Species

KNApSAcK Entry

Organism name Cryptocarya chinensis
Genus Cryptocarya
Family Lauraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Cryptocarya chinensis
Linked NCBI taxonomy ID 128609
Linked level species

Family

Family in NCBI taxonomy Lauraceae
ID 3433

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (29)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001861 External link 512 Glaucine
/ S-(+)-Glaucine
/ O,O-Dimethylisoboldine
CHEMBL36536
CHEMBL228082
14 / 8 / 6 No. 20 No. 4
C00045864 External link 512 dl-Caryachine
CHEMBL480663
1 / 1 / 0 No. 37 No. 4
C00001809 External link 512 (-)-Argemonine
CHEMBL486987
CHEMBL1964569
No. 37 No. 4
C00025402 External link 512 Norargemonine
/ (-)-Norargemonine
/ O2-Demetylargemonie
/ O8-Demethylargemonine
CHEMBL1570385
2 / 2 / 0 No. 37 No. 4
C00027171 External link 512 (-)-Isocaryachine
No. 37 No. 4
C00001855 External link 512 Eschscholtzidine
/ O-Methylcaryachine
CHEMBL1621815
No. 37 No. 4
C00045475 External link 512 (+)-Eschscholtzidine
CHEMBL1621815
No. 37 No. 4
C00027174 External link 512 (+)-Isocaryachine
No. 37 No. 4
C00045473 External link 512 (+)-Caryachine
CHEMBL480663
1 / 1 / 0 No. 37 No. 4
C00027224 External link 512 Neocaryachine
No. 37 No. 4
C00049038 External link 512 (+)-O-Methylcaryachine
CHEMBL1621815
No. 37 No. 4
C00027420 External link 512 N-Demethylcrychine
/ (-)-N-Demethylcrychine
CHEMBL349696
No. 233 No. 4
C00027249 External link 512 12-Hydroxycrychine
/ (-)-12-Hydroxycrychine
No. 233 No. 4
C00027202 External link 512 Cinnamolaurine
No. 253 No. 4
C00027226 External link 512 Norarmepavine
/ (-)-Norarmepavine
CHEMBL510363
CHEMBL453038
9 / 14 / 7 No. 253 No. 4
C00027382 External link 512 Isoboldine beta-N-oxide
No. 286 No. 4
C00046196 External link 512 N-Demethylphyllocryptine
No. 345 No. 4
C00027383 External link 512 Isocaryachine N-oxide
/ (+)-Isocaryachine-N-oxide
No. 526
C00027172 External link 512 (-)-Isocaryachine N-oxide
No. 526
C00045476 External link 512 (+)-Eschscholtzidine N-oxide
No. 526
C00027173 External link 512 (-)-N-methylcaryachine
No. 526
C00045472 External link 512 (+)-8,9-Dihydrostepharine
No. 1032
C00027176 External link 512 1-Hydroxycryprochine
No. 1032
C00028105 External link 512 Cryprochine
No. 1032
C00027388 External link 512 Isocryprochine
No. 1032
C00027262 External link 512 8,9-Dihydrostepharine
No. 1032
C00027381 External link 512 Isoamuronine
No. 1032
C00045866 External link 512 Doryanine
No. 5730
C00046329 External link 512 Prooxocryptochine
No. 7671

Human Protein / Gene in interactions

23 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O75496 Geminin Unclassified protein C00001861 C00025402 C00027226 0 / 0
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor C00045473 C00045864 1 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00025402 C00027226 2 / 0
Q99700 Ataxin-2 Unclassified protein C00027226 1 / 1
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00001861 1 / 0
Q9BQF6 Sentrin-specific protease 7 Enzyme C00001861 0 / 0
Q9GZR1 Sentrin-specific protease 6 Enzyme C00001861 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00027226 2 / 3
Q14761 Protein tyrosine phosphatase receptor type C-associated protein Enzyme C00001861 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00001861 0 / 0
Q96LD8 Sentrin-specific protease 8 Enzyme C00001861 0 / 0
P42574 Caspase-3 C14 C00001861 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00027226 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00027226 7 / 3
P83916 Chromobox protein homolog 1 Unclassified protein C00027226 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00001861 3 / 3
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001861 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00001861 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00001861 4 / 3
P49798 Regulator of G-protein signaling 4 Unclassified protein C00027226 2 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001861 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00027226 0 / 0
P43351 DNA repair protein RAD52 homolog Unclassified protein C00001861 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (23)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#114500 Colorectal cancer; crc P84022
#600274 Frontotemporal dementia; ftd P10636
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#166350 Osseous heteroplasia, progressive; poh P63092
#260540 Parkinson-dementia syndrome P10636
#614674 Periodic fever, menstrual cycle-dependent P08908
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (13)

KEGG name UniProt
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)