Aspergillus fumigatus

• Index
• Plant Species
• Metabolite list (44)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Aspergillus fumigatus
Genus	Aspergillus
Family	Trichocomaceae
Kingdom	Fungi

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Aspergillus fumigatus
Linked NCBI taxonomy ID	746128
Linked level	species

Family

Family in NCBI taxonomy	Aspergillaceae
ID	1131492

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Fungi
ID	4751

Plant class

Plant class
ID

Metabolite list (44)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00023558	FTE / Tryptoquivaline E					No. 597
C00023559	Tryptoquivaline F	CHEMBL557488				No. 597
C00023561	Tryptoquivaline H					No. 597
C00023555	FTD / Tryptoquivaline D / Nortryptoquivaline / Norisotryptoquivaline					No. 597
C00023553	FTC / Tryptoquivaline / Tryptoquivaline A / Tryptoquivaline C'	CHEMBL1399348	C010522	6 / 8 / 4	1 / 0	No. 597
C00023562	Tryptoquivaline I					No. 597
C00023563	FTJ / Tryptoquivaline J	CHEMBL557488				No. 597
C00023564	Tryptoquivaline L					No. 597
C00023565	Tryptoquivaline M					No. 597
C00023566	Tryptoquivaline N / Deoxynortryptoquivalone					No. 597
C00023560	FTG / Tryptoquivaline G					No. 597
C00023904	Fumigacin / Helvolic acid	CHEMBL505132	C011267			No. 725
C00023758	Ergosta-4,6,8(14),22-tetraen-3-one	CHEMBL1801892 CHEMBL2040598	C015860			No. 768
C00011248	Fumigaclavine B					No. 803
C00011246	Fumigaclavine A					No. 803
C00026834	Fumiquinazoline E / (-)-Fumiquinazoline E					No. 964
C00028284	Fumiquinazoline A					No. 964
C00028286	Fumiquinazoline D	CHEMBL479913		1 / 0 / 0		No. 964
C00026833	Fumiquinazoline C / -)-Fumiquinazoline C	CHEMBL479913		1 / 0 / 0		No. 964
C00028285	Fumiquinazoline B					No. 964
C00001717	Elymoclavine	CHEMBL1356713	C007586	9 / 12 / 17	0 / 2	No. 987	No. 4
C00001707	Chanoclavine-I		C006959			No. 987	No. 4
C00011297	Fumitremorgin B		C039286			No. 1307
C00011301	TR-2 / TR 2 toxin / Verruculogen TR 2		C039287			No. 1307
C00021904	trans-beta-Bergamotene					No. 1653	No. 38
C00001392	L-Selenocystathionine					No. 2039
C00015154	Sch 528647					No. 2065
C00043519	Fumagiringillin					No. 2065
C00003133	Fumidil / Fugillin / Fumadil B / Amebacilin / Fumagillin / Fumagillin DCH / (-)-Fumagillin	CHEMBL32838 CHEMBL117603 CHEMBL1396346 CHEMBL1522710 CHEMBL1992691	C026211	13 / 20 / 23	3 / 3	No. 2065
C00011298	Fumitremorgin C	CHEMBL410316		4 / 4 / 1		No. 2184
C00016145	Tryprostatin A / (-)-Tryprostatin A / (3S-trans)-Hexahydro-3-[[6-methoxy-2-(3-methyl-2-butenyl)-1H-indol-3-yl]methyl]-pyrrolo[1,2-a]pyrazine-1,4-dione	CHEMBL38718 CHEMBL39220 CHEMBL39517 CHEMBL289159		3 / 3 / 0		No. 2184
C00016146	Tryprostatin B / (3S-trans)-Hexahydro-3-[[2-(3-methyl-2-butenyl)-1H-indol-3-yl]methyl]-pyrrolo[1,2-a]pyrazine-1,4-dione	CHEMBL36668 CHEMBL35821 CHEMBL288188 CHEMBL38396		1 / 0 / 0		No. 2184
C00034233	Se-Methylselenomethionine					No. 2513
C00035954	5-Demethoxyfumagillol					No. 3278
C00016255	Spirotriprostatin / Spirotryprostatin B / (-)-Spirotriprostatin / (-)-Spirotryprostatin B					No. 3882
C00026639	Spirotryprostatin A / (-)-Spirotryprostatin A	CHEMBL549475				No. 3882
C00011299	TR 1 toxin / Verruculogen / Verruculogen TR 1	CHEMBL463268	C009658			No. 3951
C00011296	Fumitremorgin A		C024743			No. 3951
C00011250	Fumigaclavine C					No. 3970
C00018709	Trypacidin					No. 4830
C00048859	Spirotryprostatin D / (-)-Spirotryprostatin D					No. 5441
C00048858	Spirotryprostatin C / (-)-Spirotryprostatin C					No. 5441
C00002340	Gliotoxin	CHEMBL331627 CHEMBL1972524	D005912	8 / 2 / 3	7 / 1	No. 5539
C00016193	Acetophthalidin					No. 7918

Human Protein / Gene in interactions

34 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P11473	Vitamin D3 receptor	NR1I1	C00001717 C00002340 C00003133	2 / 3
P11388	DNA topoisomerase 2-alpha	Isomerase	C00016145 C00016146	0 / 0
O00255	Menin	Unclassified protein	C00001717 C00003133	2 / 5
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002340 C00003133	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00001717 C00003133	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00001717 C00003133	1 / 2
P08183	Multidrug resistance protein 1	drug	C00011298 C00016145	1 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00001717 C00003133	4 / 3
O75496	Geminin	Unclassified protein	C00003133 C00023553	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00026833 C00028286	0 / 0
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00011298 C00016145	2 / 0
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00011298	1 / 1
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00001717	0 / 0
P53582	Methionine aminopeptidase 1	M24A	C00003133	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00001717	3 / 3
Q8WTS6	Histone-lysine N-methyltransferase SETD7	Enzyme	C00002340	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00023553	7 / 3
Q9Y253	DNA polymerase eta	Enzyme	C00023553	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00023553	0 / 0
Q9Y2T6	G-protein coupled receptor 55	Lysophosphatidylinositol receptor	C00023553	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001717	0 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00003133	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00003133	0 / 0
P50579	Methionine aminopeptidase 2	M24A	C00003133	0 / 0
P06732	Creatine kinase M-type	Enzyme	C00002340	0 / 0
O43463	Histone-lysine N-methyltransferase SUV39H1	Enzyme	C00002340	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00001717	0 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00011298	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00003133	11 / 10
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00003133	0 / 0
P49356	Protein farnesyltransferase subunit beta	Enzyme	C00002340	0 / 0
P49354	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	Enzyme	C00002340	0 / 0
P53609	Geranylgeranyl transferase type-1 subunit beta	Enzyme	C00002340	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00023553	0 / 0

11 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
9429	ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1	ATP-binding cassette, sub-family G (WHITE), member 2	C00023553
23173	METAP1, MAP1A, MetAP1A	methionyl aminopeptidase 1 (EC:3.4.11.18)	C00003133
10988	METAP2, MAP2, MNPEP, p67, p67eIF2	methionyl aminopeptidase 2 (EC:3.4.11.18)	C00003133
7532	YWHAG, 14-3-3GAMMA	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	C00003133
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00002340
3458	IFNG, IFG, IFI	interferon, gamma	C00002340
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00002340
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00002340
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00002340
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00002340
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002340

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions