism | P11362
                            (related) | 
| H00443 | Osteoglophonic dysplasia (OD) | P11362
                            (related) | 
| H00458 | Craniosynostosis | P11362
                            (related) P21802 (related) P22607 (related) | 
| H00516 | Isolated orofacial clefts | P11362
                            (related) | 
| H01207 | Trigonocephaly | P11362
                            (related) | 
| H01205 | Coumarin resistance | P11712
                            (related) | 
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) | P16473
                            (related) | 
| H01269 | Congenital hyperthyroidism | P16473
                            (related) | 
| H00527 | Retinitis pigmentosa (RP) | P20839
                            (related) | 
| H00837 | Leber congenital amaurosis (LCR) | P20839
                            (related) | 
| H00642 | Lacrimo-auriculo-dento-digital syndrome (LADD) | P21802
                            (related) P22607 (related) | 
| H00010 | Multiple myeloma | P22607
                            (related) | 
| H00505 | FGFR3-related short limb skeletal dysplasias | P22607
                            (related) | 
| H00997 | CATSHL syndrome | P22607
                            (related) | 
| H00184 | Hypermethioninemia | P23526
                            (related) | 
| H00032 | Thyroid cancer | P27487
                            (marker) | 
| H01171 | Poor drug metabolism (PM) | P33261
                            (related) | 
| H00025 | Penile cancer | P35354
                            (related) | 
| H00059 | Huntington's disease (HD) | P42858
                            (related) | 
| H00244 | Pseudohypoparathyroidism | P63092
                            (related) | 
| H00441 | Progressive osseous heteroplasia (POH) | P63092
                            (related) | 
| H00501 | Fibrous dysplasia, polyostotic | P63092
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q03164
                            (related) Q03164 (marker) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00720 | Long QT syndrome | Q12809
                            (related) | 
| H00725 | Short QT syndrome | Q12809
                            (related) | 
| H00455 | Spinal muscular atrophy (SMA) | Q16637
                            (related) | 
| H01263 | Progressive cardiac conduction defect (PCCD) | Q8TD43
                            (related) | 
| H00609 | 46,XY disorders of sex development (Other) | Q8WXD0
                            (related) | 
| MESH or OMIM | name | KNApSAcK metabolite | 
|---|---|---|
| D001145 | Arrhythmias, Cardiac | C00007444 | 
| D001249 | Asthma | C00007444 | 
| D001282 | Atrial Flutter | C00007444 | 
| D054537 | Atrioventricular Block | C00007444 | 
| D001321 | Autistic Disorder | C00007444 | 
| D001919 | Bradycardia | C00007444 | 
| D002545 | Brain Ischemia | C00007444 | 
| D001986 | Bronchial Spasm | C00007444 | 
| D009202 | Cardiomyopathies | C00007444 | 
| D002389 | Catatonia | C00007444 | 
| D002637 | Chest Pain | C00007444 | 
| D004244 | Dizziness | C00007444 | 
| D004827 | Epilepsy | C00007444 | 
| D004830 | Epilepsy, Tonic-Clonic | C00007444 | 
| D005119 | Extravasation of Diagnostic and Therapeutic Materials | C00007444 | 
| D006333 | Heart Failure | C00007444 | 
| D006930 | Hyperalgesia | C00007444 | 
| D006940 | Hyperemia | C00007444 | 
| D006973 | Hypertension | C00007444 | 
| D006977 | Hypertension, Renal | C00007444 | 
| D007022 | Hypotension | C00007444 | 
| D007174 | Impulse Control Disorders | C00007444 | 
| D008106 | Liver Cirrhosis, Experimental | C00007444 | 
| D017202 | Myocardial Ischemia | C00007444 | 
| D009336 | Necrosis | C00007444 | 
| D009410 | Nerve Degeneration | C00007444 | 
| D009422 | Nervous System Diseases | C00007444 | 
| D010146 | Pain | C00007444 | 
| D012640 | Seizures | C00007444 | 
| D054138 | Sinus Arrest, Cardiac | C00007444 | 
| D013610 | Tachycardia | C00007444 | 
| D013617 | Tachycardia, Supraventricular | C00007444 | 
| D017180 | Tachycardia, Ventricular | C00007444 | 
| D014202 | Tremor | C00007444 | 
| D014693 | Ventricular Fibrillation | C00007444 |