Species

KNApSAcK Entry

Organism name Eucommia ulmoides
Genus Eucommia
Family Eucommiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Eucommia ulmoides
Linked NCBI taxonomy ID 4392
Linked level species

Family

Family in NCBI taxonomy Eucommiaceae
ID 4390

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (16)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005392 External link 512 Quercetin 3-glucosyl-(1->2)-xyloside
No. 1 No. 15
C00007190 External link 512 (+)-Pinoresinol
CHEMBL267963
CHEMBL487611
CHEMBL460862
C103298
7 / 5 / 6 No. 38 No. 21
C00007192 External link 512 (+)-Epipinoresinol
CHEMBL267963
CHEMBL487611
CHEMBL460862
7 / 5 / 6 No. 38 No. 21
C00000659 External link 512 Medioresinol
/ (+)-Medioresinol
CHEMBL376507
CHEMBL513023
2 / 1 / 1 No. 38 No. 21
C00002631 External link 512 (+)-Lirioresinol B
/ (+)-Syringaresinol
CHEMBL361362
CHEMBL402653
C042192
1 / 0 / 0 No. 38 No. 21
C00000724 External link 512 (+)-Hydroxypinoresinol 4,4'-di-O-beta-D-glucopyranoside
No. 152
C00000723 External link 512 Liriodendrin
/ Acanthoside D
/ (+)-Syringaresinol di-O-beta-glucopyranoside
CHEMBL446836
CHEMBL505393
2 / 2 / 2 No. 152
C00002601 External link 512 Eucommin A
CHEMBL573786
CHEMBL1076999
No. 174 No. 22
C00002632 External link 512 Acanthoside B
/ Eleutheroside E1
/ (+)-Syringaresinol O-beta-D-glucoside
/ (+)-Syringaresinol 4'-O-beta-glucopyranoside
/ (+)-Syringaresinol-4-O-beta-D-glucopyranoside
CHEMBL573710
CHEMBL1077080
C087806
No. 174 No. 22
C00000672 External link 512 Dihydrodehydrodiconiferyl alcohol
CHEMBL261907
CHEMBL253590
No. 215 No. 23
C00010498 External link 512 Ulmoside
No. 222
C00007206 External link 512 (+)-Cycloolivil
CHEMBL516536
1 / 1 / 1 No. 406
C00000683 External link 512 Hedyotol C
CHEMBL1761717
No. 428
C00007191 External link 512 (+)-8(1)-Hydroxypinoresinol
CHEMBL471274
No. 700 No. 21
C00000682 External link 512 (-)-Olivil
/ Vladinol C
CHEMBL517144
1 / 1 / 1 No. 700 No. 21
C00010806 External link 512 Eucommiol
No. 5634

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00007190 C00007192 0 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00007190 C00007192 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00007190 C00007192 0 / 3
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00007190 C00007192 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00000682 C00007206 1 / 1
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00007190 C00007192 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00007190 C00007192 0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00007190 C00007192 5 / 3
P17405 Sphingomyelin phosphodiesterase Enzyme C00000723 2 / 2
O75496 Geminin Unclassified protein C00000723 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000659 0 / 1
P11387 DNA topoisomerase 1 Isomerase C00002631 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000659 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#608902 Drug metabolism, poor, cyp2d6-related P10635
#137800 Glioma susceptibility 1; glm1 P37231
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#601665 Obesity P37231
#278300 Xanthinuria, type i P47989

KEGG DISEASE (10)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00192 Xanthinuria P47989 (related)