KEGG   COMPOUND: C00022
Entry
C00022                      Compound                               
Name
Pyruvate;
Pyruvic acid;
2-Oxopropanoate;
2-Oxopropanoic acid;
Pyroracemic acid
Formula
C3H4O3
Exact mass
88.016
Mol weight
88.0621
Structure
Reaction
R00006 R00008 R00014 R00195 R00196 R00197 R00198 R00199
R00200 R00203 R00205 R00206 R00207 R00208 R00209 R00210
R00211 R00212 R00213 R00214 R00215 R00216 R00217 R00218
R00219 R00220 R00221 R00223 R00224 R00226 R00237 R00258
R00297 R00324 R00325 R00344 R00350 R00353 R00368 R00369
R00396 R00398 R00400 R00409 R00430 R00452 R00453 R00470
R00471 R00532 R00543 R00562 R00572 R00576 R00585 R00659
R00666 R00673 R00692 R00703 R00704 R00724 R00728 R00750
R00782 R00906 R00907 R00930 R00985 R00986 R01012 R01031
R01032 R01064 R01085 R01138 R01147 R01148 R01196 R01215
R01261 R01286 R01302 R01335 R01344 R01355 R01447 R01576
R01584 R01645 R01647 R01683 R01699 R01712 R01782 R01784
R01811 R01858 R01874 R02050 R02261 R02271 R02293 R02320
R02408 R02628 R02721 R02754 R02953 R02970 R03001 R03037
R03050 R03081 R03105 R03145 R03277 R03465 R03502 R03528
R03732 R03796 R03854 R04152 R04187 R04350 R04672 R04861
R04941 R05136 R05298 R05538 R05544 R05553 R05605 R05636
R05648 R05652 R05861 R06602 R06603 R06913 R06923 R06934
R07399 R07633 R07634 R07685 R07692 R07713 R08166 R08170
R08197 R08200 R08253 R08570 R08648 R08654 R08660 R08667
R08686 R08698 R08714 R09048 R09088 R09238 R09254 R09366
R10147 R10178 R10180 R10283 R10487 R10527 R10539 R10542
R10550 R10552 R10583 R10597 R10616 R10674 R10691 R10866
R10992 R11023 R11038 R11099 R11141 R11213 R11257 R11352
R11463 R11591 R11593 R11676 R11864 R11996 R12188 R12212
R12237 R12343 R12622 R12689 R12707 R12768 R13049 R13050
R13181
 » show all
Pathway
map00010  Glycolysis / Gluconeogenesis
map00020  Citrate cycle (TCA cycle)
map00030  Pentose phosphate pathway
map00040  Pentose and glucuronate interconversions
map00053  Ascorbate and aldarate metabolism
map00250  Alanine, aspartate and glutamate metabolism
map00260  Glycine, serine and threonine metabolism
map00261  Monobactam biosynthesis
map00270  Cysteine and methionine metabolism
map00290  Valine, leucine and isoleucine biosynthesis
map00330  Arginine and proline metabolism
map00350  Tyrosine metabolism
map00360  Phenylalanine metabolism
map00362  Benzoate degradation
map00430  Taurine and hypotaurine metabolism
map00440  Phosphonate and phosphinate metabolism
map00470  D-Amino acid metabolism
map00620  Pyruvate metabolism
map00621  Dioxin degradation
map00622  Xylene degradation
map00630  Glyoxylate and dicarboxylate metabolism
map00650  Butanoate metabolism
map00660  C5-Branched dibasic acid metabolism
map00680  Methane metabolism
map00710  Carbon fixation in photosynthetic organisms
map00720  Carbon fixation pathways in prokaryotes
map00730  Thiamine metabolism
map00760  Nicotinate and nicotinamide metabolism
map00770  Pantothenate and CoA biosynthesis
map00785  Lipoic acid metabolism
map00900  Terpenoid backbone biosynthesis
map00997  Biosynthesis of various other secondary metabolites
map00998  Biosynthesis of various antibiotics
map01060  Biosynthesis of plant secondary metabolites
map01061  Biosynthesis of phenylpropanoids
map01062  Biosynthesis of terpenoids and steroids
map01063  Biosynthesis of alkaloids derived from shikimate pathway
map01064  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
map01065  Biosynthesis of alkaloids derived from histidine and purine
map01066  Biosynthesis of alkaloids derived from terpenoid and polyketide
map01070  Biosynthesis of plant hormones
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
map01210  2-Oxocarboxylic acid metabolism
map01220  Degradation of aromatic compounds
map01230  Biosynthesis of amino acids
map01240  Biosynthesis of cofactors
map01502  Vancomycin resistance
map02060  Phosphotransferase system (PTS)
map04066  HIF-1 signaling pathway
map04152  AMPK signaling pathway
map04911  Insulin secretion
map04922  Glucagon signaling pathway
map04930  Type II diabetes mellitus
map04931  Insulin resistance
map05230  Central carbon metabolism in cancer
map05415  Diabetic cardiomyopathy
Module
M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
M00002  Glycolysis, core module involving three-carbon compounds
M00008  Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate
M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
M00061  D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P
M00096  C5 isoprenoid biosynthesis, non-mevalonate pathway
M00169  CAM (Crassulacean acid metabolism), light
M00171  C4-dicarboxylic acid cycle, NAD - malic enzyme type
M00172  C4-dicarboxylic acid cycle, NADP - malic enzyme type
M00173  Reductive citrate cycle (Arnon-Buchanan cycle)
M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
M00308  Semi-phosphorylative Entner-Doudoroff pathway, gluconate => glycerate-3P
M00309  Non-phosphorylative Entner-Doudoroff pathway, gluconate/galactonate => glycerate
M00374  Dicarboxylate-hydroxybutyrate cycle
M00376  3-Hydroxypropionate bi-cycle
M00535  Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
M00620  Incomplete reductive citrate cycle, acetyl-CoA => oxoglutarate
M00631  D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P
M00633  Semi-phosphorylative Entner-Doudoroff pathway, gluconate/galactonate => glycerate-3P
M00975  Betaine degradation, bacteria, betaine => pyruvate
Network
nt06031  Citrate cycle and pyruvate metabolism
nt06032  Lipoic acid metabolism
nt06166  Human papillomavirus (HPV)
Enzyme
1.1.1.27        1.1.1.28        1.1.1.38        1.1.1.39        
1.1.1.40        1.1.1.83        1.1.1.436       1.1.2.3         
1.1.2.4         1.1.2.5         1.1.3.2         1.1.5.12        
1.1.99.6        1.1.99.7        1.1.99.40       1.2.1.22        
1.2.1.23        1.2.1.49        1.2.1.51        1.2.1.104       
1.2.3.3         1.2.3.6         1.2.3.15        1.2.4.1         
1.2.5.1         1.2.7.1         1.2.7.11        1.2.7.-         
1.4.1.1         1.4.1.17        1.4.3.3         1.4.3.19        
1.5.1.11        1.5.1.16        1.5.1.17        1.5.1.22        
1.5.1.23        1.5.1.24        1.5.1.26        1.5.1.28        
1.5.1.52        1.14.11.43      1.14.11.44      2.1.3.1         
2.2.1.6         2.2.1.7         2.2.1.12        2.3.1.54        
2.3.3.21        2.6.1.2         2.6.1.12        2.6.1.15        
2.6.1.18        2.6.1.21        2.6.1.30        2.6.1.37        
2.6.1.40        2.6.1.41        2.6.1.43        2.6.1.44        
2.6.1.46        2.6.1.47        2.6.1.51        2.6.1.56        
2.6.1.58        2.6.1.66        2.6.1.71        2.6.1.77        
2.6.1.84        2.6.1.96        2.6.1.99        2.6.1.108       
2.6.1.113       2.6.1.115       2.6.1.119       2.6.3.1         
2.7.1.40        2.7.1.121       2.7.3.9         2.7.9.1         
2.7.9.2         2.8.1.2         3.1.3.60        3.3.2.1         
3.3.2.13        3.3.2.15        3.5.99.10       3.7.1.5         
3.7.1.6         3.7.1.20        3.7.1.23        3.7.1.26        
3.7.1.-         3.11.1.3        4.1.1.1         4.1.1.64        
4.1.1.78        4.1.1.112       4.1.1.-         4.1.2.14        
4.1.2.18        4.1.2.20        4.1.2.21        4.1.2.23        
4.1.2.28        4.1.2.34        4.1.2.45        4.1.2.51        
4.1.2.52        4.1.2.53        4.1.2.54        4.1.2.55        
4.1.2.58        4.1.2.64        4.1.2.-         4.1.3.3         
4.1.3.16        4.1.3.17        4.1.3.22        4.1.3.25        
4.1.3.27        4.1.3.30        4.1.3.32        4.1.3.38        
4.1.3.39        4.1.3.40        4.1.3.42        4.1.3.43        
4.1.3.44        4.1.3.45        4.1.3.46        4.1.99.1        
4.1.99.2        4.2.1.-         4.2.99.20       4.2.99.21       
4.3.1.10        4.3.1.13        4.3.1.15        4.3.1.17        
4.3.1.18        4.3.1.19        4.3.3.7         4.3.3.8         
4.4.1.1         4.4.1.13        4.4.1.15        4.4.1.24        
4.4.1.25        4.4.1.28        4.4.1.35        4.4.1.36        
4.4.1.-         4.5.1.2         6.4.1.1         7.2.4.2
 » show all
Brite
Compounds with biological roles [BR:br08001]
 Organic acids
  Carboxylic acids
   2-Oxocarboxylic acids
    C00022  Pyruvate; 2-Oxopropanoate
Lipids [BR:br08002]
 FA  Fatty acyls
  FA01 Fatty Acids and Conjugates
   FA0106 Oxo fatty acids
    C00022  2-Oxopropanoic acid
Other DBs
CAS: 127-17-3
PubChem: 3324
ChEBI: 15361 32816
LIPIDMAPS: LMFA01060077
KNApSAcK: C00001200
PDB-CCD: PYR[PDBj]
3DMET: B00006
NIKKAJI: J2.015J
KCF data

ATOM        6
            1   C1a C    12.6924  -17.4300
            2   C5a C    13.9049  -16.7300
            3   C6a C    15.1173  -17.4300
            4   O6a O    16.3318  -16.7288
            5   O5a O    13.9049  -15.3302
            6   O6a O    15.1173  -18.8300
BOND        5
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     2   5 2
            5     3   6 2

» Japanese version

  All links  
Pathway (79)   
   KEGG PATHWAY (59)   
   KEGG MODULE (20)   
Network (7)   
   KEGG NETWORK (7)   
Chemical substance (17)   
   PubChem (1)   
   ChEBI (2)   
   3DMET (1)   
   HMDB (1)   
   KNApSAcK (1)   
   LIPIDBANK (1)   
   LIPIDMAPS (1)   
   MASSBANK (7)   
   NIKKAJI (1)   
   PDB-CCD (1)   
Chemical reaction (359)   
   KEGG ENZYME (150)   
   KEGG REACTION (209)   
Gene (323329)   
   KEGG GENES (323329)   
All databases (323791)   

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