KNApSAcK Entry

Organism name Scutellaria baicalensis
Genus Scutellaria
Family Labiatae
Kingdom Plantae

NCBI taxonomy


Linked NCBI taxonomy name Scutellaria baicalensis
Linked NCBI taxonomy ID 65409
Linked level species


Family in NCBI taxonomy Lamiaceae
ID 4136

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (37)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
C00006182 External link 512 Chrysin 6-C-alpha-L-arabinopyranoside-8-C-glucoside
C00006181 External link 512 Chrysin 6-C-glucoside-8-C-alpha-L-arabinopyranoside
No. 1 No. 15
C00013727 External link 512 5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone 2'-glucoside
/ 2-[2-(beta-D-Glucopyranosyloxy)-6-hydroxyphenyl]-5-hydroxy-6,7,8-trimethoxy-4H-1-benzopyran-4-one
No. 2 No. 15
C00001024 External link 512 Baicalin
/ Baicalein 7-glucuronide
41 / 22 / 18 9 / 7 No. 2 No. 15
C00004530 External link 512 5,7,3',6'-Tetrahydroxy-8,2'-dimethoxyflavone 6'-glucoside
No. 2 No. 15
C00013651 External link 512 5,7,2',6'-Tetrahydroxyflavone 2'-O-glucoside
/ 2-[2-(beta-D-Glucopyranosyloxy)-6-hydroxyphenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one
No. 2 No. 15
C00004130 External link 512 Wogonin 7-glucoside
/ Wogonin-7-O-glucuronide
No. 2 No. 15
C00004129 External link 512 Wogonin 5-glucoside
No. 2 No. 15
C00013710 External link 512 5,2',6'-Trihydroxy-6,7-dimethoxyflavone 2'-glucoside
/ 2-[2-(beta-D-Glucopyranosyloxy)-6-hydroxyphenyl]-5-hydroxy-6,7-dimethoxy-4H-1-benzopyran-4-one
No. 2 No. 15
C00003851 External link 512 Takakin
/ 5,7,8-Trihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
No. 3 No. 15
C00003863 External link 512 5,7,2'-Trihydroxy-6'-methoxyflavone
No. 3 No. 15
C00003874 External link 512 5,8,2'-Trihydroxy-6,7-dimethoxyflavone
No. 3 No. 15
C00003903 External link 512 5,7,2'-Trihydroxy-8,6'-dimethoxyflavone
No. 3 No. 15
C00003844 External link 512 Skullcapflavone I
/ 5-Hydroxy-2-(2-hydroxyphenyl)-7,8-dimethoxy-4H-1-benzopyran-4-one
No. 3 No. 15
C00003922 External link 512 5,2',5'-Trihydroxy-6,7,8-trimethoxyflavone
No. 3 No. 15
C00003955 External link 512 5,7,2',3'-Tetrahydroxy-8,6'-dimethoxyflavone
No. 3 No. 15
C00003842 External link 512 5,8,2'-Trihydroxy-7-methoxyflavone
No. 3 No. 15
C00004746 External link 512 Viscidulin III
No. 3 No. 15
C00003829 External link 512 5,8-Dihydroxy-6,7-dimethoxyflavone
/ 5,8-Dihydroxy-6,7-dimethoxy-2-phenyl-4H-1-benzopyran-4-one
No. 3 No. 15
C00004627 External link 512 3,5,7,2',5'-Pentahydroxyflavone
No. 3 No. 15
C00004629 External link 512 Viscidulin I
No. 3 No. 15
C00003904 External link 512 Rivularin (flavone)
/ 5-Hydroxy-2-(2-hydroxy-6-methoxyphenyl)-7,8-dimethoxy-4H-1-benzopyran-4-one
No. 3 No. 15
C00003833 External link 512 5,7,2'-Trihydroxy-6-methoxyflavone
No. 3 No. 15
C00004630 External link 512 3,5,7,2',6'-Pentamethoxyflavone
No. 8 No. 15
C00001099 External link 512 Neobaicalein
/ Skullcapflavone II
No. 8 No. 15
C00014011 External link 512 Chrysin 8-C-glucopyranoside
/ Chrysin 8-C-beta-D-glucopyranoside
/ 8-beta-D-Glucopyranosyl-5,7-dihydroxy-2-phenyl-4H-1-benzopyran-4-one
No. 22 No. 15
C00014012 External link 512 Chrysin 6-C-glucopyranoside
/ Chrysin 6-C-beta-D-glucopyranoside
/ 6-beta-D-Glucopyranosyl-5,7-dihydroxy-2-phenyl-4H-1-benzopyran-4-one
No. 22 No. 15
C00008233 External link 512 5,7,4'-Trihydroxy-6-methoxyflavanone
No. 25 No. 14
C00008339 External link 512 7,2',6'-Trihydroxy-5-methoxyflavanone
No. 25 No. 14
C00008230 External link 512 Carthamidin
No. 25 No. 14
C00008232 External link 512 Isocarthamidin
No. 25 No. 14
C00002631 External link 512 (+)-Lirioresinol B
/ (+)-Syringaresinol
1 / 0 / 0 No. 38 No. 21
C00008574 External link 512 3,5,7,2',6'-Pentahydroxyflavanone
No. 42 No. 14
C00013305 External link 512 5,7,2',5'-Tetrahydroxyflavone
/ 2-(2,5-Dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
No. 71 No. 15
C00013561 External link 512 5,7,2',3'-Tetrahydroxyflavone
/ 2-(2,3-Dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
No. 71 No. 15
C00003815 External link 512 5,7,2'-Trihydroxyflavone
10 / 16 / 48 No. 71 No. 15
C00001022 External link 512 Baicalein
/ Noroxylin
/ 5,6,7-Trihydroxyflavone
83 / 77 / 82 39 / 8 No. 76 No. 15

Human Protein / Gene in interactions

92 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001022 C00001024 C00003815 1 / 2
P10636 Microtubule-associated protein tau Unclassified protein C00001022 C00001024 C00003815 4 / 3
O00255 Menin Unclassified protein C00001022 C00001024 C00003815 2 / 5
P14867 Gamma-aminobutyric acid receptor subunit alpha-1 GABA-A alpha C00001022 C00001024 1 / 1
P18505 Gamma-aminobutyric acid receptor subunit beta-1 GABA-A beta C00001022 C00001024 0 / 0
P18507 Gamma-aminobutyric acid receptor subunit gamma-2 GABA-A gamma C00001022 C00001024 4 / 2
P47870 Gamma-aminobutyric acid receptor subunit beta-2 GABA-A beta C00001022 C00001024 0 / 0
O00591 Gamma-aminobutyric acid receptor subunit pi GABA-A pi C00001022 C00001024 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00001022 C00001024 1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001022 C00001024 0 / 0
P34903 Gamma-aminobutyric acid receptor subunit alpha-3 GABA-A alpha C00001022 C00001024 0 / 0
Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 GABA-A gamma C00001022 C00001024 0 / 0
P78334 Gamma-aminobutyric acid receptor subunit epsilon GABA-A epsilon C00001022 C00001024 0 / 0
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00001022 C00001024 0 / 0
Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 GABA-A gamma C00001022 C00001024 0 / 0
P31644 Gamma-aminobutyric acid receptor subunit alpha-5 GABA-A alpha C00001022 C00001024 0 / 0
O14764 Gamma-aminobutyric acid receptor subunit delta GABA-A delta C00001022 C00001024 1 / 1
P06493 Cyclin-dependent kinase 1 Cdc2 C00001022 C00001024 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001022 C00003815 0 / 1
P48169 Gamma-aminobutyric acid receptor subunit alpha-4 GABA-A alpha C00001022 C00001024 0 / 0
Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 GABA-A alpha C00001022 C00001024 0 / 0
P28472 Gamma-aminobutyric acid receptor subunit beta-3 GABA-A beta C00001022 C00001024 1 / 0
Q9UN88 Gamma-aminobutyric acid receptor subunit theta GABA-A theta C00001022 C00001024 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001022 C00003815 1 / 0
P47869 Gamma-aminobutyric acid receptor subunit alpha-2 GABA-A alpha C00001022 C00001024 1 / 0
Q9Y3R4 Sialidase-2 Enzyme C00001022 C00003815 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00001022 C00001024 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00001022 C00001024 0 / 0
P48147 Prolyl endopeptidase S9A C00001022 C00001024 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00001022 C00003815 7 / 37
O75164 Lysine-specific demethylase 4A Enzyme C00001022 C00001024 0 / 0
P39748 Flap endonuclease 1 Enzyme C00001022 C00001024 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00001022 C00001024 0 / 0
O75496 Geminin Unclassified protein C00001022 C00001024 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001022 C00003815 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001022 C00003815 1 / 1
P27487 Dipeptidyl peptidase 4 S9B C00001022 C00001024 0 / 1
P03372 Estrogen receptor NR3A1 C00001022 C00001024 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001022 C00001024 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00001022 C00001024 2 / 2
P46063 ATP-dependent DNA helicase Q1 Enzyme C00001022 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00001022 0 / 1
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00001022 4 / 4
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00001022 2 / 0
P37058 Testosterone 17-beta-dehydrogenase 3 Enzyme C00001022 1 / 1
P28482 Mitogen-activated protein kinase 1 Erk C00003815 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001022 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00001022 3 / 3
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein C00001024 1 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00001022 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00001022 1 / 1
P14410 Sucrase-isomaltase, intestinal Enzyme C00001022 1 / 1
P16050 Arachidonate 15-lipoxygenase Enzyme C00001022 0 / 0
P14151 L-selectin Adhesion C00001022 0 / 0
P16109 P-selectin Adhesion C00001022 1 / 0
P54855 UDP-glucuronosyltransferase 2B15 Enzyme C00001022 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00001022 4 / 2
Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor Enzyme C00001022 0 / 0
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00001022 1 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001022 0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00001022 5 / 1
P68871 Hemoglobin subunit beta Secreted protein C00001022 4 / 4
O43451 Maltase-glucoamylase, intestinal Hydrolase C00001022 0 / 0
P10275 Androgen receptor NR3C4 C00001022 3 / 4
P05412 Transcription factor AP-1 Transcription Factor C00001022 0 / 0
Q04760 Lactoylglutathione lyase Enzyme C00001022 0 / 0
P16581 E-selectin Adhesion C00001022 0 / 0
O15296 Arachidonate 15-lipoxygenase B Enzyme C00001022 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001022 0 / 0
Q9NPD5 Solute carrier organic anion transporter family member 1B3 Electrochemical transporter C00001024 1 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00001024 0 / 0
P11387 DNA topoisomerase 1 Isomerase C00002631 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00001024 1 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00001022 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00001022 1 / 4
Q9HC97 G-protein coupled receptor 35 Kynurenic acid receptor C00001022 0 / 0
P54132 Bloom syndrome protein Enzyme C00001022 1 / 2
Q9GZT9 Egl nine homolog 1 Enzyme C00001022 1 / 1
P16220 Cyclic AMP-responsive element-binding protein 1 Unclassified protein C00001022 1 / 0
P08183 Multidrug resistance protein 1 drug C00001022 1 / 0
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00001022 0 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim C00001022 0 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00001022 3 / 1
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00001022 1 / 1
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00001022 0 / 0
P04062 Glucosylceramidase Enzyme C00001022 6 / 4
P06746 DNA polymerase beta Enzyme C00001024 0 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00001022 0 / 0
O94956 Solute carrier organic anion transporter family member 2B1 Unclassified protein C00001024 0 / 0
Q9Y6L6 Solute carrier organic anion transporter family member 1B1 Electrochemical transporter C00001024 1 / 0
Q16637 Survival motor neuron protein Unclassified protein C00001022 4 / 1
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00001022 2 / 1

39 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
581 BAX, BCL2L4 BCL2-associated X protein C00001022 C00001024
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00001022 C00001024
4851 NOTCH1, TAN1, hN1 notch 1 C00001022 C00001024
23493 HEY2, CHF1, GRIDLOCK, GRL, HERP1, HESR2, HRT2, bHLHb32 hes-related family bHLH transcription factor with YRPW motif 2 C00001022 C00001024
23462 HEY1, BHLHb31, CHF2, HERP2, HESR1, HRT-1, OAF1, hHRT1 hes-related family bHLH transcription factor with YRPW motif 1 C00001022 C00001024
890 CCNA2, CCN1, CCNA cyclin A2 C00001022 C00001024
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00001022 C00001024
3280 HES1, HES-1, HHL, HRY, bHLHb39 hes family bHLH transcription factor 1 C00001022 C00001024
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC: C00001022 C00001024
3291 HSD11B2, AME, AME1, HSD11K, HSD2, SDR9C3 hydroxysteroid (11-beta) dehydrogenase 2 (EC: C00001022
1080 CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC: C00001022
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC: C00001022
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC: C00001022
1559 CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 cytochrome P450, family 2, subfamily C, polypeptide 9 (EC: C00001022
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC: C00001022
2932 GSK3B glycogen synthase kinase 3 beta (EC: C00001022
1019 CDK4, CMM3, PSK-J3 cyclin-dependent kinase 4 (EC: C00001022
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00001022
239 ALOX12, 12-LOX, 12S-LOX, LOG12 arachidonate 12-lipoxygenase (EC: C00001022
1437 CSF2, GMCSF colony stimulating factor 2 (granulocyte-macrophage) C00001022
3630 INS, IDDM2, ILPR, IRDN, MODY10 insulin C00001022
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC: C00001022
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC: C00001022
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC: C00001022
4313 MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC: C00001022
4318 MMP9, CLG4B, GELB, MANDP2, MMP-9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC: C00001022
9 NAT1, AAC1, MNAT, NAT-1, NATI N-acetyltransferase 1 (arylamine N-acetyltransferase) (EC: C00001022
4790 NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 C00001022
4793 NFKBIB, IKBB, TRIP9 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta C00001022
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC: C00001022
5328 PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA plasminogen activator, urokinase (EC: C00001022
5366 PMAIP1, APR, NOXA phorbol-12-myristate-13-acetate-induced protein 1 C00001022
5578 PRKCA, AAG6, PKC-alpha, PKCA, PRKACA protein kinase C, alpha (EC: C00001022
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC: C00001022
5925 RB1, OSRC, RB, p105-Rb, pRb, pp110 retinoblastoma 1 C00001022
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00001022
196 AHR, bHLHe76 aryl hydrocarbon receptor C00001022
7366 UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 UDP glucuronosyltransferase 2 family, polypeptide B15 (EC: C00001022
7422 VEGFA, MVCD1, VEGF, VPF vascular endothelial growth factor A C00001022

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (80)

OMIM preferred title UniProt
#264300 17-beta hydroxysteroid dehydrogenase iii deficiency P37058
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103780 Alcohol dependence P47869
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#613985 Beta-thalassemia P68871
#603902 Beta-thalassemia, dominant inclusion body type P68871
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#210900 Bloom syndrome; blm P54132
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#114500 Colorectal cancer; crc P18054
#218800 Crigler-najjar syndrome, type i P22309
#606785 Crigler-najjar syndrome, type ii P22309
#119900 Digital clubbing, isolated congenital P15428
#607208 Dravet syndrome P18507
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#237500 Dubin-johnson syndrome; djs Q92887
#607681 Epilepsy, childhood absence, susceptibility to, 2; eca2 P18507
#612269 Epilepsy, childhood absence, susceptibility to, 5; eca5 P28472
#613060 Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 O14764
#611136 Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 P14867
#609820 Erythrocytosis, familial, 3; ecyt3 Q9GZT9
#133239 Esophageal cancer P04637
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#604233 Generalized epilepsy with febrile seizures plus, type 1; gefsp1 P18507
#611277 Generalized epilepsy with febrile seizures plus, type 3; gefsp3 P18507
#143500 Gilbert syndrome P22309
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#140700 Heinz body anemias P68871
#612160 Histiocytoma, angiomatoid fibrous P16220
#237450 Hyperbilirubinemia, rotor type; hblrr Q9NPD5
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#612244 Inflammatory bowel disease 13; ibd13 P08183
#601626 Leukemia, acute myeloid; aml P36888
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#211980 Lung cancer P04637
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#604229 Peters anomaly Q16678
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#603903 Sickle cell anemia P68871
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601367 Stroke, ischemic P16109
#222900 Sucrase-isomaltase deficiency, congenital; csid P14410
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#277700 Werner syndrome; wrn Q14191
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253


KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00783 Febrile seizures O14764 (related)
P18507 (related)
H00026 Endometrial Cancer P03372 (marker)
P04637 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
P68871 (marker)
H00022 Bladder cancer P04637 (related)
P68871 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04637 (related)
P38398 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
P38398 (related)
H00032 Thyroid cancer P04637 (related)
P27487 (marker)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
P37058 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H01205 Coumarin resistance P11712 (related)
H00115 Congenital sucrase-isomaltase deficiency P14410 (related)
H00808 Idiopathic generalized epilepsies (IGEs) P14867 (related)
P18507 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00208 Hyperbilirubinemia P22309 (related)
Q92887 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00192 Xanthinuria P47989 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
Q14191 (related)
H00228 Thalassemia P68871 (related)
H00229 Sickle cell anemia (SCA) P68871 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00236 Congenital polycythemia Q9GZT9 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

14 disease in interactions with metabolites

D005355 Fibrosis C00001022
D009369 Neoplasms C00001022
D000647 Amnesia C00001022
D005909 Glioblastoma C00001022
D006930 Hyperalgesia C00001022
D008175 Lung Neoplasms C00001022
D009361 Neoplasm Invasiveness C00001022
D056486 Drug-Induced Liver Injury C00001022
D002545 Brain Ischemia C00001024
D007249 Inflammation C00001024
D008106 Liver Cirrhosis, Experimental C00001024
D008107 Liver Diseases C00001024
D011471 Prostatic Neoplasms C00001024
D015427 Reperfusion Injury C00001024