Species

KNApSAcK Entry

Organism name Glycosmis arborea
Genus Glycosmis
Family Rutaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Glycosmis
Linked NCBI taxonomy ID 68543
Linked level genus

Family

Family in NCBI taxonomy Rutaceae
ID 23513

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (21)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00046778 External link 512 Isoarborinol
No. 198 No. 52
C00026905 External link 512 Glycozolidine
CHEMBL463555
No. 239
C00026904 External link 512 Glycozoline
C034053
No. 239
C00026591 External link 512 Glybomine A
No. 239
C00002137 External link 512 Arborinine
CHEMBL349609
C022784
1 / 0 / 0 No. 257 No. 7
C00024708 External link 512 Glycomaurrol
No. 437
C00026592 External link 512 Glybomine B
CHEMBL459130
No. 437
C00026593 External link 512 Glybomine C
CHEMBL459131
No. 437
C00044783 External link 512 Glycoborinine
CHEMBL506671
No. 516
C00026444 External link 512 Iso-gamma-fagarine
CHEMBL447997
6 / 2 / 2 No. 624 No. 7
C00002174 External link 512 Isodictamine
/ Isodictamnine
CHEMBL509839
No. 624 No. 7
C00044784 External link 512 Glycozolinine
No. 751
C00038258 External link 512 3-Methylcarbazole
CHEMBL1173768
C110004
1 / 1 / 0 No. 751
C00026387 External link 512 O-Methylglycosolone
/ 4,8-Dimethoxy-1-methyl-3-prenylquinolin-2-one
No. 781
C00039755 External link 512 Methyl carbazole-3-carboxylate
CHEMBL446253
1 / 1 / 0 No. 807
C00026402 External link 512 Acutifolin
No. 1903 No. 7
C00002168 External link 512 Glycosminine
CHEMBL1604716
C015247
4 / 1 / 2 No. 2751 No. 7
C00002136 External link 512 Arborine
CHEMBL448122
C014013
No. 2751 No. 7
C00026245 External link 512 Glycosminine
/ Glycophymine
/ N-Demethylarborine
CHEMBL1604716
C015247
4 / 1 / 2 No. 2751 No. 7
C00026432 External link 512 Glycocitlone C
No. 3133
C00044432 External link 512 2-Quinolone
CHEMBL186422
C107724
19 / 7 / 9 1 / 0 No. 3673

Human Protein / Gene in interactions

31 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002168 C00026245 0 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00002168 C00026245 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00002168 C00026245 0 / 0
P52732 Kinesin-like protein KIF11 Other cytosolic protein C00038258 C00039755 1 / 0
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00002168 C00026245 1 / 2
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00026444 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00044432 2 / 2
Q8N1Q1 Carbonic anhydrase 13 Lyase C00044432 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00044432 1 / 2
P23280 Carbonic anhydrase 6 Lyase C00044432 0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00044432 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00026444 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00044432 1 / 2
O75496 Geminin Unclassified protein C00026444 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00044432 0 / 0
P22894 Neutrophil collagenase M10A C00044432 0 / 0
P03956 Interstitial collagenase M10A C00044432 0 / 1
P43166 Carbonic anhydrase 7 Lyase C00044432 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00026444 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00044432 0 / 1
P08253 72 kDa type IV collagenase M10A C00044432 1 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00026444 2 / 2
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00044432 0 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00044432 0 / 0
P07451 Carbonic anhydrase 3 Lyase C00044432 0 / 0
P08254 Stromelysin-1 M10A C00044432 1 / 0
P22748 Carbonic anhydrase 4 Lyase C00044432 1 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00044432 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00026444 0 / 0
P33765 Adenosine receptor A3 Adenosine receptor C00002137 0 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00044432 0 / 0

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
5444 PON1, ESA, MVCD5, PON paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) C00044432

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM preferred title UniProt
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#119900 Digital clubbing, isolated congenital P15428
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#143860 Hyperchlorhidrosis, isolated O43570
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#603932 Intervertebral disc disease; idd P14780
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#152950 Microcephaly with or without chorioretinopathy, lymphedema, or mental retardation; mclmr P52732
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#600852 Retinitis pigmentosa 17; rp17 P22748

KEGG DISEASE (13)

KEGG name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00028 Choriocarcinoma P03956 (related)
P08253 (related)
H00025 Penile cancer P08253 (related)
P14780 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)