Species

KNApSAcK Entry

Organism name Strychnos axillaris
Genus Strychnos
Family Longaniaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Strychnos axillaris
Linked NCBI taxonomy ID 1037789
Linked level species

Family

Family in NCBI taxonomy Loganiaceae
ID 26468

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (18)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005655 External link 512 Axillaroside
/ Axillarin 7-glucoside
No. 2 No. 15
C00019029 External link 512 Tachioside
/ 3-Methoxy-4-hydroxyphenyl-beta-D-glucopyranoside
CHEMBL1077078
No. 45 No. 72
C00019030 External link 512 Isotachioside
/ Methoxy-hydroquinone-1-O-beta-D-glucopyranoside
/ 4-Hydroxy-2-methoxyphenyl-beta-D-Glucopyranoside
No. 45 No. 72
C00032471 External link 512 Vanilloloside
CHEMBL468568
1 / 0 / 3 No. 45 No. 72
C00033688 External link 512 Calleryanin
No. 45 No. 72
C00003088 External link 512 Loganin
CHEMBL1081584
CHEMBL1081586
CHEMBL1589904
CHEMBL2135791
C059516
2 / 1 / 1 0 / 1 No. 56 No. 36
C00010604 External link 512 Loganic acid
CHEMBL1081585
CHEMBL1079678
CHEMBL1356464
CHEMBL1452775
C002947
6 / 8 / 7 No. 64 No. 36
C00000723 External link 512 Liriodendrin
/ Acanthoside D
/ (+)-Syringaresinol di-O-beta-glucopyranoside
CHEMBL446836
CHEMBL505393
2 / 2 / 2 No. 152
C00002632 External link 512 Acanthoside B
/ Eleutheroside E1
/ (+)-Syringaresinol O-beta-D-glucoside
/ (+)-Syringaresinol 4'-O-beta-glucopyranoside
/ (+)-Syringaresinol-4-O-beta-D-glucopyranoside
CHEMBL573710
CHEMBL1077080
C087806
No. 174 No. 22
C00031451 External link 512 (-)-Pinoresinol O-beta-D-glucopyranoside
/ (-)-Pinoresinol 4-O-beta-D-glucopyranoside
CHEMBL573336
CHEMBL1083218
CHEMBL1302893
9 / 6 / 4 No. 174 No. 22
C00034222 External link 512 Scorzonoside
/ (-)-Scorzonoside
No. 193
C00010743 External link 512 Cantleyoside
No. 284
C00032424 External link 512 Triplostoside A
No. 284
C00033684 External link 512 Caffeoylcalleryanin
No. 382
C00033559 External link 512 3,5-Caffeoyl quinic acid
/ 3,5-di-O-Caffeoylquinic acid
/ (-)-3,5-Dicaffeoyl quinic acid
CHEMBL441250
CHEMBL249447
2 / 0 / 0 No. 518 No. 6
C00029480 External link 512 3,4-di-O-Caffeoylquinic acid
/ (-)-4,5-Dicaffeoyl quinic acid
CHEMBL358821
CHEMBL149674
CHEMBL177126
CHEMBL249448
CHEMBL453276
CHEMBL453537
CHEMBL1972460
2 / 0 / 0 No. 518 No. 6
C00034294 External link 512 Strictosidinic acid
CHEMBL528546
No. 618 No. 4
C00010794 External link 512 Sweroside
CHEMBL456137
C049412
1 / 0 / 0 No. 806 No. 36

Human Protein / Gene in interactions

21 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O60218 Aldo-keto reductase family 1 member B10 Enzyme C00029480 C00033559 0 / 0
P15121 Aldose reductase Enzyme C00029480 C00033559 0 / 0
O75496 Geminin Unclassified protein C00000723 C00003088 0 / 0
P60033 CD81 antigen Unclassified protein C00003088 C00010604 1 / 1
Q9Y253 DNA polymerase eta Enzyme C00031451 1 / 1
P10253 Lysosomal alpha-glucosidase Hydrolase C00031451 1 / 1
P17405 Sphingomyelin phosphodiesterase Enzyme C00000723 2 / 2
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00010604 2 / 0
P06746 DNA polymerase beta Enzyme C00031451 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00032471 0 / 3
P37840 Alpha-synuclein Unclassified protein C00031451 4 / 2
Q9UNA4 DNA polymerase iota Enzyme C00031451 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00010604 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00010604 0 / 0
P07900 Heat shock protein HSP 90-alpha Other cytosolic protein C00010794 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00031451 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00031451 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00031451 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00010604 1 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00031451 0 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00010604 0 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (16)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P84022
#127750 Dementia, lewy body; dlb P37840
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#232300 Glycogen storage disease ii P10253
#613496 Immunodeficiency, common variable, 6; cvid6 P60033
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (16)

KEGG name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00088 Common variable immunodeficiency (CVID) P60033 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D008569 Memory Disorders C00003088