Species

KNApSAcK Entry

Organism name Boesenbergia rotunda (L.) Mansf.Kulturpfl.
Genus Boesenbergia
Family Zingiberaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Boesenbergia
Linked NCBI taxonomy ID 97724
Linked level genus

Family

Family in NCBI taxonomy Zingiberaceae
ID 4642

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (9)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000999 External link 512 Sakuranetin
/ Naringenin 7-O-methyl ether
/ 5,4'-Dihydroxy-7-methoxyflavanone
CHEMBL74852
CHEMBL448297
C099724
19 / 20 / 20 No. 25 No. 14
C00036493 External link 512 2'-Hydroxy-4,4',6'-trimethoxychalcone
CHEMBL243829
3 / 3 / 0 No. 79
C00006934 External link 512 Pinostrobin chalcone
/ 2',6'-Dihydroxy-4'-methoxychalcone
CHEMBL317221
CHEMBL1705800
3 / 1 / 2 No. 92 No. 13
C00007131 External link 512 Boesenbergin A
CHEMBL442440
No. 186
C00003444 External link 512 miropinic acid
/ Isopimaric acid
/ isodextropimaric acid
CHEMBL512164
C115138
3 / 1 / 1 No. 208 No. 48
C00036322 External link 512 (+)-Zeylenol
No. 2680
C00036823 External link 512 Boesenboxide
/ (+)-Boesenboxide
No. 3545
C00036940 External link 512 Crotepoxide
/ (+)-Crotepoxide
CHEMBL1976475
C011828
No. 3545
C00007133 External link 512 Rubranine
No. 4362

Human Protein / Gene in interactions

28 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P33527 Multidrug resistance-associated protein 1 drugs C00036493 0 / 0
Q99700 Ataxin-2 Unclassified protein C00000999 1 / 1
P33765 Adenosine receptor A3 Adenosine receptor C00000999 0 / 0
P04062 Glucosylceramidase Enzyme C00000999 6 / 4
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00000999 0 / 0
Q13315 Serine-protein kinase ATM Atypical serine/threonine protein kinase PIKK subfamily C00000999 1 / 4
P08183 Multidrug resistance protein 1 drug C00036493 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00006934 0 / 1
P47870 Gamma-aminobutyric acid receptor subunit beta-2 GABA-A beta C00003444 0 / 0
P14867 Gamma-aminobutyric acid receptor subunit alpha-1 GABA-A alpha C00003444 1 / 1
P11473 Vitamin D3 receptor NR1I1 C00000999 2 / 3
Q9Y3R4 Sialidase-2 Enzyme C00000999 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00000999 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00003444 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00000999 2 / 0
O75496 Geminin Unclassified protein C00000999 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00000999 1 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00000999 0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00036493 2 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00000999 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00006934 1 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00006934 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00000999 4 / 3
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00000999 1 / 1
P59538 Taste receptor type 2 member 31 Taste receptor (taste family GPCR) C00000999 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00000999 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00000999 1 / 4
Q13148 TAR DNA-binding protein 43 Unclassified protein C00000999 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (25)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#208900 Ataxia-telangiectasia; at Q13315
#614490 Blood group, junior system; jr Q9UNQ0
#114500 Colorectal cancer; crc P84022
#609535 Drug metabolism, poor, cyp2c19-related P33261
#611136 Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 P14867
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#612244 Inflammatory bowel disease 13; ibd13 P08183
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (23)

KEGG name UniProt
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00808 Idiopathic generalized epilepsies (IGEs) P14867 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) Q13315 (related)
H00064 Ataxia telangiectasia (AT) Q13315 (related)
H00094 DNA repair defects Q13315 (related)
H00848 Ataxia with ocular apraxia (AOA) Q13315 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)