Pachygone ovata Miers
Species
KNApSAcK Entry
| Organism name | Pachygone ovata Miers |
|---|---|
| Genus | Pachygone |
| Family | Menispermaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Pachygone |
|---|---|
| Linked NCBI taxonomy ID | 152360 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Menispermaceae |
|---|---|
| ID | 3455 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Metabolite list (13)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00026066
|
Tiliamosine
|
No. 10 | No. 4 |
|
||||
|
C00025999
|
Pachygonamine
|
No. 10 | No. 4 |
|
||||
|
C00026001
|
Pachyovatamine
|
No. 10 | No. 4 |
|
||||
|
C00025958
|
N-Methylpachygonamine
|
No. 10 | No. 4 |
|
||||
|
C00025965
|
Nortrilobine
/ N2'-Demethyltrilobine |
No. 10 | No. 4 |
|
||||
|
C00025962
|
Norisoboldine
/ Laurelliptine / (+)-Norisoboldine / (+)-Laurelliptine / (+)-N-Norisoboldine / (S)-(+)-Laurelliptine |
CHEMBL375902
|
No. 20 | No. 4 |
|
|||
|
C00026094
|
Stepholidine
/ (-)-Stepholidine |
CHEMBL487387
CHEMBL2334890 |
C010513
|
7 / 4 / 0 | 0 / 1 | No. 37 | No. 4 |
|
|
C00025233
|
Coramine
/ Coreximin / Coreximine / (S)-Coreximine / (-)-Coreximine / Coramine(alkaloid) |
CHEMBL1164087
|
No. 37 | No. 4 |
|
|||
|
C00025812
|
Coclaurine
/ (S)-Coclaurine / (-)-Coclaurine |
CHEMBL256448
CHEMBL453291 CHEMBL446211 |
C004690
|
8 / 17 / 10 | No. 253 | No. 4 |
|
|
|
C00025977
|
O,O'-Dimethylmagnoflorine
|
No. 286 | No. 4 |
|
||||
|
C00001862
|
Glaziovine
/ L-Glaziovine / N-Methylcrotsparine / L-(-)-N-Methylcrotsparine |
CHEMBL1980854
|
C007847
|
No. 688 |
|
|||
|
C00026024
|
Reticuline N-oxide
|
CHEMBL1402907
|
7 / 7 / 4 | No. 896 |
|
|||
|
C00026000
|
Pachygonine
|
No. 6284 |
|
Human Protein / Gene in interactions
19 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00025812 C00026024 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00025812 C00026024 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00025812 C00026024 | 4 / 3 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00026094 | 0 / 0 |
| P21918 | D(1B) dopamine receptor | Dopamine receptor | C00026094 | 1 / 0 |
| Q9HBX9 | Relaxin receptor 1 | Relaxin receptor | C00026024 | 0 / 0 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00026094 | 2 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00026024 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00025812 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00026024 | 1 / 1 |
| Q9Y256 | CAAX prenyl protease 2 | U48 | C00026024 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00025812 | 7 / 3 |
| P13726 | Tissue factor | Membrane receptor | C00026094 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00026094 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00025812 | 6 / 4 |
| P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00026094 | 1 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00026094 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00025812 | 0 / 0 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00025812 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (24)
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #103780 | Alcohol dependence |
P14416
|
| #606798 | Blepharospasm, benign essential |
P21918
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #159900 | Myoclonic dystonia |
P14416
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
KEGG DISEASE (11)
| KEGG | name | UniProt |
|---|---|---|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|