Cyperus rotundus

• Index
• Plant Species
• Metabolite list (38)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Cyperus rotundus
Genus	Cyperus
Family	Cyperaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Cyperus rotundus
Linked NCBI taxonomy ID	512623
Linked level	species

Family

Family in NCBI taxonomy	Cyperaceae
ID	4609

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Liliopsida
ID	4447

Metabolite list (38)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00005515	Rhamnetin 3-rhamnosyl-(1->4)-rhamnoside					No. 1	No. 15
C00003186	beta-Selinene		C087920			No. 151	No. 38
C00012748	Isocyperol / (-)-Eudesma-4(14),11-dien-3alpha-ol / [2R-(2alpha,4abeta,7beta,8aalpha)]-Decahydro-4a-methyl-1-methylene-7-(1-methylethenyl)-2-naphthalenol	CHEMBL489542				No. 151	No. 38
C00034741	Valencene					No. 151	No. 38
C00016993	Nootkatene / (-)-Nootkatene					No. 151	No. 38
C00030189	epi-alpha-Selinene					No. 151	No. 38
C00029672	alpha-Selinene / (-)-alpha-Selinene					No. 151	No. 38
C00020130	gamma-Muurolene / 1beta-Cadina-4,10(15)-diene					No. 283	No. 39
C00029671	alpha-Muurolene					No. 283	No. 39
C00021865	Copadiene					No. 333	No. 38
C00003118	Copaene / alpha-Copaene / (-)-alpha-Copaene					No. 333	No. 38
C00008027	Aureusidin	CHEMBL593229				No. 450	No. 13
C00020112	Cadalin / Cadalene / 1,6-Dimethyl-4-isopropylnaphthalene					No. 647	No. 38
C00012740	Cyperol					No. 748
C00037928	trans-Calamenene					No. 824
C00021877	Rotundene					No. 926
C00012759	(+)-alpha-Cyperone / Eudesma-4,11-dien-3-one / (4aS-cis)-4,4a,5,6,7,8-Hexahydro-1,4a-dimethyl-7-(1-methylethenyl)-2(3H)-naphthalenone	CHEMBL1939885		1 / 1 / 1		No. 927
C00012841	alpha-Rotunol / [4aS-(4aalpha,6beta,8abeta)]-4a,5,6,7,8,8a-hexahydro-4a-hydroxy-4,8a-dimethyl-6-(1-methylethenyl)-2(1H)-naphthalenone					No. 1215
C00012842	beta-Rotunol / (+)-beta-Rotunol / [4aR-(4aalpha,6alpha,8aalpha)]-4a,5,6,7,8,8a-hexahydro-4a-hydroxy-4,8a-dimethyl-6-(1-methylethenyl)-2(1H)-naphthalenone					No. 1215
C00021870	Mustakone	CHEMBL498895				No. 1243
C00036991	Cypera-2,4-diene / (-)-Cypera-2,4-diene					No. 1454
C00021283	Cyperene					No. 1454
C00036992	Cyprotene					No. 1454
C00007636	delta-Cadinene	CHEMBL445759				No. 1524	No. 39
C00012492	Kobusone / (-)-Kobusone	CHEMBL1592474		1 / 0 / 1		No. 1620
C00020397	Rotundone					No. 1674	No. 38
C00020070	gamma-Calacorene					No. 1859
C00021284	Cyperotundone / Isopatchoulenone					No. 1999	No. 38
C00012491	Isokobusone	CHEMBL1522104		1 / 0 / 1		No. 3188
C00021910	Cyperolone					No. 3645
C00020383	gamma-Gurjunene / (+)-gamma-Gurjunene	CHEMBL455046				No. 3712	No. 38
C00020378	Epoxyguaiene / 1alpha,5alpha-Epoxy-alpha-guaiene					No. 4184
C00012741	4alpha,5alpha-Epoxy-11-eudesmen-3alpha-ol / [1aR-(1aalpha,2alpha,4aalpha,7alpha,8aS*)]-Octahydro-1a,4a-dimethyl-7-(1-methylethenyl)-3H-naphth[1,8a-b]oxiren-2-ol					No. 4184
C00047086	Rotundine A / (-)-Rotundine A					No. 4333
C00047087	Rotundine B / (-)-Rotundine B					No. 4333
C00047088	Rotundine C / (-)-Rotundine C					No. 4333
C00001425	Octopamine	CHEMBL53929 CHEMBL1160703	D009655	16 / 8 / 6	7 / 0	No. 4586
C00002985	Cyperine	CHEMBL487020				No. 4808

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001425 C00012491 C00012492	0 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001425	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00001425	2 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00001425	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00001425	3 / 2
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00001425	0 / 1
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00001425	0 / 0
P46098	5-hydroxytryptamine receptor 3A	NS	C00001425	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00001425	1 / 1
P03372	Estrogen receptor	NR3A1	C00012759	1 / 1
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00001425	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001425	1 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001425	1 / 0
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00001425	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00001425	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00001425	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001425	0 / 0

7 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
153	ADRB1, ADRB1R, B1AR, BETA1AR, RHR	adrenoceptor beta 1	C00001425
154	ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR	adrenoceptor beta 2, surface	C00001425
155	ADRB3, BETA3AR	adrenoceptor beta 3	C00001425
6530	SLC6A2, NAT1, NET, NET1, SLC6A5	solute carrier family 6 (neurotransmitter transporter), member 2	C00001425
6531	SLC6A3, DAT, DAT1, PKDYS	solute carrier family 6 (neurotransmitter transporter), member 3	C00001425
6532	SLC6A4, 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT	solute carrier family 6 (neurotransmitter transporter), member 4	C00001425
134864	TAAR1, RP11-295F4.9, TA1, TAR1, TRAR1	trace amine associated receptor 1	C00001425

Related Diseases

Diseases related to proteins in ChEMBL interactions