| Organism name | Phoebe minutiflora |
|---|---|
| Genus | Phoebe |
| Family | Lauraceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Phoebe minutiflora |
|---|---|
| Linked NCBI taxonomy ID | 1053126 |
| Linked level | species |
| Family in NCBI taxonomy | Lauraceae |
|---|---|
| ID | 3433 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | Magnoliophyta |
|---|---|
| ID | 3398 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00027433
|
Laurolitsine
/ (+)-Norboldine / (+)-Laurolitsine |
CHEMBL487388
|
C109133
|
No. 20 | No. 4 |
|
||
|
C00001869
|
Isoboldine
/ (S)-Isoboldine |
CHEMBL462880
|
19 / 22 / 55 | No. 20 | No. 4 |
|
||
|
C00025655
|
Corytuberine
/ (+)-Corytuberine |
CHEMBL227965
|
C013896
|
1 / 0 / 0 | No. 20 | No. 4 |
|
|
|
C00027438
|
Sanjoinine Ib
/ Norisocorydine |
CHEMBL465212
|
No. 20 | No. 4 |
|
|||
|
C00027440
|
Norjuziphine
/ (-)-Norjusiphine / (-)-Norjuziphine |
CHEMBL462757
|
No. 253 | No. 4 |
|
|||
|
C00025812
|
Coclaurine
/ (S)-Coclaurine / (-)-Coclaurine |
CHEMBL256448
CHEMBL453291 CHEMBL446211 |
C004690
|
8 / 17 / 10 | No. 253 | No. 4 |
|
|
|
C00025924
|
Juziphine
/ Yuziphine / (+)-Juziphine |
CHEMBL462956
|
No. 253 | No. 4 |
|
|||
|
C00001810
|
Armepavine
/ (-)-Armepavine / (R)-(-)-Armepavine |
CHEMBL451722
CHEMBL1186477 CHEMBL1186510 |
7 / 5 / 3 | No. 345 | No. 4 |
|
||
|
C00001910
|
Reticuline
/ (+)-Reticuline |
CHEMBL235212
CHEMBL401501 CHEMBL464734 |
C003298
|
1 / 0 / 0 | No. 345 | No. 4 |
|
|
|
C00001875
|
Tritopin
/ Tritopine / Laudanidine / (-)-Laudanidine |
CHEMBL251625
CHEMBL1425007 |
2 / 0 / 0 | No. 345 | No. 4 |
|
||
|
C00027430
|
N-Methylsecoglaucine
|
CHEMBL1620038
|
No. 639 |
|
||||
|
C00027424
|
N-Methylarmepavine
|
CHEMBL1187350
|
No. 896 |
|
||||
|
C00027451
|
O-Methylcorypalline
|
CHEMBL1196025
|
No. 1686 | No. 4 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001810 C00001875 C00025812 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001810 C00001869 C00025812 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001869 C00025812 | 4 / 3 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001810 C00025812 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001810 C00001869 | 3 / 3 |
| O75496 | Geminin | Unclassified protein | C00001875 C00025812 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001810 C00001869 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001810 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00001810 | 2 / 0 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00025655 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00025812 | 7 / 3 |
| P29466 | Caspase-1 | C14 | C00001869 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00001869 | 2 / 2 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00001910 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001869 | 0 / 1 |
| P55210 | Caspase-7 | C14 | C00001869 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001869 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001869 | 0 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001869 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00025812 | 6 / 4 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001869 | 0 / 0 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00025812 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00001869 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00001869 | 7 / 37 |
| O00255 | Menin | Unclassified protein | C00001869 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001869 | 1 / 2 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001869 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001869 | 1 / 4 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001869 | 1 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #133239 | Esophageal cancer |
P04637
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #211980 | Lung cancer |
P04637
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00026 | Endometrial Cancer |
P04637
(related)
|
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|