Tephrosia purpurea
Species
KNApSAcK Entry
| Organism name | Tephrosia purpurea |
|---|---|
| Genus | Tephrosia |
| Family | Fabaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Tephrosia purpurea |
|---|---|
| Linked NCBI taxonomy ID | 228354 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Natural Activity
List (14)
| Species | Activity |
|---|---|
| Tephrosia purpurea (L.) Pers. | Alexeteric |
| Tephrosia purpurea (L.) Pers. | Alterative |
| Tephrosia purpurea (L.) Pers. | Antipyretic |
| Tephrosia purpurea (L.) Pers. | Bitter |
| Tephrosia purpurea (L.) Pers. | Cholagogue |
| Tephrosia purpurea (L.) Pers. | Deobstruent |
| Tephrosia purpurea (L.) Pers. | Depurative |
| Tephrosia purpurea (L.) Pers. | Diaphoretic |
| Tephrosia purpurea (L.) Pers. | Diuretic |
| Tephrosia purpurea (L.) Pers. | Insecticide |
| Tephrosia purpurea (L.) Pers. | Laxative |
| Tephrosia purpurea (L.) Pers. | Piscicide |
| Tephrosia purpurea (L.) Pers. | Tonic |
| Tephrosia purpurea (L.) Pers. | Vermifuge |
Metabolite list (38)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00019015
|
7,4'-Dihydroxy-3',5'-dimethoxyisoflavone
|
CHEMBL457942
|
No. 3 | No. 15 |
|
|||
|
C00003749
|
Lupeol
/ Lupenol / (+)-Lupenol |
CHEMBL289191
CHEMBL459702 |
C010480
|
3 / 0 / 0 | 2 / 6 | No. 23 | No. 51 |
|
|
C00009601
|
Dehydrodeguelin
/ 6a,12a-Dehydrodeguelin |
CHEMBL465673
|
No. 24 | No. 15 |
|
|||
|
C00019016
|
Lanceolatin B (flavonoid)
|
CHEMBL224157
|
1 / 0 / 0 | No. 35 | No. 15 |
|
||
|
C00013443
|
Pongaglabol
/ 5-Hydroxy-2-phenyl-4H-furo[2,3-h]-1-benzopyran-4-one |
No. 35 | No. 15 |
|
||||
|
C00005089
|
Karanjin
/ 3-Methoxy-2-phenyl-4H-Furo[2,3-h]-1-benzopyran-4-one |
CHEMBL208484
|
C052068
|
20 / 21 / 18 | No. 35 | No. 15 |
|
|
|
C00003672
|
Sitosterol
/ beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol |
CHEMBL221542
CHEMBL1398443 CHEMBL1875388 |
17 / 19 / 12 | No. 53 | No. 11 |
|
||
|
C00019955
|
2-Methoxy-3,9-dihydroxycoumestone
|
No. 54 | No. 17 |
|
||||
|
C00002546
|
Inermin
/ Maackiain / (-)-Maackiain / Demethylpterocarpin / 3-Hydroxy-8,9-methylenedioxypterocarpan |
CHEMBL334918
CHEMBL239047 CHEMBL445279 |
3 / 2 / 3 | No. 66 | No. 15 |
|
||
|
C00002547
|
(-)-Medicarpin
/ 3-Hydroxy-9-methoxypterocarpan |
CHEMBL238845
CHEMBL413297 |
C047353
|
3 / 1 / 1 | No. 66 | No. 15 |
|
|
|
C00009623
|
4-Methoxymaackiain
|
CHEMBL458847
|
No. 66 | No. 15 |
|
|||
|
C00006450
|
Lanceolatin B
|
No. 88 |
|
|||||
|
C00006449
|
Lanceolatin A(biflavonoid)
|
No. 88 |
|
|||||
|
C00008132
|
(-)-Isolonchocarpin
|
No. 127 | No. 14 |
|
||||
|
C00007002
|
Purpurenone
/ 6'-Demethoxypraecansone B |
No. 130 |
|
|||||
|
C00002537
|
Rotenolone
/ 12a-Hydroxyrotenone |
CHEMBL240545
|
No. 281 | No. 15 |
|
|||
|
C00009442
|
Maximaisoflavone C
|
CHEMBL1966368
|
No. 354 |
|
||||
|
C00019318
|
Fraxinol
/ 5,7-Dimethoxy-6-hydroxycoumarin |
CHEMBL611349
|
No. 364 | No. 25 |
|
|||
|
C00002522
|
Deguelin
/ (-)-cis-Deguelin |
CHEMBL393417
CHEMBL1592086 |
C107676
|
12 / 20 / 45 | 86 / 10 | No. 589 | No. 15 |
|
|
C00048435
|
Isoglabratephrin
/ (+)-Isoglabratephrin |
CHEMBL209361
|
No. 646 |
|
||||
|
C00013466
|
Semiglabrin
/ (-)-Semiglabrin / (7aS,10R,10aR)-10-(Acetyloxy)-7a,9,10,10a-tetrahydro-9,9-dimethyl-2-phenyl-4H-furo[3',2':4,5]furo[2,3-h]-1-benzopyran-4-one |
CHEMBL376949
CHEMBL377111 CHEMBL517326 |
No. 646 |
|
||||
|
C00013464
|
Glabratephrin
/ (3R,4R)-rel-(-)-4-(Acetyloxy)-4,5-dihydro-5,5-dimethyl-2'-phenylspiro[furan-3(2H),9'(8'H)-[4H]furo[2,3-h][1]benzopyran]-2,4'-dione |
CHEMBL209361
|
No. 646 |
|
||||
|
C00048553
|
Tephropurpulin A
/ (+)-Tephropurpulin A |
No. 646 |
|
|||||
|
C00007029
|
Tephrone
|
CHEMBL407578
CHEMBL1320141 CHEMBL1898417 |
6 / 6 / 6 | No. 676 |
|
|||
|
C00000615
|
Caffeic acid
|
CHEMBL145
CHEMBL1320034 |
68 / 64 / 63 | No. 904 | No. 6 |
|
||
|
C00014302
|
Tephrorin B
/ (+)-Tephrorin B |
No. 1090 |
|
|||||
|
C00020220
|
7-Methoxy-8-(3-methoxy-3-methyl-1-butenyl)flavanone
|
No. 1115 |
|
|||||
|
C00007021
|
O-Methylpongamol
|
No. 1302 |
|
|||||
|
C00007018
|
Pongamol
|
No. 1302 |
|
|||||
|
C00007023
|
Purpuritenin B
|
No. 1302 |
|
|||||
|
C00007022
|
Purpuritenin A
|
No. 1302 |
|
|||||
|
C00004010
|
Lanceolatin A(flavonoid)
|
No. 1381 |
|
|||||
|
C00008373
|
Purpurin (flavanone)
|
No. 2482 |
|
|||||
|
C00014301
|
Tephrorin A
/ (+)-Tephrorin A |
No. 2482 |
|
|||||
|
C00014440
|
(+)-Tephrosone
/ 3-Phenyl-1-[(3S,3aS,8aR)-2,3,3a,8a-tetrahydro-3,4-dihydroxy-2,2-dimethylfuro[2,3-b]benzofuran-5-yl]-2-propen-1-one |
No. 3180 |
|
|||||
|
C00014446
|
(+)-Tephropurpurin
|
CHEMBL457943
|
No. 3180 |
|
||||
|
C00019319
|
7-Acetoxy-2'-methoxy-8-methylisoflavone
|
No. 4241 |
|
|||||
|
C00019320
|
7,2'-Dimethoxy-8-methylisoflavone
|
No. 4241 |
|
Human Protein / Gene in interactions
91 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000615 C00002522 C00002546 C00003672 C00005089 C00007029 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000615 C00002522 C00003672 C00005089 C00007029 | 1 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000615 C00002522 C00003672 C00005089 C00007029 | 0 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000615 C00002522 C00003672 C00005089 C00007029 | 1 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000615 C00002522 C00003672 C00005089 | 3 / 2 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000615 C00003672 C00005089 C00019016 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000615 C00002522 C00005089 C00007029 | 4 / 3 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000615 C00002522 C00003672 C00007029 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00000615 C00003672 | 1 / 1 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00002547 C00005089 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000615 C00002522 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000615 C00005089 | 2 / 2 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000615 C00005089 | 3 / 3 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00000615 C00005089 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00000615 C00003672 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000615 C00005089 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00000615 C00003672 | 4 / 2 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000615 C00005089 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000615 C00005089 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000615 C00003672 | 1 / 1 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00003672 C00003749 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00000615 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000615 | 11 / 10 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00000615 | 2 / 2 |
| Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | Tyr | C00000615 | 4 / 2 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000615 | 1 / 1 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00000615 | 3 / 1 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000615 | 1 / 2 |
| P51452 | Dual specificity protein phosphatase 3 | Ser_Thr_Tyr | C00000615 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00003672 | 1 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00000615 | 0 / 0 |
| Q9GZT9 | Egl nine homolog 1 | Enzyme | C00000615 | 1 / 1 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000615 | 1 / 8 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00003749 | 0 / 0 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00003749 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000615 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00000615 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000615 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000615 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00000615 | 1 / 2 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00000615 | 0 / 0 |
| P42330 | Aldo-keto reductase family 1 member C3 | Enzyme | C00000615 | 0 / 0 |
| Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00000615 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00002547 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00000615 | 0 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00000615 | 0 / 0 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00003672 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00005089 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00000615 | 0 / 1 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00005089 | 7 / 3 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00005089 | 0 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00002522 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00002522 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00003672 | 4 / 2 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000615 | 0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00000615 | 1 / 1 |
| P35236 | Tyrosine-protein phosphatase non-receptor type 7 | Tyr | C00000615 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00000615 | 1 / 1 |
| Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00000615 | 3 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00000615 | 0 / 1 |
| P08253 | 72 kDa type IV collagenase | M10A | C00000615 | 1 / 3 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00000615 | 2 / 2 |
| Q04828 | Aldo-keto reductase family 1 member C1 | Enzyme | C00000615 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000615 | 0 / 3 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00000615 | 5 / 2 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00005089 | 0 / 0 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00000615 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00005089 | 0 / 0 |
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00000615 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003672 | 2 / 0 |
| P52895 | Aldo-keto reductase family 1 member C2 | Enzyme | C00000615 | 1 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00000615 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00000615 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00002522 | 4 / 1 |
| P17516 | Aldo-keto reductase family 1 member C4 | Enzyme | C00000615 | 1 / 0 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00000615 | 0 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00000615 | 1 / 1 |
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00003672 | 1 / 1 |
| Q12794 | Hyaluronidase-1 | Enzyme | C00000615 | 1 / 2 |
| P31639 | Sodium/glucose cotransporter 2 | Glucose | C00002546 | 1 / 1 |
| P24298 | Alanine aminotransferase 1 | Enzyme | C00000615 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002522 | 7 / 37 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000615 | 0 / 0 |
| P13866 | Sodium/glucose cotransporter 1 | Glucose | C00002546 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00000615 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000615 | 1 / 2 |
| P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | C00000615 | 0 / 0 |
| P08238 | Heat shock protein HSP 90-beta | Other cytosolic protein | C00000615 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00000615 | 0 / 0 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00005089 | 0 / 3 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00002547 | 1 / 1 |
87 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa |
C00002522
C00003749
|
| 6194 | RPS6, S6 | ribosomal protein S6 |
C00002522
|
| 133 | ADM, AM | adrenomedullin |
C00002522
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00002522
|
| 51129 | ANGPTL4, ANGPTL2, ARP4, FIAF, HARP, HFARP, NL2, PGAR, UNQ171, pp1158 | angiopoietin-like 4 |
C00002522
|
| 472 | ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1 | ataxia telangiectasia mutated (EC:2.7.11.1) |
C00002522
|
| 545 | ATR, FCTCS, FRP1, MEC1, SCKL, SCKL1 | ataxia telangiectasia and Rad3 related (EC:2.7.11.1) |
C00002522
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00002522
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00002522
|
| 332 | BIRC5, API4, EPR-1 | baculoviral IAP repeat containing 5 |
C00002522
|
| 672 | BRCA1, BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PPP1R53, PSCP, RNF53 | breast cancer 1, early onset |
C00002522
|
| 768 | CA9, CAIX, MN | carbonic anhydrase IX (EC:4.2.1.1) |
C00002522
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00002522
|
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00002522
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00002522
|
| 1001 | CDH3, CDHP, HJMD, PCAD | cadherin 3, type 1, P-cadherin (placental) |
C00002522
|
| 1005 | CDH7, CDH7L1 | cadherin 7, type 2 |
C00002522
|
| 1007 | CDH9 | cadherin 9, type 2 (T1-cadherin) |
C00002522
|
| 1019 | CDK4, CMM3, PSK-J3 | cyclin-dependent kinase 4 (EC:2.7.11.22) |
C00002522
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00002522
|
| 8837 | CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS | CASP8 and FADD-like apoptosis regulator |
C00002522
|
| 9075 | CLDN2 | claudin 2 |
C00002522
|
| 7122 | CLDN5, AWAL, BEC1, CPETRL1, TMVCF | claudin 5 |
C00002522
|
| 7852 | CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM | chemokine (C-X-C motif) receptor 4 |
C00002522
|
| 27123 | DKK2, DKK-2 | dickkopf WNT signaling pathway inhibitor 2 |
C00002522
|
| 27121 | DKK4, DKK-4 | dickkopf WNT signaling pathway inhibitor 4 |
C00002522
|
| 1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00002522
|
| 112399 | EGLN3, HIFP4H3, HIFPH3, PHD3 | egl-9 family hypoxia-inducible factor 3 (EC:1.14.11.29) |
C00002522
|
| 1978 | EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I | eukaryotic translation initiation factor 4E binding protein 1 |
C00002522
|
| 2034 | EPAS1, ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73 | endothelial PAS domain protein 1 |
C00002522
|
| 2487 | FRZB, FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, OS1, SFRP3, SRFP3, hFIZ | frizzled-related protein |
C00002522
|
| 11211 | FZD10, CD350, FZ-10, Fz10, FzE7, hFz10 | frizzled family receptor 10 |
C00002522
|
| 8322 | FZD4, CD344, EVR1, FEVR, FZD4S, Fz-4, Fz4, FzE4, GPCR, hFz4 | frizzled family receptor 4 |
C00002522
|
| 8325 | FZD8, FZ-8, hFZ8 | frizzled family receptor 8 |
C00002522
|
| 2932 | GSK3B | glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) |
C00002522
|
| 3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00002522
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00002522
|
| 3479 | IGF1, IGF-I, IGF1A, IGFI | insulin-like growth factor 1 (somatomedin C) |
C00002522
|
| 3480 | IGF1R, CD221, IGFIR, IGFR, JTK13 | insulin-like growth factor 1 receptor (EC:2.7.10.1) |
C00002522
|
| 3549 | IHH, BDA1, HHG2 | indian hedgehog |
C00002522
|
| 3586 | IL10, CSIF, GVHDS, IL-10, IL10A, TGIF | interleukin 10 |
C00002522
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00002522
|
| 3791 | KDR, CD309, FLK1, VEGFR, VEGFR2 | kinase insert domain receptor (a type III receptor tyrosine kinase) (EC:2.7.10.1) |
C00002522
|
| 4015 | LOX | lysyl oxidase (EC:1.4.3.13) |
C00002522
|
| 5604 | MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1 | mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) |
C00002522
|
| 5605 | MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2 | mitogen-activated protein kinase kinase 2 (EC:2.7.12.2) |
C00002522
|
| 4170 | MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT | myeloid cell leukemia sequence 1 (BCL2-related) |
C00002522
|
| 4255 | MGMT | O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63) |
C00002522
|
| 4288 | MKI67, KIA, MIB-1 | marker of proliferation Ki-67 |
C00002522
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00002522
|
| 2475 | MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1 | mechanistic target of rapamycin (serine/threonine kinase) (EC:2.7.11.1) |
C00002522
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00002522
|
| 8202 | NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP | nuclear receptor coactivator 3 (EC:2.3.1.48) |
C00002522
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00002522
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00002522
|
| 4928 | NUP98, ADIR2, NUP196, NUP96 | nucleoporin 98kDa |
C00002522
|
| 4953 | ODC1, ODC | ornithine decarboxylase 1 (EC:4.1.1.17) |
C00002522
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00002522
|
| 5163 | PDK1 | pyruvate dehydrogenase kinase, isozyme 1 (EC:2.7.11.2) |
C00002522
|
| 5290 | PIK3CA, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (EC:2.7.11.1 2.7.1.153) |
C00002522
|
| 5591 | PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 | protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) |
C00002522
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00002522
|
| 5925 | RB1, OSRC, RB, p105-Rb, pRb, pp110 | retinoblastoma 1 |
C00002522
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002522
|
| 5728 | PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 | phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) |
C00003749
|
| 6198 | RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70_S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha | ribosomal protein S6 kinase, 70kDa, polypeptide 1 (EC:2.7.11.1) |
C00002522
|
| 6423 | SFRP2, FRP-2, SARP1, SDF-5 | secreted frizzled-related protein 2 |
C00002522
|
| 6615 | SNAI1, SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1 | snail family zinc finger 1 |
C00002522
|
| 8403 | SOX14, SOX28 | SRY (sex determining region Y)-box 14 |
C00002522
|
| 11063 | SOX30 | SRY (sex determining region Y)-box 30 |
C00002522
|
| 6660 | SOX5, L-SOX5 | SRY (sex determining region Y)-box 5 |
C00002522
|
| 6714 | SRC, ASV, SRC1, c-SRC, p60-Src | v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (EC:2.7.10.2) |
C00002522
|
| 6774 | STAT3, APRF, HIES | signal transducer and activator of transcription 3 (acute-phase response factor) |
C00002522
|
| 6778 | STAT6, D12S1644, IL-4-STAT, STAT6B, STAT6C | signal transducer and activator of transcription 6, interleukin-4 induced |
C00002522
|
| 412 | STS, ARSC, ARSC1, ASC, ES, SSDD, XLI | steroid sulfatase (microsomal), isozyme S (EC:3.1.6.2) |
C00002522
|
| 6925 | TCF4, E2-2, ITF-2, ITF2, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, TCF-4, bHLHb19 | transcription factor 4 |
C00002522
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00002522
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00002522
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00002522
|
| 11197 | WIF1, WIF-1 | WNT inhibitory factor 1 |
C00002522
|
| 80326 | WNT10A, OODD, SSPS, STHAG4 | wingless-type MMTV integration site family, member 10A |
C00002522
|
| 7481 | WNT11, HWNT11 | wingless-type MMTV integration site family, member 11 |
C00002522
|
| 7222233 |
C00002522
|
||
| 7472 | WNT2, INT1L1, IRP | wingless-type MMTV integration site family member 2 |
C00002522
|
| 7482 | WNT2B, WNT13, XWNT2 | wingless-type MMTV integration site family, member 2B |
C00002522
|
| 89780 | WNT3A | wingless-type MMTV integration site family, member 3A |
C00002522
|
| 331 | XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | X-linked inhibitor of apoptosis |
C00002522
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (92)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #614279 | 46,xy sex reversal 8; srxy8 |
P17516
P52895 |
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #218030 | Apparent mineralocorticoid excess; ame |
P80365
|
| #600807 | Asthma, susceptibility to |
Q13093
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #609820 | Erythrocytosis, familial, 3; ecyt3 |
Q9GZT9
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #606824 | Glucose/galactose malabsorption; ggm |
P13866
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #147050 | Ige responsiveness, atopic; iger |
Q13093
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #607785 | Juvenile myelomonocytic leukemia; jmml |
Q06124
|
| #151100 | Leopard syndrome 1 |
Q06124
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04637 |
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #156250 | Metachondromatosis; metcds |
Q06124
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #601492 | Mucopolysaccharidosis, type ix; mps9 |
Q12794
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #163950 | Noonan syndrome 1; ns1 |
Q06124
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #233100 | Renal glucosuria; glys1 |
P31639
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601367 | Stroke, ischemic |
P00734
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #278300 | Xanthinuria, type i |
P47989
|
KEGG DISEASE (97)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04637 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04637 (related) P08253 (related) |
| H00030 | Cervical cancer |
P00533
(related)
|
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
P16473 (related) |
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P08253 (related) P14780 (related) P35354 (related) |
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
P14679 (marker) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
P35354 (related) |
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01261 | Congenital glucose-galactose malabsorption (GGM) |
P13866
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01126 | Familial renal glucosuria (FRG) |
P31639
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00523 | Noonan syndrome and related disorders |
Q06124
(related)
|
| H01018 | Metachondromatosis |
Q06124
(related)
|
| H00133 | Mucopolysaccharidosis type IX (MPS9) |
Q12794
(related)
|
| H00421 | Mucopolysaccharidosis (MPS) |
Q12794
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00236 | Congenital polycythemia |
Q9GZT9
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
Diseases related to CTD interactions
13 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D006528 | Carcinoma, Hepatocellular |
C00003749
C00002522 |
| D012878 | Skin Neoplasms |
C00003749
C00002522 |
| D009374 | Neoplasms, Experimental |
C00003749
C00002522 |
| D001943 | Breast Neoplasms |
C00002522
|
| D009202 | Cardiomyopathies |
C00003749
|
| D014947 | Wounds and Injuries |
C00003749
|
| D006937 | Hypercholesterolemia |
C00003749
|
| D008175 | Lung Neoplasms |
C00002522
|
| D008207 | Lymphatic Metastasis |
C00002522
|
| D009361 | Neoplasm Invasiveness |
C00002522
|
| D009362 | Neoplasm Metastasis |
C00002522
|
| D009369 | Neoplasms |
C00002522
|
| D011471 | Prostatic Neoplasms |
C00002522
|