Kaempferia parviflora
Species
KNApSAcK Entry
| Organism name | Kaempferia parviflora |
|---|---|
| Genus | Kaempferia |
| Family | Zingiberaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Kaempferia parviflora |
|---|---|
| Linked NCBI taxonomy ID | 97751 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Zingiberaceae |
|---|---|
| ID | 4642 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Liliopsida |
|---|---|
| ID | 4447 |
Metabolite list (16)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00001016
|
7-O-Methylacacetin
/ Acacetin 7-methyl ether / Genkwanin 4'-methyl ether / Apigenin 7,4'-dimethyl ether / 5-Hydroxy-4',7-dimethoxyflavone / 5-Hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL350958
|
C044998
|
1 / 0 / 0 | No. 3 | No. 15 |
|
|
|
C00004647
|
Ayanin
/ 3,7,4'-Tri-O-methylquercetin / 5,3'-Dihydroxy-3,7,4'-trimethoxyflavone / 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL74898
|
18 / 10 / 2 | No. 3 | No. 15 |
|
||
|
C00033568
|
4'-Hydroxy-5,7-dimethoxyflavone
|
C054244
|
No. 3 | No. 15 |
|
|||
|
C00013350
|
Tetramethylkaempferol
/ O-Tetramethylkaempferol / 3,5,7,4'-Tetramethoxyflavone / 2-(4-Methoxyphenyl)-3,5,7-trimethoxy-4-oxo-4H-1-benzopyran / 3,5,7-Trimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL356036
|
1 / 0 / 0 | No. 8 | No. 15 |
|
||
|
C00003871
|
5,7,3',4'-Tetramethoxyflavone
/ Luteolin 5,7,3',4'-tetramethyl ether |
CHEMBL327340
|
C103111
|
1 / 0 | No. 8 | No. 15 |
|
|
|
C00004655
|
Quercetin pentamethyl ether
/ 3,5,7,3',4'-Pentamethoxyflavone |
CHEMBL19032
|
16 / 10 / 12 | No. 8 | No. 15 |
|
||
|
C00003821
|
5,7,4'-Trimethoxyflavone
/ Apigenin 5,7,4'-trimethyl ether |
CHEMBL1087720
|
C103112
|
1 / 1 / 0 | 1 / 0 | No. 35 | No. 15 |
|
|
C00004537
|
3,7-Dimethylgalangin
/ Galangin 3,7-dimethyl ether / 3,7-Dimethoxy-5-hydroxyflavone / 5-Hydroxy-3,7-dimethoxy-2-phenyl-4H-1-benzopyran-4-one |
CHEMBL1097683
|
No. 35 | No. 15 |
|
|||
|
C00001042
|
3,5,7-trimethoxyflavone
/ Galangin trimethyl ether / Galangin 3,5,7-trimethyl ether |
CHEMBL75772
|
1 / 0 / 0 | No. 35 | No. 15 |
|
||
|
C00001028
|
5,7-Dimethoxyflavone
/ chrysin 5,7-dimethyl ether |
CHEMBL275391
|
C060298
|
14 / 13 / 13 | 2 / 3 | No. 35 | No. 15 |
|
|
C00003870
|
Luteolin 7,3',4'-trimethyl ether
/ 5-Hydroxy-7,3',4'-trimethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one |
CHEMBL468876
|
No. 35 | No. 15 |
|
|||
|
C00004573
|
3,7,4'-Tri-O-methylkaempferol
/ Kaempferol 3,7,4'-trimethyl ether / 5-Hydroxy-3,7,4'-trimethoxyflavone / 5-Hydroxy-3,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL77686
|
No. 35 | No. 15 |
|
|||
|
C00003795
|
Tectochrysin
/ 5-hydroxy-7-methoxyflavone |
CHEMBL164841
|
12 / 19 / 14 | No. 76 | No. 15 |
|
||
|
C00033675
|
beta-Sitosteryl myristate
|
No. 1152 |
|
|||||
|
C00030757
|
Methyl linoleate
/ Methyl 9Z,12Z-octadecadienoate |
C005575
|
No. 1785 |
|
||||
|
C00033502
|
(1E,6E)-1,7-Diphenyl-1,6-heptadiene-3,5-dione
|
CHEMBL102914
|
No. 2164 |
|
Human Protein / Gene in interactions
48 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P08183 | Multidrug resistance protein 1 | drug | C00003795 C00003821 C00004647 | 1 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00001016 C00001042 C00013350 | 0 / 0 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00001028 C00004647 C00004655 | 2 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001028 C00003795 C00004655 | 0 / 0 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00004647 C00004655 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003795 C00004655 | 0 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001028 C00004655 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00001028 C00004655 | 2 / 5 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00001028 C00003795 | 1 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001028 C00004655 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001028 C00004655 | 1 / 2 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00001028 C00004655 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001028 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00001028 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00001028 | 4 / 2 |
| P39748 | Flap endonuclease 1 | Enzyme | C00004655 | 0 / 0 |
| Q12791 | Calcium-activated potassium channel subunit alpha-1 | KCNM, KCa1.x | C00004655 | 1 / 1 |
| P51843 | Nuclear receptor subfamily 0 group B member 1 | Nuclear hormone receptor subfamily 0 group B member 1 | C00001028 | 2 / 2 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00004655 | 0 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00004655 | 2 / 2 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00004655 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00003795 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00003795 | 1 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00003795 | 3 / 2 |
| O75496 | Geminin | Unclassified protein | C00003795 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00003795 | 4 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003795 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001028 | 0 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00003795 | 4 / 2 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00004655 | 1 / 1 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00004655 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00003795 | 6 / 4 |
| Q13748 | Tubulin alpha-3C/D chain | Structural | C00004647 | 0 / 0 |
| P68366 | Tubulin alpha-4A chain | Structural | C00004647 | 0 / 0 |
| Q9H4B7 | Tubulin beta-1 chain | Structural | C00004647 | 1 / 0 |
| P04350 | Tubulin beta-4A chain | Structural | C00004647 | 2 / 0 |
| Q3ZCM7 | Tubulin beta-8 chain | Structural | C00004647 | 0 / 0 |
| P07437 | Tubulin beta chain | Structural | C00004647 | 0 / 0 |
| Q71U36 | Tubulin alpha-1A chain | Structural | C00004647 | 1 / 1 |
| P68371 | Tubulin beta-4B chain | Structural | C00004647 | 0 / 0 |
| Q13509 | Tubulin beta-3 chain | Structural | C00004647 | 2 / 1 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00001028 | 1 / 1 |
| P68363 | Tubulin alpha-1B chain | Unclassified protein | C00004647 | 0 / 0 |
| Q13885 | Tubulin beta-2A chain | Structural | C00004647 | 0 / 0 |
| Q6PEY2 | Tubulin alpha-3E chain | Unclassified protein | C00004647 | 0 / 0 |
| Q9BQE3 | Tubulin alpha-1C chain | Unclassified protein | C00004647 | 0 / 0 |
| Q9BUF5 | Tubulin beta-6 chain | Structural | C00004647 | 0 / 0 |
| Q9BVA1 | Tubulin beta-2B chain | Structural | C00004647 | 1 / 0 |
3 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00001028
C00003821
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001028
|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00003871
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (43)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300018 | 46,xy sex reversal 2; srxy2 |
P51843
|
| #300200 | Adrenal hypoplasia, congenital; ahc |
P51843
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #614039 | Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 |
Q13509
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #128101 | Dystonia 4, torsion, autosomal dominant; dyt4 |
P04350
|
| #600638 | Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a |
Q13509
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #609446 | Generalized epilepsy and paroxysmal dyskinesia; gepd |
Q12791
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #612438 | Leukodystrophy, hypomyelinating, 6; hld6 |
P04350
|
| #611603 | Lissencephaly 3; lis3 |
Q71U36
|
| #613112 | Macrothrombocytopenia, autosomal dominant, tubb1-related |
Q9H4B7
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #167000 | Ovarian cancer |
P38398
|
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
P37840 |
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #610031 | Polymicrogyria, symmetric or asymmetric; pmgysa |
Q9BVA1
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
KEGG DISEASE (31)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
P37840 (related) |
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00027 | Ovarian cancer |
P38398
(related)
|
| H00031 | Breast cancer |
P38398
(related)
|
| H00552 | Glycerol kinase deficiency (GKD) |
P51843
(related)
|
| H00607 | 46,XY disorders of sex development (Disorders of gonadal development) |
P51843
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H01258 | Generalized epilepsy and paroxysmal dyskinesia (GEPD) |
Q12791
(related)
|
| H00838 | Congenital fibrosis of the extraocular muscles (CFEOM) |
Q13509
(related)
|
| H00268 | Lissencephaly (LIS) |
Q71U36
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|